2022
Win and Loss Responses in the Monetary Incentive Delay Task Mediate the Link between Depression and Problem Drinking
Chen Y, Dhingra I, Le T, Zhornitsky S, Zhang S, Li C. Win and Loss Responses in the Monetary Incentive Delay Task Mediate the Link between Depression and Problem Drinking. Brain Sciences 2022, 12: 1689. PMID: 36552149, PMCID: PMC9775947, DOI: 10.3390/brainsci12121689.Peer-Reviewed Original ResearchSuperior temporal gyrusMonetary incentive delay taskAlcohol Use Disorders Identification TestParahippocampal gyrusAlcohol misuseNeural correlatesReward processingWhole-brain regressionAltered reward processingIncentive delay taskDepression InventoryBDI-II scoresRight parahippocampal gyrusAlcohol use disorderDelay taskDisorders Identification TestLoss processingTemporal gyrusFrontoparietal regionsNeural markersBeck Depression InventoryDrinking adultsMediation analysisProblem drinkingSeverity of drinking
2021
Noradrenergic correlates of chronic cocaine craving: neuromelanin and functional brain imaging
Wang W, Zhornitsky S, Zhang S, Li CR. Noradrenergic correlates of chronic cocaine craving: neuromelanin and functional brain imaging. Neuropsychopharmacology 2021, 46: 851-859. PMID: 33408330, PMCID: PMC8027452, DOI: 10.1038/s41386-020-00937-9.Peer-Reviewed Original Research
2019
The effects of age on reward magnitude processing in the monetary incentive delay task
Dhingra I, Zhang S, Zhornitsky S, Le T, Wang W, Chao HH, Levy I, Li CR. The effects of age on reward magnitude processing in the monetary incentive delay task. NeuroImage 2019, 207: 116368. PMID: 31743790, PMCID: PMC7463276, DOI: 10.1016/j.neuroimage.2019.116368.Peer-Reviewed Original ResearchConceptsMonetary incentive delay taskIncentive delay taskSupplementary motor areaMagnitude of rewardAge-related differencesDelay taskRT differencesRegional activationAge effectsEffect of ageReaction time differencesRight anterior insulaMiddle frontal gyrusReward-directed behaviorExplicit cuesMagnitude processingBrain activationRight caudate headAnterior insulaFrontal gyrusReward magnitudeLarge rewardPrimary motor cortexCerebral processesParahippocampal gyrus
2018
Ventral striatal dysfunction in cocaine dependence – difference mapping for subregional resting state functional connectivity
Zhang S, Li CR. Ventral striatal dysfunction in cocaine dependence – difference mapping for subregional resting state functional connectivity. Translational Psychiatry 2018, 8: 119. PMID: 29915214, PMCID: PMC6006289, DOI: 10.1038/s41398-018-0164-0.Peer-Reviewed Original ResearchConceptsState functional connectivityCocaine dependenceVentral striatumFunctional connectivityVentral striatal dysfunctionExtent of depressionCircuit deficitsDopaminergic deficitFunctional dysconnectivityStriatal dysfunctionRSFC differencesVmPFC connectivitySubregional changesRsFC changesParahippocampal gyrusCocaine cravingCortical connectivityHealthy populationVentromedial prefrontal cortexVisual cortexMental illnessCocaine useRSFCPrefrontal cortexFunctional subregions
2017
The Effects of Age, from Young to Middle Adulthood, and Gender on Resting State Functional Connectivity of the Dopaminergic Midbrain
Peterson AC, Zhang S, Hu S, Chao HH, Li CR. The Effects of Age, from Young to Middle Adulthood, and Gender on Resting State Functional Connectivity of the Dopaminergic Midbrain. Frontiers In Human Neuroscience 2017, 11: 52. PMID: 28223929, PMCID: PMC5293810, DOI: 10.3389/fnhum.2017.00052.Peer-Reviewed Original ResearchSubstantia nigra pars compactaVentral tegmental areaAttention-deficit/ hyperactivity disorderState functional connectivityAge-related changesEffect of ageFunctional connectivityParahippocampal gyrusParkinson's diseaseMiddle adulthoodDopaminergic ventral tegmental areaBilateral angular gyrusOrbital frontal regionsBlood oxygenation level-dependent (BOLD) signalLevel-dependent signalPosterior orbital gyrusTime courseNeural basisDopaminergic midbrainHyperactivity disorderNeural mechanismsAngular gyrusPars compactaFrontal regionsDopaminergic structures
2016
The effects of methylphenidate on cerebral responses to conflict anticipation and unsigned prediction error in a stop-signal task
Manza P, Hu S, Ide JS, Farr OM, Zhang S, Leung HC, Li CR. The effects of methylphenidate on cerebral responses to conflict anticipation and unsigned prediction error in a stop-signal task. Journal Of Psychopharmacology 2016, 30: 283-293. PMID: 26755547, PMCID: PMC4837899, DOI: 10.1177/0269881115625102.Peer-Reviewed Original ResearchConceptsUnsigned prediction errorsStop-signal taskConflict anticipationVentromedial prefrontal cortexEffects of methylphenidateDorsal anterior cingulateInferior parietal lobulePresupplementary motor areaCognitive controlHealthy young adultsNeural processesUpcoming conflictTask performanceNeural mechanismsBilateral caudate headParietal lobulePrediction errorPrefrontal cortexAnterior cingulateAdaptive behaviorParahippocampal gyrusMethylphenidateMotor areaAnticipation activityYoung adults
2015
Individual variation in the neural processes of motor decisions in the stop signal task: the influence of novelty seeking and harm avoidance personality traits
Hu J, Lee D, Hu S, Zhang S, Chao H, Li CS. Individual variation in the neural processes of motor decisions in the stop signal task: the influence of novelty seeking and harm avoidance personality traits. Brain Structure And Function 2015, 221: 2607-2618. PMID: 25989852, PMCID: PMC4654717, DOI: 10.1007/s00429-015-1061-4.Peer-Reviewed Original ResearchConceptsStop-signal taskHarm avoidanceNeural processesSignal taskPersonality traitsStudy of cognitionWhole-brain regressionRegional brain activationRisk-taking processesCognitive controlExecutive controlStop errorBrain activationFMRI studyBehavioral tasksMotor decisionsFrontopolar cortexMonetary rewardsNovelty seekingRisk-taking responsesBilateral orbitofrontalExplicit manipulationDorsomedial prefrontalRegional activationParahippocampal gyrus