2019
Socioeconomically Distressed Communities Index independently predicts major adverse limb events after infrainguinal bypass in a national cohort
Hawkins R, Mehaffey J, Charles E, Kern J, Schneider E, Tracci M. Socioeconomically Distressed Communities Index independently predicts major adverse limb events after infrainguinal bypass in a national cohort. Journal Of Vascular Surgery 2019, 70: 1985-1993.e8. PMID: 31761106, DOI: 10.1016/j.jvs.2019.03.060.Peer-Reviewed Original ResearchConceptsDistressed Communities IndexMajor adverse limb eventsAdverse limb eventsInfrainguinal bypassGraft occlusionIndependent predictorsLimb eventsMajor adverse cardiovascular eventsLong-term maleAdverse cardiovascular eventsOperative risk factorsCritical limb ischemiaMore comorbid diseasesCare-related outcomesHealth care-related outcomesPrior amputationHospital mortalityCardiovascular eventsComorbid diseasesLimb ischemiaSurgical outcomesNational cohortVascular diseaseRisk factorsUnivariate analysis
2017
Thyroid Nodule Diagnostic Markers in the Face of the New NIFTP Category: Time for a Reset?
Sahli Z, Umbricht C, Schneider E, Zeiger M. Thyroid Nodule Diagnostic Markers in the Face of the New NIFTP Category: Time for a Reset? Thyroid 2017, 27: 1393-1399. PMID: 28859553, DOI: 10.1089/thy.2017.0238.Peer-Reviewed Original ResearchConceptsCancer prevalenceSuspicious fine-needle aspiration (FNA) cytologyNon-invasive follicular thyroid neoplasmFine needle aspiration cytologyThyroid cancer prevalencePapillary-like nuclear featuresFollicular thyroid neoplasmPrecancerous lesionsDifferential diagnosisAspiration cytologyLatter diagnosisClinical validityThyroid neoplasmsOriginal validation studyMolecular panelDiagnostic markerMolecular testsNuclear featuresNIFTP reclassificationPrevalence
2016
Validation of international trauma scoring systems in urban trauma centres in India
Roy N, Gerdin M, Schneider E, Veetil D, Khajanchi M, Kumar V, Saha M, Dharap S, Gupta A, Tomson G, von Schreeb J. Validation of international trauma scoring systems in urban trauma centres in India. Injury 2016, 47: 2459-2464. PMID: 27667119, DOI: 10.1016/j.injury.2016.09.027.Peer-Reviewed Original ResearchConceptsInjury Severity ScoreTrauma Injury Severity ScoreKampala Trauma ScoreTrauma patientsCasualty departmentPhysiological scoreTrauma centerSeverity scoreProspective multi-centre observational cohort studyMulti-center observational cohort studyInjury Severity Scale scoreAdult trauma patientsObservational cohort studySeverity Scale scoreUrban trauma centerHistory of injuryIncome country settingsMiddle-income country settingsHospital mortalityLate mortalityUrban Indian settingAdult patientsCohort studyInpatient mortalityPhysiologic scoreThirty-day re-admission after traumatic brain injury: Results from MarketScan®
Canner J, Giuliano K, Gani F, Schneider E. Thirty-day re-admission after traumatic brain injury: Results from MarketScan®. Brain Injury 2016, 30: 1570-1575. PMID: 27589200, DOI: 10.1080/02699052.2016.1199898.Peer-Reviewed Original ResearchConceptsTraumatic brain injuryPrimary diagnosisBrain injuryHead Abbreviated Injury ScoreCharacteristics of patientsCommon primary diagnosisAbbreviated Injury ScoreRe-admission ratesInpatient rehabilitation facilityIndex dischargeMore comorbiditiesConcurrent injuriesIndex hospitalizationInjury scoreDischarge planningThirty-dayRehabilitation facilityPsychiatric disordersGreater oddsPatientsElucidate causesAge 65InjuryDiagnosisMarketScanFrailty predicts risk of life-threatening complications and mortality after pancreatic resections
