2015
Assessing ovarian response: antral follicle count versus anti-Müllerian hormone
Fleming R, Seifer DB, Frattarelli JL, Ruman J. Assessing ovarian response: antral follicle count versus anti-Müllerian hormone. Reproductive BioMedicine Online 2015, 31: 486-496. PMID: 26283017, DOI: 10.1016/j.rbmo.2015.06.015.Peer-Reviewed Original ResearchConceptsAntral follicle countAnti-Müllerian hormoneAMH levelsOvarian reserveFollicle countOvarian responseFollicle numberPredictive valueSerum anti-Müllerian hormoneGood predictive valuePersonalization of treatmentGold standard biomarkerOvarian stimulationExogenous gonadotrophinsMenstrual cyclePoor responseHormone biomarkersOocyte numberUltrasound biomarkersBiomarkersAmerican SocietyGood responseSame ageHormoneStimulation
1994
Dehydroepiandrosterone sulfate and anovulation increase serum inhibin and affect follicular function during administration of gonadotropins
Haning RV, Hua JJ, Hackett RJ, Wheeler CA, Frishman GN, Seifer DB, Dahl CA, Burger HG. Dehydroepiandrosterone sulfate and anovulation increase serum inhibin and affect follicular function during administration of gonadotropins. The Journal Of Clinical Endocrinology & Metabolism 1994, 78: 145-149. PMID: 8288697, DOI: 10.1210/jcem.78.1.8288697.Peer-Reviewed Original ResearchConceptsNumber of oocytesAnovulatory subjectsSerum inhibinAnovulatory ovariesSerum concentrationsNormal subjectsSerum DS concentrationSerum inhibin concentrationsAdministration of gonadotropinSecretion of inhibinResidual serum samplesDuration of treatmentAnovulatory patientsGonadotropin therapyInhibin concentrationsInhibin secretionPatient ageFertilization cyclesGonadotropin treatmentLH dosesFollicular functionHCG treatmentInhibinAverage durationSerum samples
1992
Flow cytometric analysis of deoxyribonucleic acid in human granulosa cells as a function of chronological age and ovulation induction regimen
Seifer DB, Honig J, Penzias AS, Lavy G, Nadkarni PM, Jones EE, DeCherney AH, Flynn SD. Flow cytometric analysis of deoxyribonucleic acid in human granulosa cells as a function of chronological age and ovulation induction regimen. The Journal Of Clinical Endocrinology & Metabolism 1992, 75: 636-640. PMID: 1639962, DOI: 10.1210/jcem.75.2.1639962.Peer-Reviewed Original ResearchConceptsHuman menopausal gonadotropinOvulation induction regimenGreater proliferative indexInduction regimenLeuprolide acetateProliferative indexGranulosa cellsGroup IGroup IIGroup IIIAmpules of hMGFunction of ageFlow cytometryDay of hCGProspective cohort studyGroup of patientsHuman granulosa cellsChronological ageMenopausal gonadotropinCohort studyOvulation inductionSerum FSHSignificant independent influenceOutcome measuresWomen's ageBaseline ovarian cysts do not affect clinical response to controlled ovarian hyperstimulation for in vitro fertilization**Presented at the 47th Annual Meeting of The American Fertility Society, Orlando, Florida, October 21 to 24, 1991.
Penzias A, Jones E, Seifer D, Grifo J, Thatcher S, DeCherney A. Baseline ovarian cysts do not affect clinical response to controlled ovarian hyperstimulation for in vitro fertilization**Presented at the 47th Annual Meeting of The American Fertility Society, Orlando, Florida, October 21 to 24, 1991. Fertility And Sterility 1992, 57: 1017-1021. PMID: 1572468, DOI: 10.1016/s0015-0282(16)55019-5.Peer-Reviewed Original ResearchConceptsBaseline ovarian cystsNumber of folliclesOvarian cystsOvarian hyperstimulationIVF cyclesClinical responseStimulation regimenBaseline E2 levelBaseline serum estradiolCycle cancellation ratePeak serum E2Vitro Fertilization ProgramAmerican Fertility SocietyNumber of oocytesSerum E2Serum estradiolNumber of cystsCycle outcomeE2 levelsCyst sizeFertility SocietySuch cystsCancellation rateYale University SchoolOwn control