2024
Next-generation digital chest tomosynthesis
Gange C, Ku J, Gosangi B, Liu J, Maolinbay M. Next-generation digital chest tomosynthesis. Journal Of Clinical Imaging Science 2024, 14: 22. PMID: 38975057, PMCID: PMC11225395, DOI: 10.25259/jcis_4_2024.Peer-Reviewed Original ResearchRadiation doseLow dose chest CTLung phantomLung nodulesEffective radiation dosePlane resolutionLow radiation doseLow dose CTPhantomSimulated pulmonary nodulesChest CTChest radiologistsHealthy volunteersPulmonary nodulesDose CTAnatomical locationNodule detectionImaging characteristicsTomosynthesisNodulesLungDoseDetect lung nodulesDevicesPotential utility
2023
Brief Report: Increasing Prevalence of Ground-Glass Nodules and Semisolid Lung Lesions on Outpatient Chest Computed Tomography Scans
Woodard G, Udelsman B, Prince S, Blasberg J, Dhanasopon A, Gange C, Traube L, Mase V, Boffa D, Detterbeck F, Bader A. Brief Report: Increasing Prevalence of Ground-Glass Nodules and Semisolid Lung Lesions on Outpatient Chest Computed Tomography Scans. JTO Clinical And Research Reports 2023, 4: 100583. PMID: 38074773, PMCID: PMC10709040, DOI: 10.1016/j.jtocrr.2023.100583.Peer-Reviewed Original ResearchGround-glass nodulesChest CT scanCT scanLung lesionsHealth systemLarge academic health systemAcademic health systemCross-sectional imagingRadiographic findingsPhysician consultationChest CTDatabase reviewTomography scanRadiographic lesionsAge groupsLesionsStudy periodLung nodulesOutpatient CTRadiology reportsAdult chestCTScansChestNodulesCardiothoracic complications of immune checkpoint inhibitors
Gosangi B, Wang Y, Rubinowitz A, Kwan J, Traube L, Gange C, Bader A. Cardiothoracic complications of immune checkpoint inhibitors. Clinical Imaging 2023, 102: 98-108. PMID: 37659356, DOI: 10.1016/j.clinimag.2023.08.001.Peer-Reviewed Educational MaterialsConceptsImmune checkpoint inhibitorsICI therapyCheckpoint inhibitorsOverall survivalTumor responseAdverse effectsDevelopment of irAEsNovel adverse effectsImproved overall survivalOverall patient outcomesICI administrationHematologic malignanciesPatient outcomesSolid tumorsIrAEsCancer treatmentGreater mortalityComplicationsTherapySurvivalInhibitorsMyocarditisPneumonitisPatientsMalignancy
2022
Diseases of the pulmonary arteries: imaging appearances and pearls
Cortopassi IO, Gosangi B, Asch D, Bader AS, Gange CP, Rubinowitz AN. Diseases of the pulmonary arteries: imaging appearances and pearls. Clinical Imaging 2022, 91: 111-125. PMID: 36067656, DOI: 10.1016/j.clinimag.2022.08.018.Peer-Reviewed Educational MaterialsConceptsContrast-enhanced chest CTChest X-rayPulmonary arteryEnlarged pulmonary arteryPulmonary vascular pathologyPulmonary artery anatomyEveryday clinical practiceAsymptomatic patientsImaging findingsPulmonary vasculatureArtery anatomyChest CTUrgent treatmentMediastinal structuresVascular pathologyArteryClinical practicePhysiologic dataEntire thoraxVessel wallPatientsDetailed evaluationPathologyWide spectrumQuantification of flowEarly-stage COVID-19 pandemic observations on pulmonary embolism using nationwide multi-institutional data harvesting
Wismüller A, DSouza AM, Abidin AZ, Ali Vosoughi M, Gange C, Cortopassi IO, Bozovic G, Bankier AA, Batra K, Chodakiewitz Y, Xi Y, Whitlow CT, Ponnatapura J, Wendt GJ, Weinberg EP, Stockmaster L, Shrier DA, Shin MC, Modi R, Lo HS, Kligerman S, Hamid A, Hahn LD, Garcia GM, Chung JH, Altes T, Abbara S, Bader AS. Early-stage COVID-19 pandemic observations on pulmonary embolism using nationwide multi-institutional data harvesting. Npj Digital Medicine 2022, 5: 120. PMID: 35986059, PMCID: PMC9388980, DOI: 10.1038/s41746-022-00653-2.Peer-Reviewed Original ResearchNatural language processingImage analysis serviceRadiology reportsSoftware infrastructureService requestsData harvestingAnalysis servicesLanguage processingCommercial AIGround truthManual reviewNLP accuracyExploratory toolResult dataComputed tomography pulmonary angiogramAIHealthcare systemPulmonary embolismInfrastructureRequestsEarly COVID-19 pandemicPE casesServicesAccuracyProcessingStandardizing the Reporting of Incidental, Non-Lung Cancer (Category S) Findings Identified on Lung Cancer Screening Low-Dose CT Imaging
