2018
Patient Presentations in Outpatient Settings
Zogg CK, Haring RS, Xu L, Canner JK, Ottesen TD, Salim A, Haider AH, Schneider EB. Patient Presentations in Outpatient Settings. Epidemiology 2018, 29: 885-894. PMID: 30063541, PMCID: PMC6167152, DOI: 10.1097/ede.0000000000000900.Peer-Reviewed Original ResearchConceptsInjury-specific factorsOutpatient settingHead traumaTrauma patientsEmergency departmentIndex outpatient visitAmbulatory care useHead trauma patientsEmergency department careOutpatient presentationClinic visitsIndex presentationOutpatient visitsOutpatient burdenCare useOutpatient casesIncidence ratePatient presentationCommercial ClaimsTrauma diagnosisSubsequent visitsAnnual burdenTrauma trendsDisease controlPatientsAssociation Between Age and Patient‐Reported Changes in Voice and Swallowing After Thyroidectomy
Sahli Z, Canner J, Najjar O, Schneider E, Prescott J, Russell J, Tufano R, Zeiger M, Mathur A. Association Between Age and Patient‐Reported Changes in Voice and Swallowing After Thyroidectomy. The Laryngoscope 2018, 129: 519-524. PMID: 30194684, PMCID: PMC6344315, DOI: 10.1002/lary.27297.Peer-Reviewed Original ResearchConceptsSwallowing changesSwallowing alterationsRisk factorsIntraoperative recurrent laryngeal nerve monitoringIntact recurrent laryngeal nerveRecurrent laryngeal nerve monitoringPatient-reported voiceGastroesophageal reflux diseaseAdditional prospective studiesLaryngeal nerve monitoringRecurrent laryngeal nervePresence of malignancyImpact of ageInstitutional review boardIntact RLNReflux diseaseRLN injuryTotal thyroidectomyFrailty statusPatient ageConsecutive patientsFrailty indexRetrospective reviewLaryngeal nerveNerve monitoringConscious status is associated with the likelihood of trauma centre care and mortality in patients with moderate-to-severe traumatic brain injury
AlSulaim H, Haring R, Asemota A, Smart B, Canner J, Ejaz A, Efron D, Velopulos C, Haut E, Schneider E. Conscious status is associated with the likelihood of trauma centre care and mortality in patients with moderate-to-severe traumatic brain injury. Brain Injury 2018, 32: 784-793. PMID: 29561720, DOI: 10.1080/02699052.2018.1451658.Peer-Reviewed Original ResearchConceptsLoss of consciousnessNon-trauma centersTraumatic brain injuryTrauma centerBrain injuryHead/neck Abbreviated Injury Scale scoreNeck Abbreviated Injury Scale scoreLevel I/II trauma centersAbbreviated Injury Scale scoreSevere traumatic brain injuryInjury Scale scoreOdds of mortalityTrauma center careTC treatmentLogistic regression modelsHospital mortalityOlder patientsPatient demographicsPrimary outcomeInjury characteristicsNinth RevisionAIS scoreTBI outcomesPrevention criteriaClinical Modification
2016
Epidemiologic Trends of Chemical Ocular Burns in the United States
Haring R, Sheffield I, Channa R, Canner J, Schneider E. Epidemiologic Trends of Chemical Ocular Burns in the United States. JAMA Ophthalmology 2016, 134: 1119-1124. PMID: 27490908, DOI: 10.1001/jamaophthalmol.2016.2645.Peer-Reviewed Original ResearchConceptsChemical ocular burnsEmergency departmentOcular burnsEpidemiologic trendsAcid injuryHealth care insuranceChemical burnsNationwide Emergency Department SampleChemical eye injuriesEmergency department chargesTotal emergency departmentOcular chemical burnsOcular chemical injuryEmergency Department SampleHigh-risk groupSingle high-risk groupAge-specific ratesPrivate health care insuranceCare insuranceAlkali injuryED presentationsEye injuriesMedian agePatient ageFemale patientsThirty-day re-admission after traumatic brain injury: Results from MarketScan®
