2018
Risk of prematurity and infant morbidity and mortality by maternal fertility status and plurality
Luke B, Brown MB, Wantman E, Seifer DB, Sparks AT, Lin PC, Doody KJ, Van Voorhis BJ, Spector LG. Risk of prematurity and infant morbidity and mortality by maternal fertility status and plurality. Journal Of Assisted Reproduction And Genetics 2018, 36: 121-138. PMID: 30328574, PMCID: PMC6338589, DOI: 10.1007/s10815-018-1333-z.Peer-Reviewed Original ResearchConceptsMaternal fertility statusRisk of prematurityIVF groupIVF pregnanciesDonor oocytesPlacental complicationsGreater riskInfant deathThawed embryosResultsThe study populationConfidence intervalsFertilization pregnanciesIVF infantsNICU admissionGestational diabetesInfant morbidityOdds ratioInfertility treatmentDeath certificatesLive birthsStudy populationPregnancyInfant's birthPrematurityOocyte source
2015
Prognostic indicators of assisted reproduction technology outcomes of cycles with ultralow serum antimüllerian hormone: a multivariate analysis of over 5,000 autologous cycles from the Society for Assisted Reproductive Technology Clinic Outcome Reporting System database for 2012–2013
Seifer DB, Tal O, Wantman E, Edul P, Baker VL. Prognostic indicators of assisted reproduction technology outcomes of cycles with ultralow serum antimüllerian hormone: a multivariate analysis of over 5,000 autologous cycles from the Society for Assisted Reproductive Technology Clinic Outcome Reporting System database for 2012–2013. Fertility And Sterility 2015, 105: 385-393.e3. PMID: 26515380, DOI: 10.1016/j.fertnstert.2015.10.004.Peer-Reviewed Original ResearchMeSH KeywordsAdultAnti-Mullerian HormoneBiomarkersCryopreservationDatabases, FactualEmbryo TransferFemaleFertilityFertilization in VitroHumansInfertilityLinear ModelsLive BirthLogistic ModelsMiddle AgedMultivariate AnalysisOocyte RetrievalPatient SelectionPregnancyPregnancy RatePregnancy, MultipleReproductive Techniques, AssistedRetrospective StudiesRisk AssessmentRisk FactorsTreatment OutcomeYoung AdultConceptsLive birth rateAntimüllerian hormoneCancellation rateAMH levelsAssisted Reproductive Technology Clinic Outcome Reporting System databaseAssisted reproduction technology (ART) outcomesEmbryo cryopreservation ratesSerum antimüllerian hormoneTotal cancellation rateMultiple birth ratesReporting System databaseCycle startAutologous cyclesClinical pregnancyCycle cancellationPrognostic factorsAMH valuesFresh cyclesCycle outcomePrognostic indicatorAMH concentrationsRetrospective analysisMAIN OUTCOMEEmbryo transferMultivariate analysis
2012
Anti-Müllerian hormone as an independent predictor of twin versus singleton pregnancy in fresh cycles
Tal R, Seifer DB, Khanimov M, Schwartz E, Grazi RV, Malter HE. Anti-Müllerian hormone as an independent predictor of twin versus singleton pregnancy in fresh cycles. Reproductive BioMedicine Online 2012, 26: 360-367. PMID: 23419793, DOI: 10.1016/j.rbmo.2012.12.002.Peer-Reviewed Original ResearchConceptsAnti-Müllerian hormoneSerum AMH concentrationsFresh non-donor cyclesSerum anti-Müllerian hormoneNon-donor cyclesTwin pregnanciesAMH concentrationsSingleton pregnanciesIndependent predictorsIncidence of twinsFresh cyclesMultiple pregnanciesFertility clinicsPossible predictorsEgg reserveQuantitative ovarian responseLive birth rateChance of pregnancyROC curve analysisSignificant predictive abilityMultiple gestationsOvarian responseTwin gestationsRetrospective studyPregnancy rate
2002
Practice patterns among board-certified reproductive endocrinologists regarding high-order multiple gestations: a united states national survey.
