2023
Joint motion estimation and penalized image reconstruction algorithm with anatomical priors for gated TOF-PET/CT
Tsai Y, Liu C. Joint motion estimation and penalized image reconstruction algorithm with anatomical priors for gated TOF-PET/CT. Physics In Medicine And Biology 2023, 68: 025020. PMID: 36549009, DOI: 10.1088/1361-6560/acae19.Peer-Reviewed Original Research
2019
Direct List Mode Parametric Reconstruction for Dynamic Cardiac SPECT
Shi L, Lu Y, Wu J, Gallezot JD, Boutagy N, Thorn S, Sinusas AJ, Carson RE, Liu C. Direct List Mode Parametric Reconstruction for Dynamic Cardiac SPECT. IEEE Transactions On Medical Imaging 2019, 39: 119-128. PMID: 31180845, PMCID: PMC7030971, DOI: 10.1109/tmi.2019.2921969.Peer-Reviewed Original ResearchConceptsAppropriate kinetic modelConventional indirect methodImage reconstruction algorithmKinetic modelHigh noise levelsLow count levelsVivo canine studyIndirect methodImage noiseNoise levelParametric reconstructionNoiseReconstruction algorithmFrame imagePatient radiation dose reductionMethodDirect methodLower image noise
2018
Respiratory Motion Compensation for PET/CT with Motion Information Derived from Matched Attenuation-Corrected Gated PET Data
Lu Y, Fontaine K, Mulnix T, Onofrey JA, Ren S, Panin V, Jones J, Casey ME, Barnett R, Kench P, Fulton R, Carson RE, Liu C. Respiratory Motion Compensation for PET/CT with Motion Information Derived from Matched Attenuation-Corrected Gated PET Data. Journal Of Nuclear Medicine 2018, 59: 1480-1486. PMID: 29439015, PMCID: PMC6126443, DOI: 10.2967/jnumed.117.203000.Peer-Reviewed Original ResearchConceptsMotion correction frameworkMotion informationReference gatePET reconstructionMotion estimation accuracyGated PET dataMotion compensation approachMotion correctionMotion compensation methodMotion estimationRespiratory motion compensationAttenuation correction artifactsLung cancer datasetMotion compensationCT imagesNAC approachReconstruction algorithmPET dataPET imagesNew frameworkInaccurate localizationCancer datasetsBreathing variationsAttenuation correction mapsHuman datasets
2017
Investigation of Sub-Centimeter Lung Nodule Quantification for Low-Dose PET
Lu Y, Fontaine K, Germino M, Mulnix T, Casey M, Carson R, Liu C. Investigation of Sub-Centimeter Lung Nodule Quantification for Low-Dose PET. IEEE Transactions On Radiation And Plasma Medical Sciences 2017, 2: 41-50. DOI: 10.1109/trpms.2017.2778008.Peer-Reviewed Original ResearchMotion amplitudeLarge motion amplitudesVoxel sizeRespiratory motion correctionComprehensive simulationsReconstruction voxel sizeSimulationsMotion correctionPhantom studyFlight positron emission tomographyResolution recovery reconstructionMore accurate quantificationReconstruction algorithmAccurate quantificationHigh-resolution timeDifferent upsampling methodsUpsampling methodPositron emission tomographyAmplitudeSizeAdditional reductionNon-Rigid Event-by-Event Continuous Respiratory Motion Compensated List-Mode Reconstruction for PET
Chan C, Onofrey J, Jian Y, Germino M, Papademetris X, Carson RE, Liu C. Non-Rigid Event-by-Event Continuous Respiratory Motion Compensated List-Mode Reconstruction for PET. IEEE Transactions On Medical Imaging 2017, 37: 504-515. PMID: 29028189, PMCID: PMC7304524, DOI: 10.1109/tmi.2017.2761756.Peer-Reviewed Original ResearchConceptsMotion-compensated image reconstructionMotion fieldImage reconstructionReconstruction algorithmRespiratory motionNon-rigid motionNon-rigid motion correctionSignificant image blurringSystem matrixMotion correctionSystem matrix calculationMotionImage blurringSuperior image qualityTracer concentrationRigid motionReference locationMatrix calculationList-mode reconstruction algorithmMotion correlationDynamics studyImage quality