2015
Novel Oral Anticoagulants: Efficacy, Laboratory Measurement, and Approaches to Emergent Reversal
Gehrie E, Tormey C. Novel Oral Anticoagulants: Efficacy, Laboratory Measurement, and Approaches to Emergent Reversal. Archives Of Pathology & Laboratory Medicine 2015, 139: 687-92. PMID: 25927153, DOI: 10.5858/arpa.2013-0677-rs.Peer-Reviewed Original ResearchConceptsNovel oral anticoagulantsManagement of NOACOral direct thrombin inhibitorDirect factor Xa inhibitorVitamin K antagonistsDirect thrombin inhibitorFactor Xa inhibitorsCertain clinical circumstancesOral anticoagulationWarfarin effectivenessK antagonistsOral anticoagulantsClinical efficacySafety profileEmergent reversalClinical circumstancesXa inhibitorsUS FoodDrug AdministrationThrombin inhibitorsNew drugsDrugsEfficacyInhibitorsLaboratory assays
2009
Platelet-Related Bleeding: An Update on Diagnostic Modalities and Therapeutic Options
Peddinghaus ME, Tormey CA. Platelet-Related Bleeding: An Update on Diagnostic Modalities and Therapeutic Options. Clinics In Laboratory Medicine 2009, 29: 175-191. PMID: 19665674, DOI: 10.1016/j.cll.2009.03.004.Peer-Reviewed Original ResearchConceptsPlatelet function testingFunction testingCare platelet function testingChronic clinical settingsPlatelet-related bleedingLife-threatening problemTransfusion strategyPlatelet dysfunctionTherapeutic optionsComponent therapyDiagnostic modalitiesClinical settingBleedingPatientsInitial studyLaboratory assaysTransfusionDysfunctionTherapyCare