2024
Lisdexamfetamine maintenance treatment for binge-eating disorder following successful treatments: randomized double-blind placebo-controlled trial
Grilo C, Ivezaj V, Yurkow S, Tek C, Wiedemann A, Gueorguieva R. Lisdexamfetamine maintenance treatment for binge-eating disorder following successful treatments: randomized double-blind placebo-controlled trial. Psychological Medicine 2024, 54: 3334-3344. PMID: 39258475, PMCID: PMC11496227, DOI: 10.1017/s003329172400148x.Peer-Reviewed Original ResearchEating-disorder psychopathologyBinge-eating disorderMaintenance treatmentAcute treatmentBinge-eating remission ratesCognitive-behavioral therapyEfficacy of lisdexamfetamineSignificant weight gainDouble-blind placebo-controlled trialAcute respondersLisdexamfetamine treatmentPsychopathological outcomesPosttreatment assessmentLisdexamfetaminePlacebo-controlled trialRandomized double-blind placebo-controlled trialSingle-site trialAssociated with significant weight lossPsychopathologyBinge-eatingRemission rateWeight lossPlaceboRelapse rateControl researchOvervaluation of shape/weight at posttreatment predicts relapse at 12‐month follow‐up after successful behaviorally‐based treatment of binge‐eating disorder
Grilo C, Ivezaj V, Gueorguieva R. Overvaluation of shape/weight at posttreatment predicts relapse at 12‐month follow‐up after successful behaviorally‐based treatment of binge‐eating disorder. International Journal Of Eating Disorders 2024, 57: 1268-1273. PMID: 38321617, PMCID: PMC11093697, DOI: 10.1002/eat.24141.Peer-Reviewed Original ResearchOvervaluation of shape/weightEating-disorder psychopathologyBinge-eating disorderEating Disorder Examination interviewBeck Depression InventoryWeight loss treatmentClinical overvaluationBinge-eating frequencyDiagnostic specifierBinge eatingNon-abstinenceExamination interviewDepression InventoryShape/weightDepression scoresFollow-upPsychopathologyAbstinenceBingeDepressionClinical implicationsDepression 1PosttreatmentDisordersOvervaluationReliability of the original and brief versions of the Eating Disorder Examination in binge‐eating disorder
Lydecker J, Ivezaj V, Wiedemann A, Kerrigan S, Grilo C. Reliability of the original and brief versions of the Eating Disorder Examination in binge‐eating disorder. Obesity 2024, 32: 702-709. PMID: 38311600, PMCID: PMC10965370, DOI: 10.1002/oby.23993.Peer-Reviewed Original ResearchEating Disorder ExaminationEating Disorder Examination interviewEating-disorder psychopathologyBinge-eating disorderInternal consistencyDoctoral-levelIndicators of loss of controlInterrater reliabilityLoss of controlBinge eatingBinge-eating episodesPsychological treatmentPsychometric propertiesPsychometric studyTests of reliabilityBehavioral indicatorsAssessed adultsClinical researchPsychopathologyEatingRatersDisordersAudio-recordedAdultsPatient groupThe children of parents who receive treatment for binge‐eating disorder experience improvements in disordered eating
Lydecker J, Ozbardakci E, Grilo C. The children of parents who receive treatment for binge‐eating disorder experience improvements in disordered eating. International Journal Of Eating Disorders 2024, 57: 745-751. PMID: 38308384, PMCID: PMC10947894, DOI: 10.1002/eat.24153.Peer-Reviewed Original ResearchBinge-eating disorderBinge eatingDisordered eating behaviorsEating behaviorsSecretive eatingParent changesDisordered eatingAssociated with disordered eating behaviorsEating-disorder psychopathologyEnd-of-treatment assessmentParental eating disordersAssociated with changesChildren of parentsCross-sectional workChild disordered eating behaviorsBinge-eating frequencyEating disordersSchool-aged childrenParental treatmentUntreated family membersParent medicationLongitudinal researchBingeBaseline assessmentEating
2023
Shape discrepancy, weight bias internalization, and eating-disorder psychopathology in patients with loss-of-control eating after bariatric surgery