Canner J, Giuliano K, Gani F, Schneider E. Thirty-day re-admission after traumatic brain injury: Results from MarketScan®. Brain Injury 2016, 30: 1570-1575. PMID: 27589200, DOI: 10.1080/02699052.2016.1199898.Peer-Reviewed Original ResearchConceptsTraumatic brain injuryPrimary diagnosisBrain injuryHead Abbreviated Injury ScoreCharacteristics of patientsCommon primary diagnosisAbbreviated Injury ScoreRe-admission ratesInpatient rehabilitation facilityIndex dischargeMore comorbiditiesConcurrent injuriesIndex hospitalizationInjury scoreDischarge planningThirty-dayRehabilitation facilityPsychiatric disordersGreater oddsPatientsElucidate causesAge 65InjuryDiagnosisMarketScanFrailty predicts risk of life-threatening complications and mortality after pancreatic resections
Augustin T, Burstein M, Schneider E, Morris-Stiff G, Wey J, Chalikonda S, Walsh R. Frailty predicts risk of life-threatening complications and mortality after pancreatic resections. Surgery 2016, 160: 987-996. PMID: 27545992, DOI: 10.1016/j.surg.2016.07.010.Peer-Reviewed Original ResearchMeSH KeywordsAge FactorsAgedCause of DeathComorbidityDatabases, FactualFemaleFrail ElderlyHumansLogistic ModelsMaleMiddle AgedMultivariate AnalysisPancreatectomyPancreatic NeoplasmsPancreaticoduodenectomyPostoperative ComplicationsPredictive Value of TestsRetrospective StudiesRisk AssessmentROC CurveSeverity of Illness IndexSex FactorsSurvival AnalysisTreatment OutcomeConceptsNational Surgical Quality Improvement ProjectSurgical Quality Improvement ProjectGrade 4 complicationsFrailty indexQuality improvement projectGreater body mass indexDistal pancreatectomy patientsModified Frailty IndexOutcomes of pancreatoduodenectomyLow serum albuminLife-threatening complicationsPre-operative optimizationEffect of frailtySelection of patientsBody mass indexDegree of frailtyGreater weight lossImprovement projectIntermediate frailtyNonfrail patientsConsideration of frailtyDistal pancreatectomyFrail patientsOperative riskPancreatectomy patientsPredictors of emergency ventral hernia repair: Targets to improve patient access and guide patient selection for elective repair
Wolf LL, Scott JW, Zogg CK, Havens JM, Schneider EB, Smink DS, Salim A, Haider AH. Predictors of emergency ventral hernia repair: Targets to improve patient access and guide patient selection for elective repair. Surgery 2016, 160: 1379-1391. PMID: 27542434, DOI: 10.1016/j.surg.2016.06.027.Peer-Reviewed Original ResearchMeSH KeywordsAdultAge FactorsAgedAged, 80 and overConfidence IntervalsDatabases, FactualElective Surgical ProceduresEmergenciesFemaleFollow-Up StudiesHealth Services AccessibilityHernia, VentralHerniorrhaphyHospital MortalityHumansInsurance CoverageLogistic ModelsMaleMiddle AgedOdds RatioPatient SelectionPredictive Value of TestsQuality ImprovementRetrospective StudiesRisk AssessmentSeverity of Illness IndexSex FactorsTime FactorsTreatment OutcomeConceptsVentral hernia repairEmergency ventral hernia repairHospital-level factorsHernia repairIndependent predictorsPatient selectionElective operationsWorse outcomesEmergency repairLonger hospital stayNationwide Inpatient SampleMultivariable logistic regressionUnited States populationRace/ethnicityHospital deathHospital staySecondary outcomesElective repairPrimary outcomePayer statusInpatient SamplePatient outcomesVentral herniasElective careGreater oddsOutcomes of abdominoperineal resection for management of anal cancer in HIV-positive patients: a national case review