Tanoue LT, Sather P, Cortopassi I, Dicks D, Curtis A, Michaud G, Bader A, Gange C, Detterbeck F, Killam J. Standardizing the Reporting of Incidental, Non-Lung Cancer (Category S) Findings Identified on Lung Cancer Screening Low-Dose CT Imaging. CHEST Journal 2022, 161: 1697-1706. PMID: 35032477, DOI: 10.1016/j.chest.2021.12.662.Peer-Reviewed Educational MaterialsConceptsLung cancer screeningCancer screeningIncidental findingAmerican CollegeLung cancer screening studyLung CT Screening ReportingRelevant specialty societiesLung nodulesCancer screening studyLow-dose CT scansPreventive health maintenanceStandardization of reportingLung cancerS findingsCancer findingsPatient distressLDCT scansCT scanPositive findingsHealth maintenanceCT imagingStandardized reportingSpecialty societiesScreening studyPotential harm
2021
COVID-19 ARDS: a review of imaging features and overview of mechanical ventilation and its complications
Gosangi B, Rubinowitz AN, Irugu D, Gange C, Bader A, Cortopassi I. COVID-19 ARDS: a review of imaging features and overview of mechanical ventilation and its complications. Emergency Radiology 2021, 29: 23-34. PMID: 34698956, PMCID: PMC8545770, DOI: 10.1007/s10140-021-01976-5.Peer-Reviewed Educational MaterialsConceptsAcute respiratory distress syndromeCOVID-19 acute respiratory distress syndromePulmonary interstitial emphysemaMechanical ventilationPathophysiology of ARDSVentilator-associated lung injuryCOVID-19Invasive mechanical ventilationRespiratory distress syndromeCOVID-19 pneumoniaHyaline membrane formationIntra-alveolar pressureMost COVID-19 casesImaging of patientsFeatures of complicationsAlveolar epithelial barrierBlood oxygen levelTension cystsLung injuryAlveolar ruptureDistress syndromeInterstitial emphysemaAlveolar edemaCOVID-19 casesInterstitial edema
2020
Social Distancing with Portable Chest Radiographs During the COVID-19 Pandemic: Assessment of Radiograph Technique and Image Quality Obtained at 6 Feet and Through Glass
Gange CP, Pahade JK, Cortopassi I, Bader AS, Bokhari J, Hoerner M, Thomas KM, Rubinowitz AN. Social Distancing with Portable Chest Radiographs During the COVID-19 Pandemic: Assessment of Radiograph Technique and Image Quality Obtained at 6 Feet and Through Glass. Radiology Cardiothoracic Imaging 2020, 2: e200420. PMID: 33778645, PMCID: PMC7673079, DOI: 10.1148/ryct.2020200420.Peer-Reviewed Original ResearchImaging in the Evaluation of Chest Pain in the Primary Care Setting, Part 1: Cardiovascular Etiologies
Bader AS, Rubinowitz AN, Gange CP, Bader EM, Cortopassi IO. Imaging in the Evaluation of Chest Pain in the Primary Care Setting, Part 1: Cardiovascular Etiologies. The American Journal Of Medicine 2020, 133: 1033-1038. PMID: 32442507, DOI: 10.1016/j.amjmed.2020.04.024.Peer-Reviewed Educational MaterialsConceptsChest painPrimary care settingCardiovascular etiologyCare settingsCommon presenting complaintPrimary care physiciansMultiple organ systemsPresenting complaintCare physiciansPainNumerous imaging modalitiesOrgan systemsImaging modalitiesEtiologyAppropriate testsCliniciansFindingsPhysiciansSettingComplaintsImaging in the Evaluation of Chest Pain in the Primary Care Setting, Part 2: Sources of Noncardiac Chest Pain
Bader AS, Rubinowitz AN, Gange CP, Bader EM, Cortopassi IO. Imaging in the Evaluation of Chest Pain in the Primary Care Setting, Part 2: Sources of Noncardiac Chest Pain. The American Journal Of Medicine 2020, 133: 1135-1142. PMID: 32442508, DOI: 10.1016/j.amjmed.2020.04.013.Peer-Reviewed Educational MaterialsMeSH KeywordsChest PainEsophageal Motility DisordersFractures, CompressionGastroesophageal RefluxHernia, HiatalHumansMagnetic Resonance ImagingMusculoskeletal DiseasesPleural EffusionPneumoniaPneumothoraxPrimary Health CareRadiography, ThoracicRespiratory Tract DiseasesRib FracturesSpinal FracturesThoracic WallTietze's SyndromeTomography, X-Ray ComputedConceptsChest painPrimary care settingCare settingsNoncardiac chest painCommon presenting complaintPrimary care physiciansMultiple organ systemsNoncardiac sourcesPresenting complaintCare physiciansMusculoskeletal etiologyRadiologic appearancePainNumerous imaging modalitiesOrgan systemsImaging modalitiesAppropriate testsEtiologyCliniciansFindingsPhysiciansSettingComplaintsRadiologic-Pathologic Correlation for Nondiagnostic CT-Guided Lung Biopsies Performed for the Evaluation of Lung Cancer.