Augustin T, Burstein M, Schneider E, Morris-Stiff G, Wey J, Chalikonda S, Walsh R. Frailty predicts risk of life-threatening complications and mortality after pancreatic resections. Surgery 2016, 160: 987-996. PMID: 27545992, DOI: 10.1016/j.surg.2016.07.010.Peer-Reviewed Original ResearchMeSH KeywordsAge FactorsAgedCause of DeathComorbidityDatabases, FactualFemaleFrail ElderlyHumansLogistic ModelsMaleMiddle AgedMultivariate AnalysisPancreatectomyPancreatic NeoplasmsPancreaticoduodenectomyPostoperative ComplicationsPredictive Value of TestsRetrospective StudiesRisk AssessmentROC CurveSeverity of Illness IndexSex FactorsSurvival AnalysisTreatment OutcomeConceptsNational Surgical Quality Improvement ProjectSurgical Quality Improvement ProjectGrade 4 complicationsFrailty indexQuality improvement projectGreater body mass indexDistal pancreatectomy patientsModified Frailty IndexOutcomes of pancreatoduodenectomyLow serum albuminLife-threatening complicationsPre-operative optimizationEffect of frailtySelection of patientsBody mass indexDegree of frailtyGreater weight lossImprovement projectIntermediate frailtyNonfrail patientsConsideration of frailtyDistal pancreatectomyFrail patientsOperative riskPancreatectomy patientsPredictors of emergency ventral hernia repair: Targets to improve patient access and guide patient selection for elective repair
Wolf LL, Scott JW, Zogg CK, Havens JM, Schneider EB, Smink DS, Salim A, Haider AH. Predictors of emergency ventral hernia repair: Targets to improve patient access and guide patient selection for elective repair. Surgery 2016, 160: 1379-1391. PMID: 27542434, DOI: 10.1016/j.surg.2016.06.027.Peer-Reviewed Original ResearchMeSH KeywordsAdultAge FactorsAgedAged, 80 and overConfidence IntervalsDatabases, FactualElective Surgical ProceduresEmergenciesFemaleFollow-Up StudiesHealth Services AccessibilityHernia, VentralHerniorrhaphyHospital MortalityHumansInsurance CoverageLogistic ModelsMaleMiddle AgedOdds RatioPatient SelectionPredictive Value of TestsQuality ImprovementRetrospective StudiesRisk AssessmentSeverity of Illness IndexSex FactorsTime FactorsTreatment OutcomeConceptsVentral hernia repairEmergency ventral hernia repairHospital-level factorsHernia repairIndependent predictorsPatient selectionElective operationsWorse outcomesEmergency repairLonger hospital stayNationwide Inpatient SampleMultivariable logistic regressionUnited States populationRace/ethnicityHospital deathHospital staySecondary outcomesElective repairPrimary outcomePayer statusInpatient SamplePatient outcomesVentral herniasElective careGreater odds
2015
A modified Kampala trauma score (KTS) effectively predicts mortality in trauma patients
Weeks S, Stevens K, Haider A, Efron D, Haut E, MacKenzie E, Schneider E. A modified Kampala trauma score (KTS) effectively predicts mortality in trauma patients. Injury 2015, 47: 125-129. PMID: 26256783, DOI: 10.1016/j.injury.2015.07.004.Peer-Reviewed Original ResearchConceptsNew Injury Severity ScoreInjury Severity ScoreKampala Trauma ScoreTrauma patientsSeverity scoreTrauma ScorePhysiologic measuresMortality predictionNon-trauma center hospitalsSeverity scoring toolsPre-hospital intubationCenter HospitalInjury scoreAnatomical injuryMortality riskLevel IInjury severityRespiratory ratePhysiologic dataScoring toolOutcome predictionMortalitySignificant predictorsCharacteristic curveSimilar predictive abilityHow Do Liquid-Based Preparations of Thyroid Fine-Needle Aspiration Compare with Conventional Smears? An Analysis of 5475 Specimens
Nagarajan N, Schneider EB, Ali SZ, Zeiger MA, Olson MT. How Do Liquid-Based Preparations of Thyroid Fine-Needle Aspiration Compare with Conventional Smears? An Analysis of 5475 Specimens. Thyroid 2015, 25: 308-313. PMID: 25420135, DOI: 10.1089/thy.2014.0394.Peer-Reviewed Original ResearchConceptsFine-needle aspirationLiquid-based preparationsLBP casesConventional smearsBenign diagnosisThyroid nodulesMalignant diagnosisHistology diagnosisAspirated materialClinical databaseSuspicious categoryCS casesInitial evaluationInadequate samplesDiagnosisNodule sizePatientsSecond reviewDiagnostic frequencySmearsInadequate rateHigher proportionLower proportionPivotal roleNodules
2014
Development of a duplex-derived velocity risk prediction model of disease progression in patients with moderate asymptomatic carotid artery stenosis