Dunford A, Ivezaj V, Grilo C. Shape discrepancy, weight bias internalization, and eating-disorder psychopathology in patients with loss-of-control eating after bariatric surgery. Surgery For Obesity And Related Diseases 2023, 20: 291-296. PMID: 37926627, PMCID: PMC10922050, DOI: 10.1016/j.soard.2023.09.028.Peer-Reviewed Original ResearchBariatric surgeryEating Disorder Examination-Bariatric Surgery Version interviewControl eatingCurrent body mass indexWeight lossPoor weight lossBody mass indexED psychopathologyEating-disorder psychopathologyMental health outcomesPostoperative interventionsPostoperative lossEating Disorder PsychopathologyMass indexPercent weight lossResults Most participantsWeight bias internalizationSurgeryYale University SchoolHealth outcomesPatientsSomatic concernsWeight concernsMost participantsMethods ParticipantsRacial differences after bariatric surgery: 24-month follow-up of a randomized, controlled trial for postoperative loss-of-control eating
Ivezaj V, Dilip A, Duffy A, Grilo C. Racial differences after bariatric surgery: 24-month follow-up of a randomized, controlled trial for postoperative loss-of-control eating. Surgery For Obesity And Related Diseases 2023, 20: 261-266. PMID: 37949690, PMCID: PMC10922356, DOI: 10.1016/j.soard.2023.09.017.Peer-Reviewed Original ResearchEating-disorder psychopathologyPercent excess weight lossExcess weight lossPost-bariatric surgeryNon-white patientsWhite patientsEating Disorder Examination-Bariatric Surgery Version interviewGreater percent excess weight lossGreater eating-disorder psychopathologyMonths post-bariatric surgeryWeight lossBDI-II depression scoreLong-term outcomesPost-operative lossRacial differencesAcademic medical centerBeck Depression InventoryBariatric surgeryShort-term findingsControlled TrialsProspective studyMedical CenterDepression scoresBetter outcomesPatientsBinge-Eating Disorder Interventions: Review, Current Status, and Implications
Grilo C, Juarascio A. Binge-Eating Disorder Interventions: Review, Current Status, and Implications. Current Obesity Reports 2023, 12: 406-416. PMID: 37439970, PMCID: PMC10528223, DOI: 10.1007/s13679-023-00517-0.Peer-Reviewed Original ResearchConceptsPsychological treatmentSpecific psychological treatmentsEating-disorder psychopathologyEvidence-based treatmentsAdditional pharmacological optionsDisorder interventionsSerious psychiatric problemsBehavioral lifestyle interventionScalable interventionsEffective interventionsFuture researchCBTPsychiatric problemsBingeMixed outcomesInterventionCBTgshModest weight lossRecent findingsResearchPsychopathologyShameLifestyle interventionPharmacological optionsSubstantial morbidityPredictors of early weight loss in post‐bariatric surgery patients receiving adjunctive behavioural treatments for loss‐of‐control eating
Smith C, Dilip A, Ivezaj V, Duffy A, Grilo C. Predictors of early weight loss in post‐bariatric surgery patients receiving adjunctive behavioural treatments for loss‐of‐control eating. Clinical Obesity 2023, 13: e12603. PMID: 37257889, PMCID: PMC10524670, DOI: 10.1111/cob.12603.Peer-Reviewed Original ResearchConceptsEarly weight lossAdjunctive behavioral treatmentsPost-bariatric surgery patientsEarly weight changeBaseline patient characteristicsSurgery-related variablesMonths of treatmentWeight lossBehavioral treatmentPatient characteristicsSurgery patientsFirst monthWeight changeTime of surgeryWeight gain groupEating-disorder psychopathologyBariatric surgeryMost patientsAdjunctive treatmentBlack patientsPercent weight lossPsychiatric comorbidityClinical variablesTreatment trialsPatientsLoss of control in binge‐eating disorder: Fear and resignation
Perelman H, Gilbert K, Grilo C, Lydecker J. Loss of control in binge‐eating disorder: Fear and resignation. International Journal Of Eating Disorders 2023, 56: 1199-1206. PMID: 36920120, PMCID: PMC10247475, DOI: 10.1002/eat.23929.Peer-Reviewed Original ResearchConceptsBinge-eating disorderCognitive-affective experiencesLoss of controlModerate treatment outcomeBinge-eating episodesEating-disorder psychopathologyTreatment-seeking patientsFuture researchAbsence of fearGreater distressPsychopathologyFearSevere psychopathologyResearch cliniciansSemistructured interviewsTreatment formulationPast monthDisordersResignationTreatment outcomesExperienceBlack individualsEmotionsTreatment planningIndividualsPsychiatric comorbidity as a prospective predictor of long-term weight and psychosocial outcomes after bariatric surgery
