2024
Exploring Dietary Restraint as a Mediator of Behavioral and Cognitive‐Behavioral Treatments on Outcomes for Patients With Binge‐Eating Disorder With Obesity
Grilo C, Pittman B. Exploring Dietary Restraint as a Mediator of Behavioral and Cognitive‐Behavioral Treatments on Outcomes for Patients With Binge‐Eating Disorder With Obesity. International Journal Of Eating Disorders 2024 PMID: 39247962, DOI: 10.1002/eat.24288.Peer-Reviewed Original ResearchCognitive-behavioral therapyBehavioral weight lossBinge-eating disorderBinge eatingWeight loss outcomesCognitive-behavioral treatmentMediation of behaviorEDE-Q restraintPost-treatmentCognitive-behavioralRestraint ScaleDietary restraintBingeMediation effectEatingEffects of treatmentTreatment effectsDisordersRandomized controlled trialsWeight lossMonths of treatmentHypothesis-testingSecondary analysisRestraintBinge-eatingOvervaluation of shape/weight at posttreatment predicts relapse at 12‐month follow‐up after successful behaviorally‐based treatment of binge‐eating disorder
Grilo C, Ivezaj V, Gueorguieva R. Overvaluation of shape/weight at posttreatment predicts relapse at 12‐month follow‐up after successful behaviorally‐based treatment of binge‐eating disorder. International Journal Of Eating Disorders 2024, 57: 1268-1273. PMID: 38321617, PMCID: PMC11093697, DOI: 10.1002/eat.24141.Peer-Reviewed Original ResearchOvervaluation of shape/weightEating-disorder psychopathologyBinge-eating disorderEating Disorder Examination interviewBeck Depression InventoryWeight loss treatmentClinical overvaluationBinge-eating frequencyDiagnostic specifierBinge eatingNon-abstinenceExamination interviewDepression InventoryShape/weightDepression scoresFollow-upPsychopathologyAbstinenceBingeDepressionClinical implicationsDepression 1PosttreatmentDisordersOvervaluationThe children of parents who receive treatment for binge‐eating disorder experience improvements in disordered eating
Lydecker J, Ozbardakci E, Grilo C. The children of parents who receive treatment for binge‐eating disorder experience improvements in disordered eating. International Journal Of Eating Disorders 2024, 57: 745-751. PMID: 38308384, PMCID: PMC10947894, DOI: 10.1002/eat.24153.Peer-Reviewed Original ResearchBinge-eating disorderBinge eatingDisordered eating behaviorsEating behaviorsSecretive eatingParent changesDisordered eatingAssociated with disordered eating behaviorsEating-disorder psychopathologyEnd-of-treatment assessmentParental eating disordersAssociated with changesChildren of parentsCross-sectional workChild disordered eating behaviorsBinge-eating frequencyEating disordersSchool-aged childrenParental treatmentUntreated family membersParent medicationLongitudinal researchBingeBaseline assessmentEating
2023
Binge-Eating Disorder Interventions: Review, Current Status, and Implications
Grilo C, Juarascio A. Binge-Eating Disorder Interventions: Review, Current Status, and Implications. Current Obesity Reports 2023, 12: 406-416. PMID: 37439970, PMCID: PMC10528223, DOI: 10.1007/s13679-023-00517-0.Peer-Reviewed Original ResearchConceptsPsychological treatmentSpecific psychological treatmentsEating-disorder psychopathologyEvidence-based treatmentsAdditional pharmacological optionsDisorder interventionsSerious psychiatric problemsBehavioral lifestyle interventionScalable interventionsEffective interventionsFuture researchCBTPsychiatric problemsBingeMixed outcomesInterventionCBTgshModest weight lossRecent findingsResearchPsychopathologyShameLifestyle interventionPharmacological optionsSubstantial morbidityPredictors and significance of rapid response to behaviorally based treatment of binge eating disorder