Hicks CW, Canner JK, Arhuidese I, Glebova NO, Schneider E, Qazi U, Perler B, Malas MB. Development of a duplex-derived velocity risk prediction model of disease progression in patients with moderate asymptomatic carotid artery stenosis. Journal Of Vascular Surgery 2014, 60: 1585-1592. PMID: 25238724, DOI: 10.1016/j.jvs.2014.08.056.Peer-Reviewed Original ResearchMeSH KeywordsAgedAged, 80 and overArea Under CurveAsymptomatic DiseasesBlood Flow VelocityCarotid Artery, CommonCarotid Artery, InternalCarotid StenosisChi-Square DistributionDecision Support TechniquesDisease ProgressionFemaleHumansMaleMiddle AgedMultivariate AnalysisPredictive Value of TestsProportional Hazards ModelsRegional Blood FlowRetrospective StudiesRisk AssessmentRisk FactorsROC CurveTime FactorsUltrasonography, Doppler, DuplexConceptsAsymptomatic carotid artery stenosisICA/CCA ratioCarotid artery stenosisInternal carotid arteryDisease progressionEnd-diastolic velocityPeak systolic velocityRisk prediction modelCCA ratioArtery stenosisSystolic velocityRisk factorsInitial peak systolic velocityProportional hazards regression modelsHigh-risk patientsRisk of progressionRisk-stratify patientsHazards regression modelsSignificant independent predictorsICA/CCACharacteristic curve analysisClinical prediction modelCarotid artery ratioIndependent predictorsDuplex imagingFunctional recovery after moderate/severe traumatic brain injury
Schneider E, Sur S, Raymont V, Duckworth J, Kowalski R, Efron D, Hui X, Selvarajah S, Hambridge H, Stevens R. Functional recovery after moderate/severe traumatic brain injury. Neurology 2014, 82: 1636-1642. PMID: 24759845, PMCID: PMC4211893, DOI: 10.1212/wnl.0000000000000379.Peer-Reviewed Original ResearchMeSH KeywordsAgedBrain InjuriesCognition DisordersCohort StudiesDisability EvaluationEducational StatusFemaleHumansMaleMiddle AgedPredictive Value of TestsRecovery of FunctionConceptsSevere traumatic brain injuryTraumatic brain injuryYears of educationBrain injuryDisability Rating Scale scoresProspective multicenter cohortMain outcome measuresRating Scale scoresRobust independent predictorModel Systems databaseDose-response relationshipLogistic regression modelsTBI Model Systems databaseCognitive reserveIndependent predictorsMulticenter cohortPrognostic factorsFunctional recoveryRetrospective studyDuration of educationYears postinjuryOutcome measuresPatientsScale scoreNeural adaptationThe Impact of Molecular Testing on the Surgical Management of Patients with Thyroid Nodules
Aragon Han P, Olson M, Fazeli R, Prescott J, Pai S, Schneider E, Tufano R, Zeiger M. The Impact of Molecular Testing on the Surgical Management of Patients with Thyroid Nodules. Annals Of Surgical Oncology 2014, 21: 1862-1869. PMID: 24522987, DOI: 10.1245/s10434-014-3508-x.Peer-Reviewed Original ResearchMeSH KeywordsAdultAlgorithmsBiopsy, Fine-NeedleDecision Support TechniquesDNA Mutational AnalysisFemaleGene Expression ProfilingGTP PhosphohydrolasesHumansMaleMembrane ProteinsMiddle AgedPredictive Value of TestsProto-Oncogene Proteins B-rafProto-Oncogene Proteins c-retRetrospective StudiesThyroid GlandThyroid NoduleConceptsSurgical managementPreoperative molecular testingMolecular testingThyroid nodulesRET/PTC translocationsPathology analysisMolecular testsSurgical management changesSurgical management decisionsTertiary care centerMajority of patientsSurgical management algorithmJohns Hopkins HospitalPostoperative pathology analysisGene expression classifierUnderwent surgerySurgical consultationThyroid surgeryMethodsClinical informationThyroid surgeonsCare centerFNA diagnosisPatientsSurgical practiceSurgical planning
2013
Increased risk of pneumonia among ventilated patients with traumatic brain injury: every day counts!
Hui X, Haider A, Hashmi Z, Rushing A, Dhiman N, Scott V, Selvarajah S, Haut E, Efron D, Schneider E. Increased risk of pneumonia among ventilated patients with traumatic brain injury: every day counts! Journal Of Surgical Research 2013, 184: 438-443. PMID: 23816243, DOI: 10.1016/j.jss.2013.05.072.Peer-Reviewed Original ResearchConceptsTraumatic brain injuryRisk of pneumoniaMechanical ventilationCause pneumoniaAIS scoreBrain injuryGlasgow Coma Scale motor scoreNational Trauma Data Bank 2007Days of MVICDMAP-90 softwareDevelopment of pneumoniaInjury Scale scoreScale motor scoreRisk of VAPApproximate relative riskVentilator independenceComorbidity scoreHospital lengthNeurologic impairmentMotor scoresVentilated patientsInjury factorsInsurance statusInjury typePneumonia cases
2012
Should the IDC-9 Trauma Mortality Prediction Model become the new paradigm for benchmarking trauma outcomes?
