2019
Socioeconomically Distressed Communities Index independently predicts major adverse limb events after infrainguinal bypass in a national cohort
Hawkins R, Mehaffey J, Charles E, Kern J, Schneider E, Tracci M. Socioeconomically Distressed Communities Index independently predicts major adverse limb events after infrainguinal bypass in a national cohort. Journal Of Vascular Surgery 2019, 70: 1985-1993.e8. PMID: 31761106, DOI: 10.1016/j.jvs.2019.03.060.Peer-Reviewed Original ResearchConceptsDistressed Communities IndexMajor adverse limb eventsAdverse limb eventsInfrainguinal bypassGraft occlusionIndependent predictorsLimb eventsMajor adverse cardiovascular eventsLong-term maleAdverse cardiovascular eventsOperative risk factorsCritical limb ischemiaMore comorbid diseasesCare-related outcomesHealth care-related outcomesPrior amputationHospital mortalityCardiovascular eventsComorbid diseasesLimb ischemiaSurgical outcomesNational cohortVascular diseaseRisk factorsUnivariate analysisEffect of Travel Time for Thyroid Surgery on Treatment Cost and Morbidity
Ramirez A, Schneider E, Mehaffey J, Zeiger M, Hanks J, Smith P. Effect of Travel Time for Thyroid Surgery on Treatment Cost and Morbidity. The American Surgeon 2019, 85: 949-955. PMID: 31638505, DOI: 10.1177/000313481908500934.Peer-Reviewed Original ResearchConceptsHigh-volume centersThyroid surgeryPrimary outcomeHospital costsSingle high-volume centerMedian operative timeHealth care utilizationCertain patient populationsMultivariable regression modelingPatient's home addressHome addressPostoperative morbidityACS-NSQIPOperative timePatient populationUninsured statusThyroid diseaseEndocrine surgeryMorbidity riskThyroid proceduresSurgical careTime-related differencesPatient differencesDisease processPatients
2018
Association Between Age and Patient‐Reported Changes in Voice and Swallowing After Thyroidectomy
Sahli Z, Canner J, Najjar O, Schneider E, Prescott J, Russell J, Tufano R, Zeiger M, Mathur A. Association Between Age and Patient‐Reported Changes in Voice and Swallowing After Thyroidectomy. The Laryngoscope 2018, 129: 519-524. PMID: 30194684, PMCID: PMC6344315, DOI: 10.1002/lary.27297.Peer-Reviewed Original ResearchConceptsSwallowing changesSwallowing alterationsRisk factorsIntraoperative recurrent laryngeal nerve monitoringIntact recurrent laryngeal nerveRecurrent laryngeal nerve monitoringPatient-reported voiceGastroesophageal reflux diseaseAdditional prospective studiesLaryngeal nerve monitoringRecurrent laryngeal nervePresence of malignancyImpact of ageInstitutional review boardIntact RLNReflux diseaseRLN injuryTotal thyroidectomyFrailty statusPatient ageConsecutive patientsFrailty indexRetrospective reviewLaryngeal nerveNerve monitoringManagement outcomes of diverticulitis and colitis in patients with active cancer
Horwood C, Wisler J, Byrd S, Woodling K, Schneider E, Rushing A. Management outcomes of diverticulitis and colitis in patients with active cancer. Surgery 2018, 164: 350-353. PMID: 29801733, DOI: 10.1016/j.surg.2018.03.010.Peer-Reviewed Original ResearchMeSH KeywordsAdultAgedColitisDigestive System Surgical ProceduresDiverticulitis, ColonicFemaleHumansMaleMiddle AgedNeoplasmsOhioPeritonitisPostoperative ComplicationsRetrospective StudiesConceptsActive cancer diagnosisColonic emergenciesActive cancerNonoperative managementIntensive care unit admissionEmergent general surgeryCare unit admissionPreoperative risk factorsCancer diagnosisNon-operative managementCancer patient populationIntensive care unitNonoperative groupNonoperative patientsUnit admissionPostoperative complicationsCare unitColonic pathologyOperative groupSurgery consultOperative managementPatient populationCancer DatabaseRisk factorsGeneral surgeryBilateral mastectomies: can a co-surgeon technique offer improvements over the single-surgeon method?
