2016
Association of BRAFV600E Mutation and MicroRNA Expression with Central Lymph Node Metastases in Papillary Thyroid Cancer: A Prospective Study from Four Endocrine Surgery Centers
Han PA, Kim HS, Cho S, Fazeli R, Najafian A, Khawaja H, McAlexander M, Dy B, Sorensen M, Aronova A, Sebo TJ, Giordano TJ, Fahey TJ, Thompson GB, Gauger PG, Somervell H, Bishop JA, Eshleman JR, Schneider EB, Witwer KW, Umbricht CB, Zeiger MA. Association of BRAFV600E Mutation and MicroRNA Expression with Central Lymph Node Metastases in Papillary Thyroid Cancer: A Prospective Study from Four Endocrine Surgery Centers. Thyroid 2016, 26: 532-542. PMID: 26950846, PMCID: PMC4827320, DOI: 10.1089/thy.2015.0378.Peer-Reviewed Original ResearchConceptsCentral lymph node metastasisCentral lymph node dissectionMultivariable logistic regression analysisPapillary thyroid cancerProphylactic central lymph node dissectionLogistic regression analysisLymph node dissectionAggressive clinicopathologic featuresLymph node metastasisEndocrine surgery centersStand-alone markerClinicopathologic featuresMiR-146bNode dissectionIndependent predictorsNode metastasisMiR-222Surgery centersThyroid cancerProphylactic lymph node dissectionRegression analysisIndividual prognostic markersOnly preoperative variablesNode-negative casesMicroRNA expressionA novel score to estimate the risk of pneumonia after cardiac surgery
Kilic A, Ohkuma R, Grimm J, Magruder J, Sussman M, Schneider E, Whitman G. A novel score to estimate the risk of pneumonia after cardiac surgery. Journal Of Thoracic And Cardiovascular Surgery 2016, 151: 1415-1421. PMID: 27085620, DOI: 10.1016/j.jtcvs.2015.12.049.Peer-Reviewed Original ResearchMeSH KeywordsAge DistributionAgedCardiac Surgical ProceduresCardiopulmonary BypassCohort StudiesFemaleHumansIncidenceMaleMiddle AgedMultivariate AnalysisPneumoniaPostoperative ComplicationsRegression AnalysisRetrospective StudiesRisk FactorsSeverity of Illness IndexSex DistributionSurvival RateUnited StatesConceptsCardiac surgeryPostoperative pneumoniaRisk scoreValidation cohortRisk factorsMultivariable modelRate of pneumoniaRisk of pneumoniaSingle-institution databaseSignificant risk factorsComposite scoreIntraoperative predictorsPerioperative managementPrimary outcomeTraining cohortPneumoniaSurgeryNovel scorePreventative interventionsCohortOverall rateScoresPatientsSignificant correlationRegression analysis
2013
Predictors of outcome in acute encephalitis
Thakur K, Motta M, Asemota A, Kirsch H, Benavides D, Schneider E, McArthur J, Geocadin R, Venkatesan A. Predictors of outcome in acute encephalitis. Neurology 2013, 81: 793-800. PMID: 23892708, PMCID: PMC3908458, DOI: 10.1212/wnl.0b013e3182a2cc6d.Peer-Reviewed Original ResearchConceptsMultivariate logistic regression analysisPredictors of outcomeStatus epilepticusLogistic regression analysisCerebral edemaHospital dischargePoor outcomeJohns Hopkins Bayview Medical CenterPredictors of deathFurther prospective studiesIntensive care unitJohns Hopkins HospitalRegression analysisIntubation requirementAutoimmune etiologyAcute encephalitisAggressive managementVentilator supportMedian ageCare unitViral encephalitisProspective studyEncephalitis casesUnknown causeRetrospective analysis