Haider A, Villegas C, Saleem T, Efron D, Stevens K, Oyetunji T, Cornwell E, Bowman S, Haack S, Baker S, Schneider E. Should the IDC-9 Trauma Mortality Prediction Model become the new paradigm for benchmarking trauma outcomes? Journal Of Trauma And Acute Care Surgery 2012, 72: 1695-1701. PMID: 22695443, DOI: 10.1097/ta.0b013e318256a010.Peer-Reviewed Original ResearchMeSH KeywordsAdultAgedBenchmarkingCohort StudiesDatabases, FactualFemaleHospital MortalityHumansInternational Classification of DiseasesMaleMiddle AgedModels, StatisticalPredictive Value of TestsRetrospective StudiesSensitivity and SpecificityTrauma Severity IndicesTreatment OutcomeUnited StatesWounds and InjuriesYoung AdultConceptsInjury Severity ScoreNew ISSMortality prediction modelTrauma Mortality Prediction ModelTrauma outcomesInjury typeInjury severityNational Trauma Data BankNew Injury Severity ScoreInjury severity indicesMortality prediction abilityTrauma Data BankTrauma registry dataCrude mortality rateReceiver operator characteristic curveDRG International ClassificationOperator characteristic curveHospital mortalitySeverity scoreSubgroup analysisRegistry dataRetrospective analysisOutcome measuresPrognostic studiesInternational Classification
2011
Congestive Heart Failure and Chronic Obstructive Pulmonary Disease Predict Poor Surgical Outcomes in Older Adults Undergoing Elective Diverticulitis Surgery
Sheer AJ, Heckman JE, Schneider EB, Wu AW, Segal JB, Feinberg R, Lidor AO. Congestive Heart Failure and Chronic Obstructive Pulmonary Disease Predict Poor Surgical Outcomes in Older Adults Undergoing Elective Diverticulitis Surgery. Diseases Of The Colon & Rectum 2011, 54: 1430-1437. PMID: 21979190, DOI: 10.1097/dcr.0b013e31822c4e85.Peer-Reviewed Original ResearchConceptsChronic obstructive pulmonary diseaseCongestive heart failureObstructive pulmonary diseaseComorbid congestive heart failureHeart failurePulmonary diseaseHospital mortalityPostoperative complicationsOlder patientsElective surgeryOutcome measuresOlder adultsReview (MEDPAR) Inpatient FilesShock/sepsisRetrospective cohort studyPostoperative complication rateSecondary outcome measuresBenefits of surgeryPoor surgical outcomesPrimary outcome measureSubgroup of patientsAge 65 yearsLeft colon resectionCommon medical conditionsMedicare Provider AnalysisPredictors of Positive Head CT Scan and Neurosurgical Procedures After Minor Head Trauma
Kisat M, Zafar S, Latif A, Villegas C, Efron D, Stevens K, Haut E, Schneider E, Zafar H, Haider A. Predictors of Positive Head CT Scan and Neurosurgical Procedures After Minor Head Trauma. Journal Of Surgical Research 2011, 173: 31-37. PMID: 21872271, PMCID: PMC3684145, DOI: 10.1016/j.jss.2011.04.059.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultAge FactorsAgedAged, 80 and overBlack or African AmericanCraniocerebral TraumaFemaleHeadHumansLogistic ModelsMaleMiddle AgedNeurosurgical ProceduresPredictive Value of TestsRetrospective StudiesSex FactorsTomography, X-Ray ComputedTrauma Severity IndicesTreatment OutcomeWhite PeopleYoung AdultConceptsPositive head CT scanNormal Glasgow Coma ScaleGlasgow Coma ScaleHead CT scanMinor head injuryBlunt head injuryHead injuryCT scanNeurosurgical proceduresInjury characteristicsPositive findingsNational Trauma Data BankInjury-specific characteristicsMinor head traumaMechanism of injuryTrauma Data BankHistory of fallsMultivariate logistic regressionAdult patientsOlder patientsComa ScaleMale patientsPrimary outcomeHead traumaMale gender