Mallory MA, Tarabanis C, Schneider E, Nimbkar S, Golshan M. Bilateral mastectomies: can a co-surgeon technique offer improvements over the single-surgeon method? Breast Cancer Research And Treatment 2018, 170: 641-646. PMID: 29687179, PMCID: PMC6026038, DOI: 10.1007/s10549-018-4794-y.Peer-Reviewed Original ResearchMeSH KeywordsAdultAgedBreast NeoplasmsFemaleHumansMammaplastyMastectomyMiddle AgedNeoplasm StagingOperative TimeOutcome Assessment, Health CarePostoperative ComplicationsRetrospective StudiesSurgeonsConceptsSingle surgeon's techniqueTotal breast weightAxillary procedureComplication rateOperative timeBreast weightChi-square testSS cohortTBW patientsMultivariate linear regression modelPatient ageUnilateral mastectomyBRCA statusBM casesAverage durationComplicationsDemographic characteristicsMastectomyPatientsT-testLinear regression modelsCohortRegression modelsBM proceduresBMAssociation of Parathyroid Hormone Level With Postthyroidectomy Hypocalcemia: A Systematic Review
Mathur A, Nagarajan N, Kahan S, Schneider E, Zeiger M. Association of Parathyroid Hormone Level With Postthyroidectomy Hypocalcemia: A Systematic Review. JAMA Surgery 2018, 153: 69-76. PMID: 29167863, DOI: 10.1001/jamasurg.2017.3398.Peer-Reviewed Original ResearchMeSH KeywordsBiomarkersHumansHypocalcemiaParathyroid HormonePostoperative ComplicationsPreoperative PeriodSensitivity and SpecificityThyroidectomyConceptsParathyroid hormone levelsPTH thresholdPTH levelsPrognostic significancePostthyroidectomy hypocalcemiaHormone levelsSystematic reviewTrue prognostic significanceAdditional prospective studiesEarly predictive markerDevelopment of hypocalcemiaFull-text publicationsLaboratory drawsTotal thyroidectomyCalcium supplementationCochrane DatabaseParathyroid hormoneProspective studyPredictive markerIndependent reviewersHypocalcemiaStudy characteristicsThyroidectomyHypocalcaemiaInitial search
2017
One‐Hour Postoperative Parathyroid Hormone Levels Do Not Reliably Predict Hypocalcemia After Thyroidectomy
Sahli Z, Najafian A, Kahan S, Schneider E, Zeiger M, Mathur A. One‐Hour Postoperative Parathyroid Hormone Levels Do Not Reliably Predict Hypocalcemia After Thyroidectomy. World Journal Of Surgery 2017, 42: 2128-2133. PMID: 29290070, PMCID: PMC5991999, DOI: 10.1007/s00268-017-4444-2.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultAgedAged, 80 and overFemaleHumansHypocalcemiaMaleMiddle AgedParathyroid HormonePostoperative ComplicationsPostoperative PeriodProspective StudiesThyroidectomyYoung AdultConceptsPostoperative parathyroid hormone levelsPg/mLParathyroid hormone levelsPostoperative PTHPTH levelsBiochemical hypocalcemiaTotal thyroidectomyCalcium supplementationProspective studyHormone levelsAppropriate calcium supplementationDefinitive study designPostoperative biochemical hypocalcemiaAdditional prospective studiesNormal PTH levelsPTH decreaseCompletion thyroidectomyConsecutive patientsSerum calciumLow PTHPTH 1HypocalcemiaIRB approvalThyroidectomyPTHFinancial Impact of Acute Kidney Injury After Cardiac Operations in the United States
Alshaikh H, Katz N, Gani F, Nagarajan N, Canner J, Kacker S, Najjar P, Higgins R, Schneider E. Financial Impact of Acute Kidney Injury After Cardiac Operations in the United States. The Annals Of Thoracic Surgery 2017, 105: 469-475. PMID: 29275828, DOI: 10.1016/j.athoracsur.2017.10.053.Peer-Reviewed Original ResearchConceptsAcute kidney injuryIndex hospitalization costsTotal index hospitalization costsIndex hospital costsCardiac operationsHospitalization costsKidney injuryDevelopment of AKISubstantial health care cost savingsClinical Modification diagnosis codesHealth care cost savingsMajor cardiac operationsCoronary artery bypassChronic renal failureNationwide Inpatient SampleMajor cardiac proceduresLong-term treatmentArtery bypassRenal failureValve replacementReplacement patientsAvoidable complicationsCardiac proceduresPatient morbidityDiagnosis codesObesity and its implications for morbidity and mortality after cholecystectomy: A matched NSQIP analysis