Leeds IL, Alturki H, Canner JK, Schneider EB, Efron JE, Wick EC, Gearhart SL, Safar B, Fang SH. Outcomes of abdominoperineal resection for management of anal cancer in HIV-positive patients: a national case review. World Journal Of Surgical Oncology 2016, 14: 208. PMID: 27495294, PMCID: PMC4974747, DOI: 10.1186/s12957-016-0970-x.Peer-Reviewed Original ResearchMeSH KeywordsAbdomenAdultAge FactorsAgedAnus NeoplasmsCarcinoma, Squamous CellComorbidityFemaleFollow-Up StudiesHealth Status DisparitiesHIV InfectionsHospital MortalityHumansIncidenceLength of StayMaleMiddle AgedNeoplasm Recurrence, LocalPerineumPostoperative ComplicationsRetrospective StudiesRisk FactorsSalvage TherapyTreatment OutcomeConceptsHIV-positive patientsLength of stayHIV-negative patientsAnal cancerNational Inpatient SampleAbdominoperineal resectionHospitalization costsHIV infectionAnal squamous cell cancerAnal squamous cell carcinomaUtilization Project National Inpatient SampleGreater hospitalization costsWorse postoperative recoveryHIV-positive groupMethodsA retrospective reviewAnal cancer patientsSquamous cell cancerHuman immunodeficiency virusMultivariable logistic regressionSquamous cell carcinomaHospital mortalityHospital stayPerioperative complicationsPostoperative hemorrhagePostoperative outcomes
2015
Understanding Variation in 30-Day Surgical Readmission in the Era of Accountable Care: Effect of the Patient, Surgeon, and Surgical Subspecialties
Gani F, Lucas D, Kim Y, Schneider E, Pawlik T. Understanding Variation in 30-Day Surgical Readmission in the Era of Accountable Care: Effect of the Patient, Surgeon, and Surgical Subspecialties. JAMA Surgery 2015, 150: 1042-1049. PMID: 26244543, DOI: 10.1001/jamasurg.2015.2215.Peer-Reviewed Original ResearchMeSH KeywordsAccountable Care OrganizationsAdultAge FactorsAgedClinical CompetenceComprehensionDatabases, FactualDelivery of Health CareFemaleHumansIncidenceLogistic ModelsMaleMiddle AgedMultivariate AnalysisPatient ReadmissionPhysician's RolePostoperative ComplicationsRetrospective StudiesSex FactorsSocioeconomic FactorsSpecialties, SurgicalSurgical Procedures, OperativeTime FactorsConceptsMajor surgical proceduresSurgical proceduresSurgical subspecialtiesRace/ethnicityPostoperative complicationsEndocrine surgeryAfrican American race/ethnicitySurgeon-level factorsPatient-level factorsTertiary care centerLarge academic medical centerPatient-related factorsSubspecialty levelAdministrative claims dataAcademic medical centerIndividual surgeon levelDifferent surgical subspecialtiesPreoperative comorbiditiesHospital morbidityPatient ageSurgical readmissionsCardiac surgeryTransplant surgeryPayer typeCare centerExplaining the Paradoxical Age-based Racial Disparities in Survival After Trauma
Hicks C, Hashmi Z, Hui X, Velopulos C, Efron D, Schneider E, Cooper L, Haut E, Cornwell E, Haider A. Explaining the Paradoxical Age-based Racial Disparities in Survival After Trauma. Annals Of Surgery 2015, 262: 179-183. PMID: 24979610, DOI: 10.1097/sla.0000000000000809.Peer-Reviewed Original ResearchConceptsOlder black patientsYoung black patientsYoung white patientsBlack patientsWhite patientsBlack trauma patientsRacial disparitiesTrauma patientsInjury severityClinical Modification diagnosis codesOlder white patientsPatients 65 yearsOverall injury severityMechanism of injuryNationwide Inpatient SampleHead injury severityOlder patientsIncreased oddsComorbid conditionsSurvival outcomesNinth RevisionInsurance statusAdjusted oddsDiagnosis codesInpatient SampleOutcomes of trauma care at centers treating a higher proportion of older patients
