Featured Publications
Cumulative live birth rates with autologous oocytes plateau with fewer number of cycles for each year of age > 42
Seifer D, Wang S, Frankfurter D. Cumulative live birth rates with autologous oocytes plateau with fewer number of cycles for each year of age > 42. Reproductive Biology And Endocrinology 2023, 21: 94. PMID: 37872609, PMCID: PMC10591412, DOI: 10.1186/s12958-023-01144-z.Peer-Reviewed Original ResearchConceptsCumulative live birth rateLive birth rateART cyclesBirth rateDesignRetrospective cohort studyPrior ART cyclesUse of ICSIEtiology of infertilityNumber of oocytesAge categoriesSART CORS databaseYears of ageTreatment cycle numberRace/ethnicityAutologous cyclesResultsBetween 2014Ovarian reserveCohort studyBlastocyst transferWomen 46Women 42Age 45Live birthsMAIN OUTCOMEPhysician expectations
2021
Disparities in ART Live Birth and Cumulative Live Birth Outcomes for Hispanic and Asian Women Compared to White Non-Hispanic Women
Kotlyar AM, Simsek B, Seifer DB. Disparities in ART Live Birth and Cumulative Live Birth Outcomes for Hispanic and Asian Women Compared to White Non-Hispanic Women. Journal Of Clinical Medicine 2021, 10: 2615. PMID: 34198545, PMCID: PMC8231797, DOI: 10.3390/jcm10122615.Peer-Reviewed Original ResearchCumulative live birth rateNon-Hispanic womenLive birthsWNH womenAsian womenWhite non-Hispanic womenART live birthsCycles of ARTHistory of endometriosisIndependent prognostic factorLive birth rateReproductive technology outcomesEtiology of infertilityLive birth outcomesMultivariate logistic regressionUse of ICSINumber of embryosNulliparous womenPrognostic factorsBirth outcomesAsian patientsART cyclesART treatmentART statusMember clinicsThe Impact of Intracytoplasmic Sperm Injection in Non-Male Factor Infertility—A Critical Review
Glenn TL, Kotlyar AM, Seifer DB. The Impact of Intracytoplasmic Sperm Injection in Non-Male Factor Infertility—A Critical Review. Journal Of Clinical Medicine 2021, 10: 2616. PMID: 34198564, PMCID: PMC8231975, DOI: 10.3390/jcm10122616.Peer-Reviewed Original ResearchNon-male factor infertilityUse of ICSIIntracytoplasmic sperm injectionTotal fertilization failureFactor infertilityMale factor infertilityFertilization failureSperm injectionSafety of offspringLive birth rateFertilization rateICSI useSurveillance studyInfertilityBirth rateHigh rateInjectionNumerous studiesFailurePatientsIVF
2020
OVERCOMPENSATING? THE USE OF ICSI FOR NON-MALE FACTOR INFERTILITY DOES NOT IMPROVE LIVE BIRTH RATE IN A MATCHED PATIENT POPULATION
Glenn T, Kelk D, Wininger M, Seifer D. OVERCOMPENSATING? THE USE OF ICSI FOR NON-MALE FACTOR INFERTILITY DOES NOT IMPROVE LIVE BIRTH RATE IN A MATCHED PATIENT POPULATION. Fertility And Sterility 2020, 114: e299-e300. DOI: 10.1016/j.fertnstert.2020.08.820.Peer-Reviewed Original Research
2018
Temporal Differences in Utilization of Intracytoplasmic Sperm Injection Among U.S. Regions
Zagadailov P, Hsu A, Stern JE, Seifer DB. Temporal Differences in Utilization of Intracytoplasmic Sperm Injection Among U.S. Regions. Obstetrics And Gynecology 2018, 132: 310-320. PMID: 29995722, DOI: 10.1097/aog.0000000000002730.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultAge FactorsCohort StudiesFemaleFertilization in VitroHumansInfertility, FemaleInfertility, MaleLive BirthMalePregnancyPregnancy RateRetrospective StudiesSperm Injections, IntracytoplasmicTreatment OutcomeUnited StatesUnited States Dept. of Health and Human ServicesYoung AdultConceptsLive birth rateUse of ICSIICSI rateICSI utilizationBirth rateRetrospective cohort studyMale factor infertilityHuman Services (HHS) regionsIntracytoplasmic sperm injectionYears of agePreimplantation genetic testingMale factor diagnosisDepartment of HealthNondonor cyclesCohort studyFertilization cyclesFactor infertilityMale factorSperm injectionMedical indicationsMagnitude of increaseClinicGenetic testingDisease controlICSI
2017
Differences in utilization of Intracytoplasmic sperm injection (ICSI) within human services (HHS) regions and metropolitan megaregions in the U.S.
Zagadailov P, Hsu A, Seifer DB, Stern JE. Differences in utilization of Intracytoplasmic sperm injection (ICSI) within human services (HHS) regions and metropolitan megaregions in the U.S. Reproductive Biology And Endocrinology 2017, 15: 45. PMID: 28606175, PMCID: PMC5469007, DOI: 10.1186/s12958-017-0263-4.Peer-Reviewed Original ResearchConceptsLive birth rateIntracytoplasmic sperm injectionHuman Services (HHS) regionsBirth rateUse of ICSIHigher live birth rateNon-donor cyclesUS practice patternsMale factor infertilityHigh rateDepartment of HealthFactor infertilityMale factorPractice patternsInfertility rateClinic groupSperm injectionHuman service groupsDisease controlWomenClinicInfertilityLower ratesService regionArt differs