Yurkow S, Ivezaj V, Grilo C. Predictors and significance of rapid response to behaviorally based treatment of binge eating disorder. Obesity 2023, 31: 390-398. PMID: 36623872, PMCID: PMC9877118, DOI: 10.1002/oby.23648.Peer-Reviewed Original ResearchConceptsDemographic featuresTreatment attitudesWeight lossFourth treatment weekWeight loss outcomesPsychiatric variablesSuperior clinical outcomesWeight loss treatmentTreatment of bingeClinical severity variablesClinical outcomesPrognostic significanceTreatment weekClinical trialsBaseline predictorsLoss outcomesLoss treatmentPosttreatment outcomesBinge eatingIndependent assessorsBingeSeverity variablesDisordersPatientsTreatment
2017
Driven exercise in the absence of binge eating: Implications for purging disorder
Lydecker JA, Shea M, Grilo CM. Driven exercise in the absence of binge eating: Implications for purging disorder. International Journal Of Eating Disorders 2017, 51: 139-145. PMID: 29215743, PMCID: PMC5796839, DOI: 10.1002/eat.22811.Peer-Reviewed Original ResearchConceptsEating-disorder psychopathologyClinical significancePhysical activityCompensatory behaviorsBinge-eating episodesAbsence of bingeEating Disorder PsychopathologyLower depression levelsLow-frequency thresholdsWeb-based surveyDepression levelsSmall sample sizeHigher depressionOverall frequencyLaxativesTreatment researchMost domainsExerciseBingePsychopathologyDisordersDepressionParticipantsSimilar levelsFurther supportCorrelates of weight-related quality of life among individuals with binge eating disorder before and after cognitive behavioral therapy
Mason TB, Crosby RD, Kolotkin RL, Grilo CM, Mitchell JE, Wonderlich SA, Crow SJ, Peterson CB. Correlates of weight-related quality of life among individuals with binge eating disorder before and after cognitive behavioral therapy. Eating Behaviors 2017, 27: 1-6. PMID: 28843136, PMCID: PMC5700842, DOI: 10.1016/j.eatbeh.2017.08.001.Peer-Reviewed Original ResearchConceptsCognitive behavioral therapyED psychopathologyBody mass indexWeight-related qualityBehavioral therapyEnd of treatmentSelf-report measuresPhysical functionSubjective bingeDisorder psychopathologyPublic distressPsychosocial variablesLongitudinal associationsPsychosocial factorsPsychopathologyNumber of EDsCopingBingeCurrent studyMass indexAvailable treatmentsDistressPredictor variablesFollowing associationsWeight loss
2016
Children of parents with BED have more eating behavior disturbance than children of parents with obesity or healthy weight
Lydecker JA, Grilo CM. Children of parents with BED have more eating behavior disturbance than children of parents with obesity or healthy weight. International Journal Of Eating Disorders 2016, 50: 648-656. PMID: 27859458, PMCID: PMC5429220, DOI: 10.1002/eat.22648.Peer-Reviewed Original ResearchConceptsBinge-eating disorderChild weightChildren's bingeEating-disorder psychopathologyHigher child weightCross-sectional findingsChild overweightProspective confirmationChildren's eatingChild feedingChild overeatingDietary restrictionObesityClinical interventionsPrevention effortsEating Disorder BehaviorsDisordersBingePreliminary evidencePotential factorsEatingCurrent studyLimited literatureCore featuresOBBinge abstinence is associated with reduced energy intake after treatment in patients with binge eating disorder and obesity
Masheb RM, Dorflinger LM, Rolls BJ, Mitchell DC, Grilo CM. Binge abstinence is associated with reduced energy intake after treatment in patients with binge eating disorder and obesity. Obesity 2016, 24: 2491-2496. PMID: 27797154, PMCID: PMC5172456, DOI: 10.1002/oby.21664.Peer-Reviewed Original ResearchConceptsCognitive behavioral therapyPsychological functioningBinge abstinencePsychological outcomesCombination of CBTBehavioral therapyBingeRecall interviewsFunctioningAbstinence ratesDietary recall interviewsReduced energy intakeAbstinenceSignificant reductionWeight statusPsychiatric morbidityGreater improvementAdult patientsDietary counselingFruit intakeSugar intakeEnergy intakeDisordersAbstinentComplete cessationPreferred descriptions for loss of control while eating and weight among patients with binge eating disorder