Zafar S, Obirieze A, Schneider E, Hashmi Z, Scott V, Greene W, Efron D, MacKenzie E, Cornwell E, Haider A. Outcomes of trauma care at centers treating a higher proportion of older patients. Journal Of Trauma And Acute Care Surgery 2015, 78: 852-859. PMID: 25742246, DOI: 10.1097/ta.0000000000000557.Peer-Reviewed Original ResearchConceptsOlder trauma patientsOlder patientsTrauma patientsTrauma centerLevel 2 trauma centerMultivariate logistic regression modelRisk-adjusted mortality ratioYoung adultsGeriatric trauma patientsAdult trauma patientsBurden of injuryLength of stayObserved-expected ratioTrauma center performanceHigher proportionLogistic regression modelsGeriatric traumaYounger patientsTrauma deathsMortality ratioTrauma visitsTrauma careEpidemiologic studiesPatientsBetter outcomes
2014
Association Between Race and Age in Survival After Trauma
Hicks C, Hashmi Z, Velopulos C, Efron D, Schneider E, Haut E, Cornwell E, Haider A. Association Between Race and Age in Survival After Trauma. JAMA Surgery 2014, 149: 642-647. PMID: 24871941, PMCID: PMC5995325, DOI: 10.1001/jamasurg.2014.166.Peer-Reviewed Original ResearchConceptsCharlson Comorbidity IndexPatients 65 yearsOlder patientsBlack patientsInjury severityComorbidity indexRacial disparitiesWhite patientsOdds ratioBetter outcomesCharlson Comorbidity Index scoreClinical Modification diagnosis codesLogistic regressionComorbidity Index scoreOlder black patientsOlder white patientsYoung black patientsYoung white patientsMost older patientsIntent of injuryNationwide Inpatient SampleMultivariable logistic regressionUnadjusted odds ratioUnivariable logistic regressionHead injury severity
2013
Venous Thromboembolism After Trauma: When Do Children Become Adults?
Van Arendonk K, Schneider E, Haider A, Colombani P, Stewart F, Haut E. Venous Thromboembolism After Trauma: When Do Children Become Adults? JAMA Surgery 2013, 148: 1123-1130. PMID: 24173244, DOI: 10.1001/jamasurg.2013.3558.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAge FactorsChildChild, PreschoolCohort StudiesConfidence IntervalsDatabases, FactualFemaleHospitalizationHumansIncidenceInfantMaleOdds RatioPrognosisRetrospective StudiesRisk AssessmentTrauma CentersTrauma Severity IndicesTreatment OutcomeUnited StatesVenous ThromboembolismWounds and InjuriesYoung AdultConceptsRisk of VTEVenous thromboembolismPediatric traumaTrauma centerStandardized guidelinesNational Trauma Data BankMultivariable logistic regression modelDiagnosis of VTENational standardized guidelinesOdds of VTEPatients 16 yearsPatients 21 yearsVenous thromboembolism prophylaxisVTE risk factorsPatients 12 yearsTrauma Data BankUS trauma centersAge 16 yearsCentral line placementAge 13 yearsLogistic regression modelsThromboembolism prophylaxisVTE prophylaxisPatient ageYounger patientsProvider versus patient factors impacting hospital length of stay after pancreaticoduodenectomy