Augustin T, Moslim M, Brethauer S, Aminian A, Kroh M, Schneider E, Walsh R. Obesity and its implications for morbidity and mortality after cholecystectomy: A matched NSQIP analysis. The American Journal Of Surgery 2017, 213: 539-543. PMID: 28237044, DOI: 10.1016/j.amjsurg.2016.11.037.Peer-Reviewed Original ResearchConceptsAcute cholecystitisClavien 4 complicationsSO patientsNSQIP AnalysisSuper obesityOpen surgeryNon-obese patientsObese patientsSerious morbidityLaparoscopic surgeryCholecystectomyPatientsSurgeryMorbidityComplicationsObesityChronicMortalityAggressive recommendationsRiskCholecystitisComorbidities
2016
Benefits of Bowel Preparation Beyond Surgical Site Infection
Althumairi A, Canner J, Pawlik T, Schneider E, Nagarajan N, Safar B, Efron J. Benefits of Bowel Preparation Beyond Surgical Site Infection. Annals Of Surgery 2016, 264: 1051-1057. PMID: 26727098, DOI: 10.1097/sla.0000000000001576.Peer-Reviewed Original ResearchConceptsOral antibiotic bowel preparationMechanical bowel preparationSurgical site infectionBowel preparationElective colectomyPostoperative complicationsAnastomotic leakSite infectionIncidence of SSIReduction of SSIOrgan space surgical site infectionDeep surgical site infectionParticipant Use Data FileReduced surgical site infectionsSpace surgical site infectionSuperficial surgical site infectionAntibiotic bowel preparationPostoperative ileusPostoperative outcomesSSI incidenceColectomy casesSeptic shockWound dehiscenceLower incidenceStudy populationImplementation of a Comprehensive Post-Discharge Venous Thromboembolism Prophylaxis Program for Abdominal and Pelvic Surgery Patients
Najjar PA, Madenci AL, Zogg CK, Schneider EB, Dankers CA, Pimentel MT, Chabria AS, Goldberg JE, Sharma G, Piazza G, Bleday R, Orgill DP, Kachalia A. Implementation of a Comprehensive Post-Discharge Venous Thromboembolism Prophylaxis Program for Abdominal and Pelvic Surgery Patients. Journal Of The American College Of Surgeons 2016, 223: 804-813. PMID: 27693288, PMCID: PMC6309555, DOI: 10.1016/j.jamcollsurg.2016.09.010.Peer-Reviewed Original ResearchConceptsPost-intervention cohortPre-intervention cohortInflammatory bowel diseaseVenous thromboembolismProphylaxis programAbdominal surgeryBowel diseasePost-discharge VTE ratesVenous thromboembolism prophylaxis programBedside medication deliveryInpatient venous thromboembolismInstitutional American CollegeSymptomatic venous thromboembolismPrimary end pointMajor abdominal surgeryVTE prevention programSingle-institution retrospectiveSurgeons NSQIP datasetPost-intervention analysisProphylactic anticoagulationVTE prophylaxisVTE ratesVTE eventsNSQIP datasetRisk patientsA comparison of trends in operative approach and postoperative outcomes for colorectal cancer surgery
Addae J, Gani F, Fang S, Wick E, Althumairi A, Efron J, Canner J, Euhus D, Schneider E. A comparison of trends in operative approach and postoperative outcomes for colorectal cancer surgery. Journal Of Surgical Research 2016, 208: 111-120. PMID: 27993198, DOI: 10.1016/j.jss.2016.09.019.Peer-Reviewed Original ResearchConceptsLength of stayShorter LOSColorectal cancer surgerySurgical approachColorectal surgeryPostoperative morbidityPostoperative outcomesCancer surgeryOpen surgeryInvasive surgeryOpen colorectal surgeryInvasive colorectal surgeryTime of surgeryCochrane-Armitage testNationwide Inpatient SampleRobotic colorectal surgeryHigher mean costCRC surgeryPerioperative outcomesPostoperative complicationsInpatient SampleOpen procedureOperative approachMean costSurgeryInfluence of Specialty Training and Trainee Involvement on Perioperative Outcomes of Esophagectomy
Khoushhal Z, Canner J, Schneider E, Stem M, Haut E, Mungo B, Lidor A, Molena D. Influence of Specialty Training and Trainee Involvement on Perioperative Outcomes of Esophagectomy. The Annals Of Thoracic Surgery 2016, 102: 1829-1836. PMID: 27570158, DOI: 10.1016/j.athoracsur.2016.06.025.Peer-Reviewed Original ResearchMeSH KeywordsAgedEsophagectomyFemaleGeneral SurgeryHumansLength of StayMaleMiddle AgedPostoperative ComplicationsQuality ImprovementRetrospective StudiesThoracic SurgeryTreatment OutcomeUnited StatesConceptsVolume-outcome relationshipGeneral surgeonsHospital stayCardiothoracic surgeonsTrainee involvementTransthoracic approachNational Surgical Quality Improvement Program databaseSurgeons National Surgical Quality Improvement Program databaseQuality Improvement Program databaseOutcomes of esophagectomyImprovement Program databaseLonger hospital stayShorter hospital staySurgeon volume-outcome relationshipUnplanned intubationOverall morbidityPerioperative outcomesPostoperative outcomesSecondary outcomesDischarge destinationPrimary outcomeSerious morbidityCTS patientsSurgeon specialtyWound infectionFrailty predicts risk of life-threatening complications and mortality after pancreatic resections