Ivezaj V, Dilip A, Grilo C. Psychiatric comorbidity as a prospective predictor of long-term weight and psychosocial outcomes after bariatric surgery. General Hospital Psychiatry 2023, 83: 51-58. PMID: 37099869, DOI: 10.1016/j.genhosppsych.2023.03.005.Peer-Reviewed Original ResearchConceptsEating Disorder Examination-Bariatric Surgery VersionLong-term weight outcomesPost-bariatric surgeryPsychiatric comorbidityEating-disorder psychopathologyBariatric surgeryWeight outcomesMonths post-bariatric surgeryMini International Neuropsychiatric InterviewWeight loss outcomesCurrent psychiatric disorderCurrent psychiatric comorbidityInternational Neuropsychiatric InterviewPsychosocial functioning outcomesLong-term weightBeck Depression InventoryPoor psychosocial functioningPrognostic significanceProspective studyBariatric populationNeuropsychiatric InterviewClinical significanceComorbiditiesLoss outcomesPsychiatric disorders
2020
Physical activity and psychosocial correlates following bariatric surgery among patients with loss-of-control eating
Lawson J, Kerrigan S, Carr M, Wiedemann A, Ivezaj V, Grilo C. Physical activity and psychosocial correlates following bariatric surgery among patients with loss-of-control eating. Mental Health And Physical Activity 2020, 19: 100343. DOI: 10.1016/j.mhpa.2020.100343.Peer-Reviewed Original ResearchBody mass indexBariatric surgeryPhysical activityPhysical functioningEating Disorder Examination-Bariatric Surgery Version interviewSR-PAPercent total weight lossSelf-reported physical activityLevel of PAGreater Physical ActivityBariatric surgery outcomesHealth-related qualityPsychosocial correlatesModerate physical activityBetter physical functioningObjective physical activityEating-disorder psychopathologyBetter psychosocial functioningGastrectomy surgeryMedical managementMass indexPhysical functionSurgery outcomesInactive lifestyleSurgery
2018
Food addiction among men and women in India
Wiedemann AA, Lawson JL, Cunningham PM, Khalvati KM, Lydecker JA, Ivezaj V, Grilo CM. Food addiction among men and women in India. European Eating Disorders Review 2018, 26: 597-604. PMID: 30003654, PMCID: PMC6261447, DOI: 10.1002/erv.2613.Peer-Reviewed Original ResearchConceptsHealth-related qualityBody mass indexHigher severity scoresEating-disorder psychopathologyClinical featuresMass indexSF-12Severity scoreClinical thresholdFood addictionEDE-Q subscalesYFAS scoresHigher depressionGreater frequencyYFASScoresNonclinical groupSelf-report measuresWomenDepressionMenFood addiction among Spanish-speaking Latino/as residing in the United States
Ivezaj V, Wiedemann AA, Lydecker JA, Grilo CM. Food addiction among Spanish-speaking Latino/as residing in the United States. Eating Behaviors 2018, 30: 61-65. PMID: 29870970, PMCID: PMC6047914, DOI: 10.1016/j.eatbeh.2018.05.009.Peer-Reviewed Original ResearchConceptsBody mass indexYale Food Addiction ScaleFood addictionDepressive symptomsPoorer overall mental healthClinical levelYFAS scoresHigher YFAS scoresEating-disorder psychopathologyAnonymous web-based surveyFood addiction symptomsOverall mental healthMass indexMean ageSF-12PHQ-2Physical functioningWeb-based surveyClinical thresholdParticipant groupsAssociated psychopathologyMental healthSimilar findingsSymptomsWeight/shapeComparing men and women with binge‐eating disorder and co‐morbid obesity
Lydecker JA, Grilo CM. Comparing men and women with binge‐eating disorder and co‐morbid obesity. International Journal Of Eating Disorders 2018, 51: 411-417. PMID: 29493793, PMCID: PMC5980708, DOI: 10.1002/eat.22847.Peer-Reviewed Original ResearchConceptsBody mass indexBinge-eating disorderEating-disorder psychopathologyBinge-eating episodesBinge-eating behaviorClinical presentationResearch cliniciansHigher body mass indexCo-morbid obesityDSM-IV disordersStructured Clinical InterviewEating Disorder Examination interviewAge of onsetBinge-eating frequencyRace/ethnicityMass indexBED diagnosisClinical InterviewYounger ageObesityExamination interviewWomenMenAgeDisorders
2017
Driven exercise in the absence of binge eating: Implications for purging disorder
