2016
Novelty Seeking, Harm Avoidance, and Cerebral Responses to Conflict Anticipation: An Exploratory Study
Hu J, Hu S, Maisano JR, Chao HH, Zhang S, Li CR. Novelty Seeking, Harm Avoidance, and Cerebral Responses to Conflict Anticipation: An Exploratory Study. Frontiers In Human Neuroscience 2016, 10: 546. PMID: 27857686, PMCID: PMC5093128, DOI: 10.3389/fnhum.2016.00546.Peer-Reviewed Original ResearchInferior parietal lobuleConflict anticipationProactive controlLateral orbitofrontal cortexMiddle frontal gyrusHarm avoidancePre-supplementary motor areaBilateral inferior parietal lobuleRight inferior parietal lobuleCognitive control circuitsWhole-brain linear regressionTrial reaction timeStop-signal taskRegional brain activationRight lateral orbitofrontal cortexCerebral responsesIndividual differencesSignal taskBrain activationFMRI studyTridimensional Personality QuestionnaireFrontal gyrusGreater activationHA traitExploratory study
2014
Dissociable Roles of Right Inferior Frontal Cortex and Anterior Insula in Inhibitory Control: Evidence from Intrinsic and Task-Related Functional Parcellation, Connectivity, and Response Profile Analyses across Multiple Datasets
Cai W, Ryali S, Chen T, Li CS, Menon V. Dissociable Roles of Right Inferior Frontal Cortex and Anterior Insula in Inhibitory Control: Evidence from Intrinsic and Task-Related Functional Parcellation, Connectivity, and Response Profile Analyses across Multiple Datasets. Journal Of Neuroscience 2014, 34: 14652-14667. PMID: 25355218, PMCID: PMC4212065, DOI: 10.1523/jneurosci.3048-14.2014.Peer-Reviewed Original ResearchConceptsRight inferior frontal cortexRight anterior insulaTask-evoked functional connectivityInferior frontal cortexFrontal cortexInhibitory controlFunctional connectivityAnterior insulaFronto-parietal cortexIntrinsic brain activityAnterior cingulate cortexResponse profilesDissociable rolesCortex volumeIndependent cohortControl studyCingulate cortexDorsomedial prefrontalCortexDistinct functional characteristicsGreater activationResponse profile analysisBrain activityDifferential rolesInsula
2012
Saliency Processing and Obesity: A Preliminary Imaging Study of the Stop Signal Task
Hendrick OM, Luo X, Zhang S, Li C. Saliency Processing and Obesity: A Preliminary Imaging Study of the Stop Signal Task. Obesity 2012, 20: 1796-1802. PMID: 21720427, PMCID: PMC3653271, DOI: 10.1038/oby.2011.180.Peer-Reviewed Original ResearchConceptsStop-signal taskObese femalesBrain activationCognitive controlAltered cerebral functionSupplementary motor areaSignal taskRegional brain activationInferior parietal cortexSaliency processingCerebral functionLean femalesMotor areaFunctional magnetic resonance imagesParietal cortexSimilar behavioral performanceImaging studiesStop trialsPreliminary imaging studyObesityMagnetic resonance imagesTrialsGreater activationResonance imagesResponse inhibitionThe influence of risky and conservative mental sets on cerebral activations of cognitive control
Winkler AD, Hu S, Li CS. The influence of risky and conservative mental sets on cerebral activations of cognitive control. International Journal Of Psychophysiology 2012, 87: 254-261. PMID: 22922525, PMCID: PMC3511622, DOI: 10.1016/j.ijpsycho.2012.08.010.Peer-Reviewed Original ResearchConceptsStop-signal taskMental setCognitive controlSignal taskCerebral activationPre-supplementary motor areaGo reaction timePrevious imaging workReaction timeReward uncertaintyCognitive functioningIndividual differencesStop errorGreater activationNeural responsesSalient eventsContextual effectsImaging workRetrosplenial cortexMore salientAdult participantsMotor areaSuccess trialsCerebral responsesReward
2010
A cerebellar thalamic cortical circuit for error-related cognitive control
Ide JS, Li CS. A cerebellar thalamic cortical circuit for error-related cognitive control. NeuroImage 2010, 54: 455-464. PMID: 20656038, PMCID: PMC2962720, DOI: 10.1016/j.neuroimage.2010.07.042.Peer-Reviewed Original ResearchConceptsPost-error slowingAnterior cingulate cortexVentrolateral prefrontal cortexVLPFC activationGranger causality mappingSupplementary motor areaCognitive controlExecutive functionBehavioral adjustmentError-related cognitive controlDorsal anterior cingulate cortexPost-error processingError-related activityBrain regionsCortical circuitsVLPFC activityPrefrontal activitySignal taskError detectionGreater activationPrefrontal cortexCingulate cortexSubcortical activationThalamic-cortical circuitMotor area
2009
A neural measure of behavioral engagement: Task-residual low-frequency blood oxygenation level-dependent activity in the precuneus
Zhang S, Li CS. A neural measure of behavioral engagement: Task-residual low-frequency blood oxygenation level-dependent activity in the precuneus. NeuroImage 2009, 49: 1911-1918. PMID: 19761851, PMCID: PMC2791356, DOI: 10.1016/j.neuroimage.2009.09.004.Peer-Reviewed Original ResearchConceptsBlood oxygenation level-dependent activityRegional brain activationLevel-dependent activityTask engagementNeural measuresNeural processesBrain activationPosterior cingulate cortexAttentional monitoringResponse inhibitionHuman cognitionPrefrontal activationSignal taskGreater activationBOLD activityBehavioral engagementCingulate cortexPrecuneusBrain regionsLow-frequency fluctuationsFractional amplitudeBrain imagingSeed regionIndependent component analysisEngagementGender Differences in Cognitive Control: an Extended Investigation of the Stop Signal Task