Augustin T, Burstein M, Schneider E, Morris-Stiff G, Wey J, Chalikonda S, Walsh R. Frailty predicts risk of life-threatening complications and mortality after pancreatic resections. Surgery 2016, 160: 987-996. PMID: 27545992, DOI: 10.1016/j.surg.2016.07.010.Peer-Reviewed Original ResearchMeSH KeywordsAge FactorsAgedCause of DeathComorbidityDatabases, FactualFemaleFrail ElderlyHumansLogistic ModelsMaleMiddle AgedMultivariate AnalysisPancreatectomyPancreatic NeoplasmsPancreaticoduodenectomyPostoperative ComplicationsPredictive Value of TestsRetrospective StudiesRisk AssessmentROC CurveSeverity of Illness IndexSex FactorsSurvival AnalysisTreatment OutcomeConceptsNational Surgical Quality Improvement ProjectSurgical Quality Improvement ProjectGrade 4 complicationsFrailty indexQuality improvement projectGreater body mass indexDistal pancreatectomy patientsModified Frailty IndexOutcomes of pancreatoduodenectomyLow serum albuminLife-threatening complicationsPre-operative optimizationEffect of frailtySelection of patientsBody mass indexDegree of frailtyGreater weight lossImprovement projectIntermediate frailtyNonfrail patientsConsideration of frailtyDistal pancreatectomyFrail patientsOperative riskPancreatectomy patientsOutcomes of abdominoperineal resection for management of anal cancer in HIV-positive patients: a national case review
Leeds IL, Alturki H, Canner JK, Schneider EB, Efron JE, Wick EC, Gearhart SL, Safar B, Fang SH. Outcomes of abdominoperineal resection for management of anal cancer in HIV-positive patients: a national case review. World Journal Of Surgical Oncology 2016, 14: 208. PMID: 27495294, PMCID: PMC4974747, DOI: 10.1186/s12957-016-0970-x.Peer-Reviewed Original ResearchMeSH KeywordsAbdomenAdultAge FactorsAgedAnus NeoplasmsCarcinoma, Squamous CellComorbidityFemaleFollow-Up StudiesHealth Status DisparitiesHIV InfectionsHospital MortalityHumansIncidenceLength of StayMaleMiddle AgedNeoplasm Recurrence, LocalPerineumPostoperative ComplicationsRetrospective StudiesRisk FactorsSalvage TherapyTreatment OutcomeConceptsHIV-positive patientsLength of stayHIV-negative patientsAnal cancerNational Inpatient SampleAbdominoperineal resectionHospitalization costsHIV infectionAnal squamous cell cancerAnal squamous cell carcinomaUtilization Project National Inpatient SampleGreater hospitalization costsWorse postoperative recoveryHIV-positive groupMethodsA retrospective reviewAnal cancer patientsSquamous cell cancerHuman immunodeficiency virusMultivariable logistic regressionSquamous cell carcinomaHospital mortalityHospital stayPerioperative complicationsPostoperative hemorrhagePostoperative outcomesRethinking Priorities
Zogg CK, Najjar P, Diaz A, Zogg DL, Tsai TC, Rose JA, Scott JW, Gani F, Alshaikh H, Nagarajan N, Canner JK, Schneider EB, Goldberg JE, Haider AH. Rethinking Priorities. Annals Of Surgery 2016, 264: 312-322. PMID: 26501705, DOI: 10.1097/sla.0000000000001511.Peer-Reviewed Original ResearchConceptsElective colectomyPrimary diagnosisNationwide Inpatient Sample dataIncremental costBenign colonic neoplasmsSystem-based complicationsCost of complicationsSurgical quality improvement initiativesIncremental hospital costsLong-term treatmentQuality improvement initiativesExperienced complicationsInfectious complicationsCardiovascular complicationsComplication groupDiverticular diseaseOpen resectionAdult patientsFrequent diagnosisColonic neoplasmsHospital costsOperative techniqueColectomyComplicationsHealthcare costsHospital readmission after multiple major operative procedures among patients with employer provided health insurance
