2023
AMH independently predicts aneuploidy but not live birth per transfer in IVF PGT-A cycles
Li H, Seifer D, Tal R. AMH independently predicts aneuploidy but not live birth per transfer in IVF PGT-A cycles. Reproductive Biology And Endocrinology 2023, 21: 19. PMID: 36739415, PMCID: PMC9898926, DOI: 10.1186/s12958-023-01066-w.Peer-Reviewed Original ResearchConceptsAnti-Müllerian hormoneNumber of embryosEuploid embryosLive birthsOocyte qualityAge groupsSignificant independent predictorsCase-control analysisSART CORS databasePreimplantation genetic testingAMH levelsIVF cyclesIndependent predictorsIVF outcomesOocyte yieldNormal embryosPredictive roleGenetic testingFinal analysisBirthAgeIVFSubset of cyclesHormonePGT
2021
The Impact of Intracytoplasmic Sperm Injection in Non-Male Factor Infertility—A Critical Review
Glenn TL, Kotlyar AM, Seifer DB. The Impact of Intracytoplasmic Sperm Injection in Non-Male Factor Infertility—A Critical Review. Journal Of Clinical Medicine 2021, 10: 2616. PMID: 34198564, PMCID: PMC8231975, DOI: 10.3390/jcm10122616.Peer-Reviewed Original ResearchNon-male factor infertilityUse of ICSIIntracytoplasmic sperm injectionTotal fertilization failureFactor infertilityMale factor infertilityFertilization failureSperm injectionSafety of offspringLive birth rateFertilization rateICSI useSurveillance studyInfertilityBirth rateHigh rateInjectionNumerous studiesFailurePatientsIVF
2020
PREDICTING CUMULATIVE LIVE BIRTH BEFORE THE FIRST AND SECOND COMPLETE CYCLE OF IVF: A POPULATION-BASED STUDY OF LINKED CYCLE DATA FROM 79,512 WOMEN
McLernon D, Raja E, Baker V, Doody K, Lin P, Seifer D, Sparks A, Toner J, Wantman E, Bhattacharya S, Van Voorhis B. PREDICTING CUMULATIVE LIVE BIRTH BEFORE THE FIRST AND SECOND COMPLETE CYCLE OF IVF: A POPULATION-BASED STUDY OF LINKED CYCLE DATA FROM 79,512 WOMEN. Fertility And Sterility 2020, 114: e523-e524. DOI: 10.1016/j.fertnstert.2020.09.020.Peer-Reviewed Original Research
2014
Successful Same‐Cycle Blastocyst Transfer following Laparoscopic Ovarian Detorsion: A Report of Two Cases and Literature Review
Irani M, Tal R, Seifer DB, Grazi RV. Successful Same‐Cycle Blastocyst Transfer following Laparoscopic Ovarian Detorsion: A Report of Two Cases and Literature Review. Case Reports In Obstetrics And Gynecology 2014, 2014: 806378. PMID: 24864219, PMCID: PMC4020476, DOI: 10.1155/2014/806378.Peer-Reviewed Original ResearchOvarian torsionEmbryo transferOocyte retrievalFavorable pregnancy outcomeLaparoscopic ovarian detorsionOvarian detorsionLaparoscopic evaluationOvarian stimulationPregnancy outcomesFertilization cyclesInfertility patientsPregnancy chancesSuccessful pregnancyBlastocyst transferEgg retrievalClinical dilemmaOptimal timingDetorsionPatientsConcurrent cyclesSuch casesLiterature reviewPregnancyIVFCases
2002
Mitochondrial deletions in luteinized granulosa cells as a function of age in women undergoing in vitro fertilization
Seifer DB, DeJesus V, Hubbard K. Mitochondrial deletions in luteinized granulosa cells as a function of age in women undergoing in vitro fertilization. Fertility And Sterility 2002, 78: 1046-1048. PMID: 12413991, DOI: 10.1016/s0015-0282(02)04214-0.Peer-Reviewed Original ResearchConceptsGranulosa cellsAdvanced reproductive ageLuteinized granulosa cellsMitochondrial DNA deletionsGonadotropin stimulationReproductive ageMAIN OUTCOMEFollicular aspirationFertility clinicsFunction of ageYoung womenWomenIVFAgeDNA deletionsCellsMitochondrial deletionsYearsNormal mitochondriaNormal mtDNAPatientsDeletionClinicSubstantial decreaseDNA microarray analysis of the expression profiles of luteinized granulosa cells as a function of ovarian reserve
Chin KV, Seifer DB, Feng B, Lin Y, Shih WC. DNA microarray analysis of the expression profiles of luteinized granulosa cells as a function of ovarian reserve. Fertility And Sterility 2002, 77: 1214-1218. PMID: 12057731, DOI: 10.1016/s0015-0282(02)03114-x.Peer-Reviewed Original ResearchConceptsLuteinized granulosa cellsOvarian reserveDNA microarray analysisGranulosa cellsExpression profilesMicroarray analysisSequence tagsFertilization-embryo transferUniversity-based fertility clinicExpression profilingComplementary DNA microarray analysisGonadotropin stimulationFollicular aspirationMAIN OUTCOMEFertility clinicsWomenDNA microarraysGene expressionCellsGenesProfilingPatientsIVFClinicSignature patternsEarly follicular serum müllerian-inhibiting substance levels are associated with ovarian response during assisted reproductive technology cycles
Seifer DB, MacLaughlin DT, Christian BP, Feng B, Shelden RM. Early follicular serum müllerian-inhibiting substance levels are associated with ovarian response during assisted reproductive technology cycles. Fertility And Sterility 2002, 77: 468-471. PMID: 11872196, DOI: 10.1016/s0015-0282(01)03201-0.Peer-Reviewed Original ResearchConceptsOvarian responseMIS concentrationsReproductive technology cyclesGreater serum concentrationsGroup of womenOvulation inductionSerum concentrationsMaximum serumRetrospective analysisMAIN OUTCOMESubstance levelsSerum MISSerum samplesMI levelsWomenMature oocytesTechnology cyclesReproductive technologiesOocytesSerumART programsGroupIVFGreater number
1997
The impact of hydrosalpinx on successful pregnancy in tubal factor infertility treated by in vitro fertilization
Blazar A, Hogan J, Seifer D, Frishman G, Wheeler C, Haning R. The impact of hydrosalpinx on successful pregnancy in tubal factor infertility treated by in vitro fertilization. Fertility And Sterility 1997, 67: 517-520. PMID: 9091340, DOI: 10.1016/s0015-0282(97)80079-9.Peer-Reviewed Original ResearchConceptsTubal factor infertilityTubal diseaseFactor infertilityPregnancy rateCycle cancellation rateSuccess of IVFNumber of oocytesNumber of embryosHydrosalpinx groupRoutine salpingectomyOvarian stimulationOngoing pregnancyImplantation rateSuccessful pregnancyHydrosalpinxMAIN OUTCOMECancellation ratePatientsOocyte fertilizationInfertilityIVFIVF facilityPregnancyMore cyclesFertilization rate