2010
Benign tumors and tumor-like lesions of the gallbladder and extrahepatic biliary tract
Van Patten K, Jain D. Benign tumors and tumor-like lesions of the gallbladder and extrahepatic biliary tract. Diagnostic Histopathology 2010, 16: 371-379. DOI: 10.1016/j.mpdhp.2010.06.001.Peer-Reviewed Original ResearchTumor-like lesionsBenign tumorsChronic cholecystitisTypes of metaplasiaExtrahepatic bile ductExtrahepatic biliary tractSoft tissue counterpartsSurgical pathology laboratoryBiliary typeBiliary tractBile ductNeurogenic lesionsMesenchymal tumorsEpithelial tumorsBenign lesionsLesionsGallbladderTumorsTissue counterpartsPathology laboratoryWrong diagnosisCholecystitisMalignancyCommon specimensVast majorityMalignant tumours of gallbladder and extrahepatic bile ducts
Flood T, Jain D, Marginean E. Malignant tumours of gallbladder and extrahepatic bile ducts. Diagnostic Histopathology 2010, 16: 360-370. DOI: 10.1016/j.mpdhp.2010.06.003.Peer-Reviewed Original ResearchExtrahepatic bile duct cancerExtrahepatic bile ductBile ductGallbladder cancerBiliary tract neoplasmsBile duct cancerStage of diseaseUseful prognostic indicatorManagement of cancerDuct cancerOlder patientsAggressive courseFavorable prognosisClinical presentationHistologic typePancreaticobiliary typeChronic inflammationHistologic featuresPoor prognosisHistologic gradePrognostic indicatorGeographic predilectionHistologic variantsBiliary epitheliumMalignant tumors
2009
Diagnostic use of cytokeratins, CD34, and neuronal cell adhesion molecule staining in focal nodular hyperplasia and hepatic adenoma
Ahmad I, Iyer A, Marginean CE, Yeh MM, Ferrell L, Qin L, Bifulco CB, Jain D. Diagnostic use of cytokeratins, CD34, and neuronal cell adhesion molecule staining in focal nodular hyperplasia and hepatic adenoma. Human Pathology 2009, 40: 726-734. PMID: 19157505, DOI: 10.1016/j.humpath.2008.10.018.Peer-Reviewed Original ResearchConceptsTelangiectatic focal nodular hyperplasiaFocal nodular hyperplasia casesFocal nodular hyperplasiaNeuronal cell adhesion moleculeHepatic adenomaNodular hyperplasiaCytokeratin 7Cytokeratin 19Hyperplasia casesNeedle biopsyCell adhesion moleculeBile ductAdhesion moleculesCD34 stainCytokeratin 7 stainingCorresponding resection specimensDiagnostic useParaffin-embedded sectionsDistinct staining patternsProspective studyResected specimensHistologic featuresResection specimenResection specimensCorresponding resections
2008
Different cytokeratin and neuronal cell adhesion molecule staining patterns in focal nodular hyperplasia and hepatic adenoma and their significance
Iyer A, Robert ME, Bifulco CB, Salem RR, Jain D. Different cytokeratin and neuronal cell adhesion molecule staining patterns in focal nodular hyperplasia and hepatic adenoma and their significance. Human Pathology 2008, 39: 1370-1377. PMID: 18602664, PMCID: PMC3738023, DOI: 10.1016/j.humpath.2008.01.015.Peer-Reviewed Original ResearchConceptsFocal nodular hyperplasiaNeuronal cell adhesion moleculeHepatic adenomaNodular hyperplasiaCell adhesion moleculeCytokeratin 7Cytokeratin 19Biliary epitheliumProgenitor/stem cellsAdhesion moleculesTelangiectatic focal nodular hyperplasiaCytokeratin 7 stainsStem cellsRare positivityAbnormal perfusionBile ductHepatocellular carcinomaStrong positivityHepatic endotheliumImmunohistochemical analysisModerate stainingFibrous septaDifferent cytokeratinsHyperplasiaAdenomasBiliary and Pancreatic Dysgenesis in Mice Harboring a Mutation in Pkhd1
Gallagher AR, Esquivel EL, Briere TS, Tian X, Mitobe M, Menezes LF, Markowitz GS, Jain D, Onuchic LF, Somlo S. Biliary and Pancreatic Dysgenesis in Mice Harboring a Mutation in Pkhd1. American Journal Of Pathology 2008, 172: 417-429. PMID: 18202188, PMCID: PMC2312372, DOI: 10.2353/ajpath.2008.070381.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsBile DuctsBiliary TractBlotting, SouthernBlotting, WesternCiliaDisease Models, AnimalHumansImmunohistochemistryIn Situ HybridizationKidney Tubules, ProximalLiver DiseasesMiceMice, Mutant StrainsMutationPancreatic DiseasesPolycystic Kidney, Autosomal RecessiveReceptors, Cell SurfaceReverse Transcriptase Polymerase Chain ReactionConceptsPolycystic kidney diseaseAutosomal recessive polycystic kidney diseaseRecessive polycystic kidney diseaseKidney diseaseMouse modelCommon bile duct dilationBile duct dilationBile duct proliferationAutosomal dominant polycystic kidney diseaseProgressive cyst formationDistal nephron segmentsDominant polycystic kidney diseaseExtrahepatic manifestationsDuct dilationBiliary tractPeriportal fibrosisDuct proliferationBile ductFibrocystic diseaseOrthologous modelPancreatic cystsProximal tubulesMice harboringSusceptibility of tissuesNephron segments
2007
Intraductal Papillary Cholangiocarcinoma Associated With von Meyenberg Complexes: A Case Report
Neto AG, Dainiak C, Qin L, Salem RR, Jain D. Intraductal Papillary Cholangiocarcinoma Associated With von Meyenberg Complexes: A Case Report. Digestive Diseases And Sciences 2007, 52: 2643-2645. PMID: 17394067, DOI: 10.1007/s10620-007-9777-5.Peer-Reviewed Original ResearchConceptsIntraductal papillary cholangiocarcinomaVon Meyenberg complexesColicky right upper quadrant painRight upper quadrant painBile duct neoplasmsFine fibrovascular coresGastric foveolar typeUpper quadrant painBiliary colicPapillary cholangiocarcinomaQuadrant painLeft hepatectomyBile ductLeft lobeCase reportFibrovascular coresPapillary frondsFoveolar typePeribiliary glandsRare caseLiver parenchymaRare formImaging studiesEnglish literatureTumors