Kim Y, Gani F, Canner J, Margonis G, Makary M, Schneider E, Pawlik T. Hospital readmission after multiple major operative procedures among patients with employer provided health insurance. Surgery 2016, 160: 178-190. PMID: 27085686, DOI: 10.1016/j.surg.2016.01.025.Peer-Reviewed Original ResearchConceptsMultiple operative proceduresDays of dischargeMajor operative proceduresOperative procedureSingle operative procedureIndex dischargeLate readmissionHospital readmissionMultivariable logistic regression analysisHigher preoperative comorbidityLate hospital readmissionLogistic regression analysisDuration of stayPreoperative comorbiditiesPostoperative complicationsPostoperative dischargeMarketScan databaseMultivariable analysisOverall incidenceAbdominal proceduresSame hospitalRisk factorsReadmissionCardiovascular proceduresGreater oddsA novel score to estimate the risk of pneumonia after cardiac surgery
Kilic A, Ohkuma R, Grimm J, Magruder J, Sussman M, Schneider E, Whitman G. A novel score to estimate the risk of pneumonia after cardiac surgery. Journal Of Thoracic And Cardiovascular Surgery 2016, 151: 1415-1421. PMID: 27085620, DOI: 10.1016/j.jtcvs.2015.12.049.Peer-Reviewed Original ResearchMeSH KeywordsAge DistributionAgedCardiac Surgical ProceduresCardiopulmonary BypassCohort StudiesFemaleHumansIncidenceMaleMiddle AgedMultivariate AnalysisPneumoniaPostoperative ComplicationsRegression AnalysisRetrospective StudiesRisk FactorsSeverity of Illness IndexSex DistributionSurvival RateUnited StatesConceptsCardiac surgeryPostoperative pneumoniaRisk scoreValidation cohortRisk factorsMultivariable modelRate of pneumoniaRisk of pneumoniaSingle-institution databaseSignificant risk factorsComposite scoreIntraoperative predictorsPerioperative managementPrimary outcomeTraining cohortPneumoniaSurgeryNovel scorePreventative interventionsCohortOverall rateScoresPatientsSignificant correlationRegression analysis
2015
Understanding Variation in 30-Day Surgical Readmission in the Era of Accountable Care: Effect of the Patient, Surgeon, and Surgical Subspecialties
Gani F, Lucas D, Kim Y, Schneider E, Pawlik T. Understanding Variation in 30-Day Surgical Readmission in the Era of Accountable Care: Effect of the Patient, Surgeon, and Surgical Subspecialties. JAMA Surgery 2015, 150: 1042-1049. PMID: 26244543, DOI: 10.1001/jamasurg.2015.2215.Peer-Reviewed Original ResearchMeSH KeywordsAccountable Care OrganizationsAdultAge FactorsAgedClinical CompetenceComprehensionDatabases, FactualDelivery of Health CareFemaleHumansIncidenceLogistic ModelsMaleMiddle AgedMultivariate AnalysisPatient ReadmissionPhysician's RolePostoperative ComplicationsRetrospective StudiesSex FactorsSocioeconomic FactorsSpecialties, SurgicalSurgical Procedures, OperativeTime FactorsConceptsMajor surgical proceduresSurgical proceduresSurgical subspecialtiesRace/ethnicityPostoperative complicationsEndocrine surgeryAfrican American race/ethnicitySurgeon-level factorsPatient-level factorsTertiary care centerLarge academic medical centerPatient-related factorsSubspecialty levelAdministrative claims dataAcademic medical centerIndividual surgeon levelDifferent surgical subspecialtiesPreoperative comorbiditiesHospital morbidityPatient ageSurgical readmissionsCardiac surgeryTransplant surgeryPayer typeCare centerEffect of Mandatory Centers of Excellence Designation on Demographic Characteristics of Patients Who Undergo Bariatric Surgery
Bae J, Shade J, Abraham A, Abraham B, Peterson L, Schneider EB, Magnuson TH, Schweitzer MA, Steele KE. Effect of Mandatory Centers of Excellence Designation on Demographic Characteristics of Patients Who Undergo Bariatric Surgery. JAMA Surgery 2015, 150: 644-648. PMID: 25993654, DOI: 10.1001/jamasurg.2015.74.Peer-Reviewed Original ResearchConceptsProportion of patientsPercentage of patientsBariatric surgerySociodemographic characteristicsIncome quartilePatients' sociodemographic characteristicsBariatric surgical patientsBariatric surgical proceduresNational Inpatient SampleHighest income quartileCenters of excellenceLowest income quartileSurgical patientsFemale patientsInpatient SampleSurgical proceduresMAIN OUTCOMEPatientsSurgeryPatient accessLogistic regressionPrivate insurancePatient safetyMedicaid ServicesExcellence designation