Hock DL, Seifer DB, Kontopoulos E, Ananth CV. Practice patterns among board-certified reproductive endocrinologists regarding high-order multiple gestations: a united states national survey. Obstetrics And Gynecology 2002, 99: 763-70. PMID: 11978285, DOI: 10.1016/s0029-7844(02)01950-6.Peer-Reviewed Original ResearchMeSH KeywordsCounselingEndocrinologyFemaleFertilization in VitroHealth SurveysHumansInformed ConsentInsemination, ArtificialOvarian FollicleOvulation InductionPractice Patterns, Physicians'PregnancyPregnancy Reduction, MultifetalPregnancy, High-RiskPregnancy, MultipleReproductive MedicineRisk FactorsSuperovulationSurveys and QuestionnairesUnited StatesConceptsHigh-order multiple gestationsMultiple gestationsOverall pregnancy rateReproductive endocrinologistsIntrauterine inseminationOvulation inductionPractice patternsBoard-certified reproductive endocrinologistsHigher-order pregnanciesCurrent practice managementSurvey response ratePregnancy rateMost physiciansGestationResponse ratePractitioner demographicsEndocrinologistsInformed consentSequelaeIncidencePractice managementRiskInseminationInductionQuestionnaire
1998
Predicting Probabilities of Pregnancy and Multiple Gestation From In Vitro Fertilization—A New Model
WHEELER C, COLE B, FRISHMAN G, SEIFER D, LOVEGREEN S, HACKETT R. Predicting Probabilities of Pregnancy and Multiple Gestation From In Vitro Fertilization—A New Model. Obstetrics And Gynecology 1998, 91: 696-700. DOI: 10.1097/00006250-199805000-00010.Peer-Reviewed Original ResearchMeSH KeywordsAdultEmbryo TransferFemaleFertilization in VitroHumansLogistic ModelsMiddle AgedModels, StatisticalPregnancyPregnancy, MultipleConceptsMultiple gestationsProbability of pregnancyEmbryo scoreNumber of embryosThird implantationFertilization cyclesInfant HospitalIVF programVitro FertilizationEmbryo transferPregnancySecond implantationLogistic regressionPatient-specific informationGestationP2/P1Embryo scoringHospitalScoresAgeImplantationBest predictorP3/P2PatientsPredicting probabilities of pregnancy and multiple gestation from in vitro fertilization--a new model.
Wheeler C, Cole B, Frishman G, Seifer D, Lovegreen S, Hackett R. Predicting probabilities of pregnancy and multiple gestation from in vitro fertilization--a new model. Obstetrics And Gynecology 1998, 91: 696-700. PMID: 9572213, DOI: 10.1016/s0029-7844(98)00008-8.Peer-Reviewed Original ResearchMeSH KeywordsAdultEmbryo TransferFemaleFertilization in VitroHumansLogistic ModelsMiddle AgedModels, StatisticalPregnancyPregnancy, MultipleConceptsIn vitro fertilizationEmbryo scoreMultiple gestationsProbability of pregnancyIn vitro fertilization programDistribution of pregnanciesEmbryo transferInfant hospitalizationPregnancyGestationIncreasing ageLogistic regressionPatient-specific informationScoresImplantationEmbryosPredicted probabilityAgePatientsInfants
1996
Effects of fetal number and multifetal reduction on length of in vitro fertilization pregnancies.
Haning RV, Seifer DB, Wheeler CA, Frishman GN, Silver H, Pierce DJ. Effects of fetal number and multifetal reduction on length of in vitro fertilization pregnancies. Obstetrics And Gynecology 1996, 87: 964-8. PMID: 8649707, DOI: 10.1016/0029-7844(96)00059-2.Peer-Reviewed Original ResearchConceptsDuration of gestationMultifetal reductionFertilization pregnanciesMultifetal pregnancy reductionIVF pregnanciesTriplet pregnanciesMultiple gestationsMean gestationIVF programPregnancy reductionViable fetusesMore fetusesFetal numberPregnancyGestationWeeksFetusesRegression analysisDurationSpontaneous reductionNatural causesTwinsWomenRelaxin secretion in in vitro fertilization pregnancies
Haning R, Goldsmith L, Seifer D, Wheeler C, Frishman G, Sarmento J, Weiss G. Relaxin secretion in in vitro fertilization pregnancies. American Journal Of Obstetrics And Gynecology 1996, 174: 233-240. PMID: 8572013, DOI: 10.1016/s0002-9378(96)70400-3.Peer-Reviewed Original ResearchConceptsHuman chorionic gonadotropinSecretion of relaxinChorionic gonadotropinCorpora luteaSerum estradiolSerum relaxinFunctional statusHuman chorionic gonadotropin (hCG) injectionOvarian hyperstimulation syndromeSerum of womenSecretion of steroidsSerum relaxin concentrationsFertilization pregnanciesHyperstimulation syndromePremature deliveryMultiple gestationsGonadotropin injectionRelaxin secretionMore injectionsRelaxin concentrationsProgesterone concentrationsMultiple linear regression analysisPregnancyGonadotropinSteroid concentrations
1995
Maternal and neonatal morbidity associated with in vitro fertilization
Tallo CP, Vohr B, Oh W, Rubin LP, Seifer DB, Haning RV. Maternal and neonatal morbidity associated with in vitro fertilization. The Journal Of Pediatrics 1995, 127: 794-800. PMID: 7472838, DOI: 10.1016/s0022-3476(95)70175-3.Peer-Reviewed Original ResearchConceptsLow birth weightNeonatal morbidityBirth weightIVF infantsIVF mothersMultiple gestationsControl subjectsLower mean birth weightMore pregnancy-induced hypertensionSingle large teaching hospitalContinuous positive airway pressureMore daysMore perinatal complicationsPregnancy-induced hypertensionPositive airway pressureMean birth weightRespiratory distress syndromePatent ductus arteriosusCase-control studyLarge teaching hospitalDate of deliveryIVF pregnanciesPreterm deliveryAirway pressureLabor induction