Li CS, Zhang S, Duann JR, Yan P, Sinha R, Mazure CM. Gender Differences in Cognitive Control: an Extended Investigation of the Stop Signal Task. Brain Imaging And Behavior 2009, 3: 262-276. PMID: 19701485, PMCID: PMC2728908, DOI: 10.1007/s11682-009-9068-1.Peer-Reviewed Original ResearchRegional brain activationTrial reaction timeStop-signal taskCognitive controlBrain activationGo-trial reaction timesRight inferior parietal lobuleGender differencesReaction timeSub-cortical areasInferior parietal lobuleFunctional magnetic resonancePost-SEClinical conditionsControl disordersCortical activationClinical implicationsParietal lobuleInitiate studiesResponse inhibitionNeural processesSignal taskGreater activationWomenMen
2008
Subcortical processes of motor response inhibition during a stop signal task
Li CS, Yan P, Sinha R, Lee TW. Subcortical processes of motor response inhibition during a stop signal task. NeuroImage 2008, 41: 1352-1363. PMID: 18485743, PMCID: PMC2474693, DOI: 10.1016/j.neuroimage.2008.04.023.Peer-Reviewed Original ResearchConceptsMotor response inhibitionSubthalamic nucleusStop-signal reaction timeStop-signal taskResponse inhibitionShorter stop-signal reaction timesSignal inhibitionMagnetic resonance imaging studyGreater activationLonger stop-signal reaction timesSignal taskResonance imaging studyFunctional magnetic resonance imaging studySubcortical processesStop-signal inhibitionGroups of subjectsSubthalamic activityBasal gangliaSignal reaction timeThalamic nucleiCaudate headImaging studiesStop trialsMedial prefrontal activityCortical mechanisms
2007
Greater activation of the “default” brain regions predicts stop signal errors
Li CS, Yan P, Bergquist KL, Sinha R. Greater activation of the “default” brain regions predicts stop signal errors. NeuroImage 2007, 38: 640-648. PMID: 17884586, PMCID: PMC2097963, DOI: 10.1016/j.neuroimage.2007.07.021.Peer-Reviewed Original ResearchConceptsSignal taskBehavioral adjustmentBrain regionsPost-error behavioral adjustmentCingulate cortexMidline brain regionsStop-signal taskPerigenual anterior cingulate cortexSignal detection theoryPosterior cingulate cortexAnterior cingulate cortexCortical brain regionsCognitive tasksStop successElicit errorsError processingNeural processesStop errorFMRI studyMental effortGreater activationPerformance errorsDetection theoryBilateral precuneusTask
2006
Gender differences in the neural correlates of response inhibition during a stop signal task
Li CS, Huang C, Constable RT, Sinha R. Gender differences in the neural correlates of response inhibition during a stop signal task. NeuroImage 2006, 32: 1918-1929. PMID: 16806976, DOI: 10.1016/j.neuroimage.2006.05.017.Peer-Reviewed Original ResearchConceptsStop-signal taskBrain activationResponse inhibitionGreater activationSignal taskAnterior cingulate cortexRegional brain activationNeural correlatesCognitive-motor tasksGender differencesFunctional magnetic resonanceStop-signal inhibitionMotor thalamusGlobus pallidusSubcortical areasYears of educationMotor circuitryCingulate cortexBrain regionsCaudate tailMotor tasksWomenSuccess rateLower statistical thresholdMenImaging Response Inhibition in a Stop-Signal Task: Neural Correlates Independent of Signal Monitoring and Post-Response Processing
Li CS, Huang C, Constable RT, Sinha R. Imaging Response Inhibition in a Stop-Signal Task: Neural Correlates Independent of Signal Monitoring and Post-Response Processing. Journal Of Neuroscience 2006, 26: 186-192. PMID: 16399686, PMCID: PMC6674298, DOI: 10.1523/jneurosci.3741-05.2006.Peer-Reviewed Original ResearchConceptsStop-signal reaction timeStop-signal taskResponse inhibitionPre-potent response tendenciesReaction timeShorter stop-signal reaction timesEfficient response inhibitionFunctional magnetic resonanceLonger stop-signal reaction timesGroups of subjectsHigher cortical functionsError monitoringNeural correlatesTask demandsHabitual responsesBrain activationNeural substrataResponse tendenciesGreater activationInhibitory controlAffective functionsMotor areaBrain regionsFrontal cortexCortical function
2005
Neuroimaging study of sex differences in the neuropathology of cocaine abuse
Li CS, Kemp K, Milivojevic V, Sinha R. Neuroimaging study of sex differences in the neuropathology of cocaine abuse. Gender Medicine 2005, 2: 174-182. PMID: 16290890, DOI: 10.1016/s1550-8579(05)80046-4.Peer-Reviewed Original ResearchConceptsRegional brain activationBrain activationGreater activationBrain regionsSex differencesScript-guided imagerySubstance abusersCerebral perfusion deficitsBlood oxygenation level-dependent (BOLD) signalSame statistical thresholdCocaine-dependent menCue-induced cravingSuperior frontal gyrusLevel-dependent signalChronic cocaine useMale substance abusersSex-related factorsCocaine use disorderImportant sex differencesLeft uncusStress trialsClinical outcomesPerfusion deficitsRight claustrumPharmacologic challenge