Roberto CA, Galbraith K, Lydecker JA, Ivezaj V, Barnes RD, White MA, Grilo CM. Preferred descriptions for loss of control while eating and weight among patients with binge eating disorder. Psychiatry Research 2016, 246: 548-553. PMID: 27821368, PMCID: PMC5161684, DOI: 10.1016/j.psychres.2016.09.045.Peer-Reviewed Original ResearchCombining Pharmacological and Psychological Treatments for Binge Eating Disorder: Current Status, Limitations, and Future Directions
Grilo CM, Reas DL, Mitchell JE. Combining Pharmacological and Psychological Treatments for Binge Eating Disorder: Current Status, Limitations, and Future Directions. Current Psychiatry Reports 2016, 18: 55. PMID: 27086316, DOI: 10.1007/s11920-016-0696-z.Peer-Reviewed Original ResearchConceptsCognitive behavioral therapyBinge Eating DisorderFuture treatment researchPsychological treatmentBehavioral therapyRecurrent bingeEating DisordersCompensatory behaviorsTreatment researchPharmacological treatmentHeightened levelsBehavioral weight loss interventionFuture researchWeight loss interventionLimited researchCurrent clinical practiceBingeCertain medicationsLoss interventionFuture directionsBWLClinical practiceWeight controlDisordersSuperior outcomesFood Thought Suppression Inventory: Test–retest reliability and relationship to weight loss treatment outcomes
Barnes RD, Ivezaj V, Grilo CM. Food Thought Suppression Inventory: Test–retest reliability and relationship to weight loss treatment outcomes. Eating Behaviors 2016, 22: 93-95. PMID: 27112114, PMCID: PMC5161461, DOI: 10.1016/j.eatbeh.2016.04.001.Peer-Reviewed Original ResearchConceptsFood Thought Suppression InventoryWeight loss treatmentBinge-eating episodesTest-retest reliabilityLoss treatmentWeight loss treatment outcomesWeight lossWeight loss goalsOriginal body weightWeek test-retest reliabilityPercent weight lossPrimary careTreatment outcomesIntra-class correlationBody weightBaselineTreatmentScoresEpisodesParticipantsPost assessmentHigh levelsBingeRandomized controlled trial testing behavioral weight loss versus multi-modal stepped-care treatment for binge eating disorder
Grilo C. Randomized controlled trial testing behavioral weight loss versus multi-modal stepped-care treatment for binge eating disorder. European Psychiatry 2016, 33: s163. DOI: 10.1016/j.eurpsy.2016.01.321.Peer-Reviewed Original ResearchStepped-care treatmentAnti-obesity medicationsRemission rateWeight lossBehavioral weight lossCo-morbid obesityStepped-care modelObese BED patientsSignificant time effectInitial respondersTreatment challengesBED patientsMedicationsMixed model analysisPatientsBingePlaceboMonthsObesityBWLTreatmentStructured interviewsCBTDisordersMixed modelsShared and unique mechanisms underlying binge eating disorder and addictive disorders
Schulte EM, Grilo CM, Gearhardt AN. Shared and unique mechanisms underlying binge eating disorder and addictive disorders. Clinical Psychology Review 2016, 44: 125-139. PMID: 26879210, PMCID: PMC5796407, DOI: 10.1016/j.cpr.2016.02.001.Peer-Reviewed Original Research
2015
Examining the mediating roles of binge eating and emotional eating in the relationships between stress and metabolic abnormalities
Chao A, Grey M, Whittemore R, Reuning-Scherer J, Grilo CM, Sinha R. Examining the mediating roles of binge eating and emotional eating in the relationships between stress and metabolic abnormalities. Journal Of Behavioral Medicine 2015, 39: 320-332. PMID: 26686376, PMCID: PMC5576015, DOI: 10.1007/s10865-015-9699-1.Peer-Reviewed Original ResearchConceptsEmotional eatingBinge eatingModerators of genderSelf-reported stressPsychological mechanismsMorning cortisolEatingNegative relationshipMorning blood drawPhysiological assessmentHomeostatic modelGenderBingeModeratorRelationshipWaist circumferenceMetabolic abnormalitiesInsulin resistanceSupportParticipantsCortisolMediationMediatesAdultsCross-sectional studySmoking status and psychosocial factors in binge eating disorder and bulimia nervosa
