2018
Vitamin D3 Regulates Follicular Development and Intrafollicular Vitamin D Biosynthesis and Signaling in the Primate Ovary
Xu J, Lawson MS, Xu F, Du Y, Tkachenko OY, Bishop CV, Pejovic-Nezhat L, Seifer DB, Hennebold JD. Vitamin D3 Regulates Follicular Development and Intrafollicular Vitamin D Biosynthesis and Signaling in the Primate Ovary. Frontiers In Physiology 2018, 09: 1600. PMID: 30487754, PMCID: PMC6246691, DOI: 10.3389/fphys.2018.01600.Peer-Reviewed Original ResearchVitamin D receptorVitamin D biosynthesisAntral folliclesVD3 supplementationFollicular developmentVitamin DAntral stagePrimate ovaryFollicle survivalVitamin D3D biosynthesisIsolated secondary folliclesOvarian follicle survivalOocyte maturationAnti-Müllerian hormone productionAdult rhesus macaquesParacrine factor productionStage-dependent mannerVD3 treatmentVDR expressionAMH productionDihydroxyvitamin D3Positive immunostainingD receptorProtein localization
2017
Potential therapeutic applications of human anti-Müllerian hormone (AMH) analogues in reproductive medicine
Kushnir VA, Seifer DB, Barad DH, Sen A, Gleicher N. Potential therapeutic applications of human anti-Müllerian hormone (AMH) analogues in reproductive medicine. Journal Of Assisted Reproduction And Genetics 2017, 34: 1105-1113. PMID: 28643088, PMCID: PMC5581791, DOI: 10.1007/s10815-017-0977-4.Peer-Reviewed Original ResearchConceptsAnti-Müllerian hormonePolycystic ovarian syndromePotential therapeutic applicationsReproductive medicineOnset of menopauseNew potential therapeutic applicationsOvarian follicular developmentTherapeutic applicationsSpecific disease conditionsPromising therapeutic applicationOvarian syndromeOvulation inductionFertility preservationPharmacologic agentsFollicular developmentHormone analogueReproductive tractDisease conditionsTherapeutic usesTGF-beta superfamilyAntagonist functionImportant regulatorDiagnostic purposesGonadal tissueKey regulator