2022
Cerebral Volumetric Correlates of Apathy in Alzheimer’s Disease and Cognitively Normal Older Adults: Meta-Analysis, Label-Based Review, and Study of an Independent Cohort
Chaudhary S, Zhornitsky S, Chao HH, van Dyck CH, Li CR. Cerebral Volumetric Correlates of Apathy in Alzheimer’s Disease and Cognitively Normal Older Adults: Meta-Analysis, Label-Based Review, and Study of an Independent Cohort. Journal Of Alzheimer's Disease 2022, 85: 1251-1265. PMID: 34924392, PMCID: PMC9215906, DOI: 10.3233/jad-215316.Peer-Reviewed Original ResearchConceptsAlzheimer's diseaseInferior frontal gyrusIndependent cohortEmotional scoresHealthy controlsCognitive impairmentVolumetric correlatesMini-Mental State Examination scoreAD/mild cognitive impairmentNeuroanatomical correlatesState Examination scoreApathy Evaluation ScaleGray matter volumeVoxel-based morphometryRight inferior frontal gyrusLabel-based reviewMild cognitive impairmentNormal older adultsCortical atrophyHigh morbidityBasal gangliaRight putamenMatter volumeAnterior cingulateReduced quality
2020
Altered multimodal magnetic resonance parameters of basal nucleus of Meynert in Alzheimer’s disease
Zheng W, Li H, Cui B, Liang P, Wu Y, Han X, Li C, Li K, Wang Z. Altered multimodal magnetic resonance parameters of basal nucleus of Meynert in Alzheimer’s disease. Annals Of Clinical And Translational Neurology 2020, 7: 1919-1929. PMID: 32888399, PMCID: PMC7545587, DOI: 10.1002/acn3.51176.Peer-Reviewed Original ResearchConceptsGray matter volumeHealthy controlsFunctional connectivityBasal nucleusResting-state functional connectivityDaily living statusLower gray matter volumeArterial spin labeling imagingWhole-brain functional connectivityRegional blood flowPostmortem human brainVoxel-based morphometryCholinergic dysfunctionHigher rCBFRight insula