Chao AM, White MA, Grilo CM. Smoking status and psychosocial factors in binge eating disorder and bulimia nervosa. Eating Behaviors 2015, 21: 54-58. PMID: 26741260, PMCID: PMC4851572, DOI: 10.1016/j.eatbeh.2015.12.011.Peer-Reviewed Original ResearchConceptsEating-disorder psychopathologyDepressive symptomsBulimia nervosaBeck Depression InventoryCurrent smokersSmoking historyEating Disorder Examination QuestionnaireSmoking statusCigarette smokingDisorder Examination QuestionnairePsychosocial factorsAdult volunteersDepression InventorySymptomsBattery of questionnairesDisorder psychopathologyBN groupNon-clinical groupCommunity volunteersExamination QuestionnaireSmokersSignificant differencesBingeNervosaVolunteersNeurobiological features of binge eating disorder
Balodis IM, Grilo CM, Potenza MN. Neurobiological features of binge eating disorder. CNS Spectrums 2015, 20: 557-565. PMID: 26530404, PMCID: PMC4658223, DOI: 10.1017/s1092852915000814.Peer-Reviewed Original ResearchConceptsBinge-eating disorderOrbitofrontal cortexTreatment of BEDPalatable food cuesInhibitory control processesFrontostriatal areasMotivational processesFood cuesCue responsesPrefrontal areasNeurobiological featuresNeural featuresControl processTreatment effortsSpecific relationshipNeural functionDisordersBingeCuesSystematic reviewRewardHypofunctioningCortexMeasuresFindingsPsychosocial and metabolic function by smoking status in individuals with binge eating disorder and obesity
Udo T, White MA, Barnes RD, Ivezaj V, Morgan P, Masheb RM, Grilo CM. Psychosocial and metabolic function by smoking status in individuals with binge eating disorder and obesity. Addictive Behaviors 2015, 53: 46-52. PMID: 26451703, PMCID: PMC4679522, DOI: 10.1016/j.addbeh.2015.09.018.Peer-Reviewed Original ResearchConceptsTreatment-seeking adultsTreatment-seeking patientsSubstance use disordersDisorder psychopathologyCurrent smokersFormer smokersPsychosocial functioningComorbid psychiatric disordersSmoking statusLifetime psychiatric comorbidityUse disordersLifetime diagnostic criteriaPotential long-term implicationsFunctioningBingePsychiatric comorbidityMeeting criteriaPsychiatric disordersMetabolic functionsMetabolic functioningMetabolic riskMetabolic syndromeMetabolic abnormalitiesSmoking cessationSmokersFamily histories of anxiety in overweight men and women with binge eating disorder: A preliminary investigation
Blomquist KK, Grilo CM. Family histories of anxiety in overweight men and women with binge eating disorder: A preliminary investigation. Comprehensive Psychiatry 2015, 62: 161-169. PMID: 26343481, PMCID: PMC4583821, DOI: 10.1016/j.comppsych.2015.07.007.Peer-Reviewed Original ResearchConceptsPsychological functioningAnxiety disordersDisorder psychopathologyBED patientsDevelopment of bingeDSM-IV anxiety disordersBattery of questionnairesMood disordersLifetime diagnosisSubstance use disordersComorbid anxietyBingeAnxietyDiagnostic InterviewFunctioningUse disordersPsychopathologyPreliminary findingsPreliminary examinationInterview methodFamily historyDisordersParticipantsOverweight patientsPreliminary investigationCardiovascular disease risk reduction in patients with binge eating disorder and obesity: Randomized controlled trial of stepped-care versus standard behavioral weight loss
Grilo C. Cardiovascular disease risk reduction in patients with binge eating disorder and obesity: Randomized controlled trial of stepped-care versus standard behavioral weight loss. Atherosclerosis 2015, 241: e19. DOI: 10.1016/j.atherosclerosis.2015.04.081.Peer-Reviewed Original Research