2024
The Neural Correlates of Individual Differences in Reinforcement Learning during Pain Avoidance and Reward Seeking
Le T, Oba T, Couch L, McInerney L, Li C. The Neural Correlates of Individual Differences in Reinforcement Learning during Pain Avoidance and Reward Seeking. ENeuro 2024, 11: eneuro.0437-23.2024. PMID: 38365840, PMCID: PMC10901196, DOI: 10.1523/eneuro.0437-23.2024.Peer-Reviewed Original ResearchConceptsSuperior frontal gyrusReward-seekingCingulate cortexNeural correlatesPain avoidanceAction biasDorsal anterior cingulate cortexLeft posterior cingulate cortexAction-outcome associationsGo/No-Go taskAnterior cingulate cortexPosterior cingulate cortexImpact of outcomesHigher learning rateReward trialsFrontal gyrusAvoidance learningMidcingulate cortexNeural substratesAssociative learningAction tendenciesPre-SMAAssociated with activationPrecentral gyrusPostcentral gyrus
2021
Midcingulate Cortical Activations Interrelate Chronic Craving and Physiological Responses to Negative Emotions in Cocaine Addiction
Zhornitsky S, Le TM, Wang W, Dhingra I, Chen Y, Li CR, Zhang S. Midcingulate Cortical Activations Interrelate Chronic Craving and Physiological Responses to Negative Emotions in Cocaine Addiction. Biological Psychiatry Global Open Science 2021, 1: 37-47. PMID: 35664438, PMCID: PMC9164547, DOI: 10.1016/j.bpsgos.2021.03.003.Peer-Reviewed Original ResearchCD subjectsCocaine cravingMidcingulate cortexControl subjectsSkin conductance responsesBrain activationHealthy control subjectsCocaine Craving QuestionnaireCocaine-dependent subjectsInferior parietal gyrusRegional brain activationChronic cocaineParietal gyrusMotor circuitsPhysiological responsesCocaine addictionDrug cravingCravingNeutral images