Featured Publications
Vaccination with BNT162b2 reduces transmission of SARS-CoV-2 to household contacts in Israel
Prunas O, Warren JL, Crawford FW, Gazit S, Patalon T, Weinberger DM, Pitzer VE. Vaccination with BNT162b2 reduces transmission of SARS-CoV-2 to household contacts in Israel. Science 2022, 375: eabl4292. PMID: 35084937, PMCID: PMC9261115, DOI: 10.1126/science.abl4292.Peer-Reviewed Original ResearchConceptsVaccine effectivenessSevere acute respiratory syndrome coronavirus 2Acute respiratory syndrome coronavirus 2Respiratory syndrome coronavirus 2Syndrome coronavirus 2Effectiveness of vaccinesEffectiveness of vaccinationTotal vaccine effectivenessSARS-CoV-2Household contactsSecond doseCoronavirus 2Household transmissionDelta variantDay 10VaccinationBNT162b2COVID-19InfectionChain binomial modelVaccineDoseImmunityAssociation Between the Decline in Pneumococcal Disease in Unimmunized Adults and Vaccine-Derived Protection Against Colonization in Toddlers and Preschool-Aged Children
Weinberger DM, Pitzer VE, Regev-Yochay G, Givon-Lavi N, Dagan R. Association Between the Decline in Pneumococcal Disease in Unimmunized Adults and Vaccine-Derived Protection Against Colonization in Toddlers and Preschool-Aged Children. American Journal Of Epidemiology 2018, 188: 160-168. PMID: 30462150, PMCID: PMC6321804, DOI: 10.1093/aje/kwy219.Peer-Reviewed Original ResearchConceptsInvasive pneumococcal diseaseUnimmunized adultsPneumococcal diseaseVaccine-associated immunityVaccine-derived protectionVaccine-targeted serotypesNationwide surveillance studyPrevalence of colonizationUnvaccinated adultsPneumococcal carriagePreschool aged childrenVaccine uptakeColonization prevalenceGroup of childrenVaccination coverageEmergency departmentSurveillance studyDisease ratesTrajectory of declineAge rangeAdultsAged childrenChildrenSerotypesVaccine
2022
Waning Effectiveness of the BNT162b2 Vaccine Against Infection in Adolescents in Israel
Prunas O, Weinberger D, Pitzer V, Gazit S, Patalon T. Waning Effectiveness of the BNT162b2 Vaccine Against Infection in Adolescents in Israel. Clinical Infectious Diseases 2022, 76: 113-118. PMID: 36484301, PMCID: PMC10202431, DOI: 10.1093/cid/ciac315.Peer-Reviewed Original ResearchConceptsMaccabi Healthcare ServicesBNT162b2 vaccineSecond doseAcute respiratory syndrome coronavirus 2 infectionSevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infectionSyndrome coronavirus 2 infectionPositive polymerase chain reaction testSARS-CoV-2 infectionPfizer BNT162b2 vaccineCoronavirus 2 infectionVaccine-induced immunityVaccine-induced protectionPolymerase chain reaction testIncidence of infectionCoronavirus disease 2019COVID-19Chain reaction testShort-term effectivenessCase-control designLong-term effectivenessVaccine effectivenessSymptomatic infectionLong-term protectionDisease 2019Delta variant
2021
Decline in Pneumococcal Disease in Young Children During the Coronavirus Disease 2019 (COVID-19) Pandemic in Israel Associated With Suppression of Seasonal Respiratory Viruses, Despite Persistent Pneumococcal Carriage: A Prospective Cohort Study
Danino D, Ben-Shimol S, Van Der Beek BA, Givon-Lavi N, Avni YS, Greenberg D, Weinberger DM, Dagan R. Decline in Pneumococcal Disease in Young Children During the Coronavirus Disease 2019 (COVID-19) Pandemic in Israel Associated With Suppression of Seasonal Respiratory Viruses, Despite Persistent Pneumococcal Carriage: A Prospective Cohort Study. Clinical Infectious Diseases 2021, 75: e1154-e1164. PMID: 34904635, PMCID: PMC8754767, DOI: 10.1093/cid/ciab1014.Peer-Reviewed Original ResearchConceptsCommunity-acquired alveolar pneumoniaInvasive pneumococcal diseasePneumococcal carriagePneumococcal diseaseRespiratory virusesSurveillance projectCOVID-19 pandemicBacteremic pneumococcal pneumoniaNasopharyngeal pneumococcal carriageSpecific respiratory virusesSARS-CoV-2 casesFirst SARS-CoV-2 caseLower respiratory infectionsProspective cohort studyPneumococcal carriage prevalencePneumococcal serotype distributionRespiratory syncytial virusSeasonal respiratory virusesRespiratory virus detectionChest X-rayDensity of colonizationAlveolar pneumoniaPneumococcal pneumoniaCohort studyRespiratory infections