Schneider E, Hyder O, Wolfgang C, Dodson R, Haider A, Herman J, Pawlik T. Provider versus patient factors impacting hospital length of stay after pancreaticoduodenectomy. Surgery 2013, 154: 152-161. PMID: 23889945, DOI: 10.1016/j.surg.2013.03.013.Peer-Reviewed Original ResearchConceptsDuration of stayHigh-volume hospitalsHigh-volume surgeonsHospital volumeMedian durationPD volumeMedian annual surgeon volumeAnnual hospital volumeAnnual surgeon volumePatient-level factorsNationwide Inpatient SampleCost-saving implicationsLow surgeonComorbid illnessesHospital lengthPerioperative outcomesVolume hospitalsHospital durationOlder patientsPatient ageMedian ageNonclinical factorsPatient factorsSurgeon volumePD patientsInfluence of gender on outcomes after thoracic endovascular aneurysm repair
Arnaoutakis G, Schneider E, Arnaoutakis D, Black J, Lum Y, Perler B, Freischlag J, Abularrage C. Influence of gender on outcomes after thoracic endovascular aneurysm repair. Journal Of Vascular Surgery 2013, 59: 45-51. PMID: 23896176, DOI: 10.1016/j.jvs.2013.06.058.Peer-Reviewed Original ResearchMeSH KeywordsAge FactorsAgedAortic Aneurysm, ThoracicChi-Square DistributionDatabases, FactualEmergenciesEndovascular ProceduresFemaleHumansIliac ArteryLinear ModelsLogistic ModelsMaleMultivariate AnalysisOdds RatioPostoperative ComplicationsRegistriesRetrospective StudiesRisk FactorsSex FactorsTime FactorsTreatment OutcomeUnited StatesConceptsIliac artery exposureNonruptured thoracic aortic aneurysmsAortic aneurysm repairThoracic aortic aneurysmAneurysm repairArtery exposureUnadjusted mortalityMultivariable analysisAortic aneurysmFemale genderSurgeons National Surgical Quality Improvement Program databaseNational Surgical Quality Improvement Program databaseRisk-adjusted generalized linear modelsEndovascular abdominal aortic aneurysm repairQuality Improvement Program databaseAbdominal aortic aneurysm repairEndovascular aortic aneurysm repairACS-NSQIP databaseImprovement Program databasePrimary outcome measureEndovascular aneurysm repairHigh mortality rateHospital lengthPostoperative complicationsTransfusion rateState-by-state variation in emergency versus elective colon resections: Room for improvement
Obirieze A, Kisat M, Hicks C, Oyetunji T, Schneider E, Gaskin D, Haut E, Efron D, Cornwell E, Haider A. State-by-state variation in emergency versus elective colon resections: Room for improvement. Journal Of Trauma And Acute Care Surgery 2013, 74: 1286. PMID: 23609280, PMCID: PMC3645918, DOI: 10.1097/ta.0b013e31828b8478.Peer-Reviewed Original ResearchConceptsElective colon resectionColon surgeryColon resectionOdds ratioElective colon surgeryEmergency colon surgeryNationwide Inpatient SampleFinal study cohortElective surgical proceduresDischarge-level weightsSubstantial state variationsElective colectomyEmergency colectomyHospital factorsAdult patientsStudy cohortEmergent proceduresInpatient SampleNational averageColon operationsUnadjusted proportionRetrospective analysisSurgical proceduresEmergency proceduresColectomyTrends in Robot-assisted Laparoscopic Pyeloplasty in Pediatric Patients
Monn M, Bahler C, Schneider E, Whittam B, Misseri R, Rink R, Sundaram C. Trends in Robot-assisted Laparoscopic Pyeloplasty in Pediatric Patients. Urology 2013, 81: 1336-1341. PMID: 23522294, DOI: 10.1016/j.urology.2013.01.025.Peer-Reviewed Original ResearchConceptsRobotic-assisted laparoscopic pyeloplastyNationwide Inpatient SampleLaparoscopic pyeloplastyPediatric pyeloplastyPediatric robotic-assisted laparoscopic pyeloplastyMultiple logistic regressionYears of agePediatric patientsInpatient SampleInvasive techniquesPyeloplastyAge-related trendsRobotic pyeloplastyNational ratesLogistic regressionPatientsOlder childrenRobotic techniquesRobotic assistanceIncidenceTotal numberOverall increaseYears
