Association of variants in innate immune genes with asthma and eczema
Sharma S, Poon A, Himes BE, Lasky‐Su J, Sordillo JE, Belanger K, Milton DK, Bracken MB, Triche EW, Leaderer BP, Gold DR, Litonjua AA. Association of variants in innate immune genes with asthma and eczema. Pediatric Allergy And Immunology 2011, 23: 315-323. PMID: 22192168, PMCID: PMC3412627, DOI: 10.1111/j.1399-3038.2011.01243.x.Peer-Reviewed Original ResearchConceptsInnate immune genesPathogenesis of asthmaInnate immune pathwaysSingle nucleotide polymorphismsAsthma StudyImmune genesImmune pathwaysChildhood Asthma StudyPolymorphisms of genesAssociation of variantsChildhood asthmaEczema riskAsthmaCase controlEczemaImmune variantsAdditional single nucleotide polymorphismsBayesian network analysisHome allergensScreening algorithmDifferent genetic determinantsTop single nucleotide polymorphismsPathogenesisMultiple comparisonsDisease susceptibilityAssociation of maternal anemia with increased wheeze and asthma in children
Triche EW, Lundsberg LS, Wickner PG, Belanger K, Leaderer BP, Bracken MB. Association of maternal anemia with increased wheeze and asthma in children. Annals Of Allergy Asthma & Immunology 2011, 106: 131-139.e1. PMID: 21277514, PMCID: PMC3073499, DOI: 10.1016/j.anai.2010.11.007.Peer-Reviewed Original ResearchConceptsMaternal anemiaEarly-onset transientRespiratory health outcomesChildren of womenOffspring of mothersRespiratory disease developmentChildren of mothersYears of ageEarly childhoodAge 3Delivery hospitalizationsRecurrent wheezeCurrent asthmaAsthma diagnosisChildhood asthmaInfant wheezeMaternal nutritionRespiratory healthWheezeAsthmaAnemiaHealth outcomesPregnancyAnemia diagnosisMicronutrient status