Lydecker JA, Shea M, Grilo CM. Driven exercise in the absence of binge eating: Implications for purging disorder. International Journal Of Eating Disorders 2017, 51: 139-145. PMID: 29215743, PMCID: PMC5796839, DOI: 10.1002/eat.22811.Peer-Reviewed Original ResearchConceptsEating-disorder psychopathologyClinical significancePhysical activityCompensatory behaviorsBinge-eating episodesAbsence of bingeEating Disorder PsychopathologyLower depression levelsLow-frequency thresholdsWeb-based surveyDepression levelsSmall sample sizeHigher depressionOverall frequencyLaxativesTreatment researchMost domainsExerciseBingePsychopathologyDisordersDepressionParticipantsSimilar levelsFurther supportForm and Formulation: Examining the Distinctiveness of Body Image Constructs in Treatment-Seeking Patients With Binge-Eating Disorder
Lydecker JA, White MA, Grilo CM. Form and Formulation: Examining the Distinctiveness of Body Image Constructs in Treatment-Seeking Patients With Binge-Eating Disorder. Journal Of Consulting And Clinical Psychology 2017, 85: 1095-1103. PMID: 29083224, PMCID: PMC5679782, DOI: 10.1037/ccp0000258.Peer-Reviewed Original ResearchConceptsBody image variablesBody image disturbanceBody image constructsBinge-eating disorderImage constructImage variablesWeight/shape overvaluationBinge-eating frequencyInvestigator-based interviewBiopsychosocial featuresEating-disorder psychopathologyTreatment-seeking patientsShape preoccupationShape dissatisfactionShape overvaluationShape concernsCore aspectsCurrent studyTreatment formulationConstructsImportant distinctionDifferent aspectsOvervaluationPreoccupationDisordersDoes your child's weight influence how you judge yourself as a parent? A cross-sectional study to define and examine parental overvaluation of weight/shape
Lydecker JA, Grilo CM. Does your child's weight influence how you judge yourself as a parent? A cross-sectional study to define and examine parental overvaluation of weight/shape. Preventive Medicine 2017, 105: 265-270. PMID: 28987340, PMCID: PMC5659758, DOI: 10.1016/j.ypmed.2017.10.009.Peer-Reviewed Original ResearchConceptsWeight/shapeParental overvaluationPersonal weightEating-disorder psychopathologyBinge-eating disorderEating PsychopathologyParent psychopathologyPediatric obesityDearth of researchChild weightCross-sectional designParental attitudesPsychopathologyImportant psychopathologyDisorder treatmentCross-sectional studyParentsCurrent studyIntegral stakeholdersWeight influenceOvervaluationClinical attentionChild BMIChild healthRelated conceptsEvaluation of the DSM‐5 Severity Indicator for Anorexia Nervosa
Machado PP, Grilo CM, Crosby RD. Evaluation of the DSM‐5 Severity Indicator for Anorexia Nervosa. European Eating Disorders Review 2017, 25: 221-223. PMID: 28402070, PMCID: PMC8674740, DOI: 10.1002/erv.2508.Peer-Reviewed Original ResearchRumination in Patients with Binge‐Eating Disorder and Obesity: Associations with Eating‐Disorder Psychopathology and Weight‐bias Internalization
Wang SB, Lydecker JA, Grilo CM. Rumination in Patients with Binge‐Eating Disorder and Obesity: Associations with Eating‐Disorder Psychopathology and Weight‐bias Internalization. European Eating Disorders Review 2017, 25: 98-103. PMID: 28078784, PMCID: PMC5318238, DOI: 10.1002/erv.2499.Peer-Reviewed Original ResearchConceptsShape/weightWeight bias internalizationEating-disorder psychopathologyBinge-eating disorderCognitive processesGreater eating-disorder psychopathologyImportant cognitive processesOvervaluation of shapeGreater weight bias internalizationHierarchical multiple regressionTreatment-seeking patientsGreater ruminationRuminationDiscrimination experiencesPhysical healthPsychopathologyNegative attitudesMultiple regressionOvervaluationObesity treatmentComorbid obesityAttitudesDisordersExperienceFindings
2016
Children of parents with BED have more eating behavior disturbance than children of parents with obesity or healthy weight
Lydecker JA, Grilo CM. Children of parents with BED have more eating behavior disturbance than children of parents with obesity or healthy weight. International Journal Of Eating Disorders 2016, 50: 648-656. PMID: 27859458, PMCID: PMC5429220, DOI: 10.1002/eat.22648.Peer-Reviewed Original ResearchConceptsBinge-eating disorderChild weightChildren's bingeEating-disorder psychopathologyHigher child weightCross-sectional findingsChild overweightProspective confirmationChildren's eatingChild feedingChild overeatingDietary restrictionObesityClinical interventionsPrevention effortsEating Disorder BehaviorsDisordersBingePreliminary evidencePotential factorsEatingCurrent studyLimited literatureCore featuresOB