2023
Sleep dysfunction mediates the relationship between hypothalamic-insula connectivity and anxiety-depression symptom severity bidirectionally in young adults
Li G, Chen Y, Chaudhary S, Li C, Hao D, Yang L, Li C. Sleep dysfunction mediates the relationship between hypothalamic-insula connectivity and anxiety-depression symptom severity bidirectionally in young adults. NeuroImage 2023, 279: 120340. PMID: 37611815, DOI: 10.1016/j.neuroimage.2023.120340.Peer-Reviewed Original ResearchConceptsPittsburgh Sleep Quality IndexRight insulaSymptom severityMediation analysisSleep dysfunctionWhole-brain regressionHuman Connectome Project datasetSubjective mood stateYoung adultsState functional connectivityDepression symptom severityNegative emotionsCognitive performanceEmotional deficitsEmotional statesPotential sex differencesAffective functionsDrinking severityMood statesMotivated behaviorFunctional connectivityPoor sleep qualityRSFCSleep Quality IndexSleep quality
2018
The Comorbidity Between Internet Gaming Disorder and Depression: Interrelationship and Neural Mechanisms
Liu L, Yao YW, Li CR, Zhang JT, Xia CC, Lan J, Ma SS, Zhou N, Fang XY. The Comorbidity Between Internet Gaming Disorder and Depression: Interrelationship and Neural Mechanisms. Frontiers In Psychiatry 2018, 9: 154. PMID: 29740358, PMCID: PMC5924965, DOI: 10.3389/fpsyt.2018.00154.Peer-Reviewed Original ResearchInternet gaming disorderDorsolateral prefrontal cortexNeural mechanismsLeft amygdalaGaming disorderRight dorsolateral prefrontal cortexDepression symptomsPrecentral gyrusAutoregressive cross-lagged modelingBrain imaging researchExecutive control networkResting-state functional connectivity studyCross-lagged modelingFunctional connectivity studiesLongitudinal survey studyNeural levelBrain mechanismsEmotional deficitsPrefrontal cortexCognitive deficitsPsychotherapy interventionsControl participantsIGD severityCollege studentsConnectivity studies