2003
In vitro fertilization in the older patient.
Derman SG, Seifer DB. In vitro fertilization in the older patient. Current Women'S Health Reports 2003, 3: 375-83. PMID: 12959695.Peer-Reviewed Original ResearchConceptsOlder patientsClomiphene citrate challenge testBasal follicle-stimulating hormoneAntral follicle countDiminished ovarian reserveLower oocyte yieldFollicle-stimulating hormoneHigher miscarriage rateMüllerian-inhibiting substanceHigher cancellation rateIVF success ratesLower pregnancy ratesFlare protocolInhibin BIVF patientsMiscarriage rateOvarian reserveOvarian volumeFollicle countGnRH antagonistOocyte yieldEstradiol levelsPregnancy rateAgonist doseStimulation protocol
1998
Inhibin-B: The Physiologic Basis of the Clomiphene Citrate Challenge Test for Ovarian Reserve Screening 1This work was supported by The Bethesda Foundation.1
Hofmann G, Danforth D, Seifer D. Inhibin-B: The Physiologic Basis of the Clomiphene Citrate Challenge Test for Ovarian Reserve Screening 1This work was supported by The Bethesda Foundation.1. Fertility And Sterility 1998, 69: 474-477. PMID: 9531880, DOI: 10.1016/s0015-0282(97)00531-1.Peer-Reviewed Original ResearchConceptsClomiphene citrate challenge testInhibin B concentrationsNormal ovarian reserveDiminished ovarian reserveOvarian reserve screeningOvarian reserveDay 3Challenge testSerum inhibin B concentrationElevated FSH concentrationsTertiary fertility centerCycle day 3Cycle day 10Higher inhibin B concentrationsInhibin B productionFSH levelsFSH concentrationsFertility centerMAIN OUTCOMEPhysiologic basisFollicular apparatusDay 10WomenPatientsFertility evaluation