Ma Y, Byrne SC, Gange C, Hunsaker AR, Hammer MM. Radiologic-Pathologic Correlation for Nondiagnostic CT-Guided Lung Biopsies Performed for the Evaluation of Lung Cancer. American Journal Of Roentgenology 2020, 215: 116-120. PMID: 32160056, DOI: 10.2214/ajr.19.22244.Peer-Reviewed Original ResearchConceptsLung biopsyPathology resultsThoracic radiologistsRepeat biopsyAtypical cellsHerder modelCT-guided lung biopsyRadiologic-pathologic concordanceNormal lung tissuesCases of inflammationLung malignancyRetrospective studyFinal diagnosisLung cancerLung tissuePathologic correlationBiopsyMalignancyROC curvePneumoniaPatientsLower ratesHigh rateRadiologistsScores
2018
Incremental Value of Magnetic Resonance Imaging in Further Characterizing Hypodense Mediastinal and Paracardiac Lesions Identified on Computed Tomography.
Chaturvedi A, Gange C, Sahin H, Chaturvedi A. Incremental Value of Magnetic Resonance Imaging in Further Characterizing Hypodense Mediastinal and Paracardiac Lesions Identified on Computed Tomography. Journal Of Clinical Imaging Science 2018, 8: 10. PMID: 29619281, PMCID: PMC5868235, DOI: 10.4103/jcis.JCIS_63_17.Peer-Reviewed Original Research
2017
Traumatic Rib Injury: Patterns, Imaging Pitfalls, Complications, and Treatment—Erratum
Talbot BS, Gange CP, Chaturvedi A, Klionsky N, Hobbs SK, Chaturvedi A. Traumatic Rib Injury: Patterns, Imaging Pitfalls, Complications, and Treatment—Erratum. RadioGraphics 2017, 37: 1004-1004. PMID: 28493796, DOI: 10.1148/rg.2017174003.Peer-Reviewed Original ResearchTraumatic Rib Injury: Patterns, Imaging Pitfalls, Complications, and Treatment
Talbot BS, Gange CP, Chaturvedi A, Klionsky N, Hobbs SK, Chaturvedi A. Traumatic Rib Injury: Patterns, Imaging Pitfalls, Complications, and Treatment. RadioGraphics 2017, 37: 160100. PMID: 28186860, DOI: 10.1148/rg.2017160100.Peer-Reviewed Original ResearchConceptsRib injuriesRib fracturesAbdominal solid organ injuriesPediatric nonaccidental traumaPrimary osseous neoplasmsSolid organ injuryAcute vascular injuryCare of patientsEmergency department settingOrgan-specific injuryPrinciples of managementPulmonary contusionFlail chestMetastatic diseasePathologic fracturePulmonary lacerationThoracic traumaTrauma complicationsPaget's diseaseSignificant morbidityNonaccidental traumaVascular injuryBifid ribsDepartment settingExtrapleural hematoma
2006
Targeted cDNA differential display (TcDD).
Nguyen GH, Nguyen NC, Storm N, Gange C, Gavras H, Smith CL. Targeted cDNA differential display (TcDD). Biomolecular Engineering 2006, 23: 41-54. PMID: 16466965, DOI: 10.1016/j.bioeng.2005.12.001.Peer-Reviewed Original Research