2012
BRAF V600E mutation and Its Association with Clinicopathological Features of Papillary Thyroid Cancer: A Meta-Analysis
Li C, Lee K, Schneider E, Zeiger M. BRAF V600E mutation and Its Association with Clinicopathological Features of Papillary Thyroid Cancer: A Meta-Analysis. The Journal Of Clinical Endocrinology & Metabolism 2012, 97: 4559-4570. PMID: 23055546, PMCID: PMC3513529, DOI: 10.1210/jc.2012-2104.Peer-Reviewed Original ResearchMeSH KeywordsAge FactorsAmino Acid SubstitutionCarcinomaCarcinoma, PapillaryFemaleGenetic Association StudiesGenetic Predisposition to DiseaseGlutamic AcidHumansLymphatic MetastasisMaleMutation, MissenseProto-Oncogene Proteins B-rafSex CharacteristicsThyroid Cancer, PapillaryThyroid NeoplasmsTumor BurdenValineConceptsLymph node metastasisPapillary thyroid cancerLymph node dissectionTall cell variant papillary thyroid cancerRoutine central lymph node dissectionCentral lymph node dissectionClassic papillary thyroid cancerNode dissectionBRAF V600E mutationClinicopathological featuresAbsence of capsuleTumor sizeMale genderOdds ratioThyroid cancerBRAF mutationsMantel-Haenszel pooled odds ratiosPresence of LNMV600E mutationStudy-specific odds ratiosManagement of patientsPooled odds ratioAggressive clinicopathological featuresImportant clinical decisionsConsecutive patients
2011
Congestive Heart Failure and Chronic Obstructive Pulmonary Disease Predict Poor Surgical Outcomes in Older Adults Undergoing Elective Diverticulitis Surgery
Sheer AJ, Heckman JE, Schneider EB, Wu AW, Segal JB, Feinberg R, Lidor AO. Congestive Heart Failure and Chronic Obstructive Pulmonary Disease Predict Poor Surgical Outcomes in Older Adults Undergoing Elective Diverticulitis Surgery. Diseases Of The Colon & Rectum 2011, 54: 1430-1437. PMID: 21979190, DOI: 10.1097/dcr.0b013e31822c4e85.Peer-Reviewed Original ResearchConceptsChronic obstructive pulmonary diseaseCongestive heart failureObstructive pulmonary diseaseComorbid congestive heart failureHeart failurePulmonary diseaseHospital mortalityPostoperative complicationsOlder patientsElective surgeryOutcome measuresOlder adultsReview (MEDPAR) Inpatient FilesShock/sepsisRetrospective cohort studyPostoperative complication rateSecondary outcome measuresBenefits of surgeryPoor surgical outcomesPrimary outcome measureSubgroup of patientsAge 65 yearsLeft colon resectionCommon medical conditionsMedicare Provider AnalysisOlder patients with diverticulitis have low recurrence rates and rarely need surgery
Lidor AO, Segal JB, Wu AW, Yu Q, Feinberg R, Schneider EB. Older patients with diverticulitis have low recurrence rates and rarely need surgery. Surgery 2011, 150: 146-153. PMID: 21801956, DOI: 10.1016/j.surg.2011.05.006.Peer-Reviewed Original ResearchConceptsOlder patientsRecurrent episodesLow recurrence rateNumber of recurrencesMedicare Provider AnalysisCohort studyElderly patientsOperative interventionPatient agePrimary outcomeDiverticulitis recurrenceIncident cohortBenign courseFurther recurrenceMean ageRecurrence rateInitial careOutpatient filesInpatient careDiverticulitisFirst presentationPatientsSurgeryRecurrenceConservative approach