2012
Linking DNA Methyltransferases to Epigenetic Marks and Nucleosome Structure Genome-wide in Human Tumor Cells
Jin B, Ernst J, Tiedemann R, Xu H, Sureshchandra S, Kellis M, Dalton S, Liu C, Choi J, Robertson K. Linking DNA Methyltransferases to Epigenetic Marks and Nucleosome Structure Genome-wide in Human Tumor Cells. Cell Reports 2012, 2: 1411-1424. PMID: 23177624, PMCID: PMC3625945, DOI: 10.1016/j.celrep.2012.10.017.Peer-Reviewed Original ResearchMeSH KeywordsCarcinoma, EmbryonalCell LineChromatinCpG IslandsDNADNA (Cytosine-5-)-Methyltransferase 1DNA (Cytosine-5-)-MethyltransferasesDNA MethylationDNA Methyltransferase 3AEmbryonic Stem CellsEpigenomicsGenes, OverlappingGenetic LociGenome, HumanHCT116 CellsHistonesHumansMaleNucleosomesProtein BindingTesticular NeoplasmsTranscription, GeneticConceptsDNA methylationDNA methyltransferasesDifferentiated stateGenome-wide localizationCancerous stem cellsEpigenetic marksMammalian developmentHistone modificationsNucleosome structureCellular transformationDNA hypermethylationLocalization patternsHuman tumor cellsMethylationDNMTsHuman tumor cell linesTumor cell linesStem cellsMethyltransferasesCancer cellsCell linesLociCellsTumor cellsEpigenome
2011
Expression of an IRF-3 fusion protein and mouse estrogen receptor, inhibits hepatitis C viral replication in RIG-I-deficient Huh 7.5 cells
Yao L, Yan X, Dong H, Nelson D, Liu C, Li X. Expression of an IRF-3 fusion protein and mouse estrogen receptor, inhibits hepatitis C viral replication in RIG-I-deficient Huh 7.5 cells. Virology Journal 2011, 8: 445. PMID: 21936899, PMCID: PMC3213043, DOI: 10.1186/1743-422x-8-445.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsCell LineDEAD Box Protein 58DEAD-box RNA HelicasesGene ExpressionHepacivirusHepatocytesHumansInterferon Regulatory Factor-3Interferon-alphaInterferon-betaMiceProtein BiosynthesisProtein MultimerizationReal-Time Polymerase Chain ReactionReceptors, EstrogenReceptors, ImmunologicRecombinant Fusion ProteinsTranscription, GeneticVirus ReplicationConceptsAnti-HCV effectInterferon regulatory factor 3Huh-7.5 cellsEstrogen receptorPolymerase chain reactionHepatitis C virus infectionViral replicationC virus infectionMouse estrogen receptorHepatitis C viral replicationInterferon-stimulated gene expressionExpression of IFNHCV viral replicationHCV RNA replicationReal-time polymerase chain reactionEstrogen receptor agonistsExpression of ISGsRegulatory factor 3HCV IRES-dependent translation