2020
Joint American Academy of Dermatology–National Psoriasis Foundation guidelines of care for the management of psoriasis with systemic nonbiologic therapies
Menter A, Gelfand JM, Connor C, Armstrong AW, Cordoro KM, Davis DMR, Elewski BE, Gordon KB, Gottlieb AB, Kaplan DH, Kavanaugh A, Kiselica M, Kivelevitch D, Korman NJ, Kroshinsky D, Lebwohl M, Leonardi CL, Lichten J, Lim HW, Mehta NN, Paller AS, Parra SL, Pathy AL, Prater EF, Rahimi RS, Rupani RN, Siegel M, Stoff B, Strober BE, Tapper EB, Wong EB, Wu JJ, Hariharan V, Elmets CA. Joint American Academy of Dermatology–National Psoriasis Foundation guidelines of care for the management of psoriasis with systemic nonbiologic therapies. Journal Of The American Academy Of Dermatology 2020, 82: 1445-1486. PMID: 32119894, DOI: 10.1016/j.jaad.2020.02.044.Peer-Reviewed Original ResearchMeSH KeywordsAcitretinCyclosporineDrug MonitoringHumansMethotrexatePiperidinesPsoriasisPyrimidinesThalidomideConceptsDermatology–National Psoriasis Foundation guidelinesManagement of psoriasisTreatment of psoriasisChronic inflammatory diseaseFumaric acid estersMultiple organ systemsJoint American AcademyNonbiologic medicationsNonbiologic therapiesInflammatory diseasesFoundation guidelinesNew therapiesAmerican AcademyOrgan systemsMedicationsPsoriasisTherapyTreatmentDiseaseGuidelinesTofacitinibAcitretinPatientsApremilastPrescribers
2019
Joint American Academy of Dermatology–National Psoriasis Foundation guidelines of care for the management and treatment of psoriasis in pediatric patients
Menter A, Cordoro KM, Davis DMR, Kroshinsky D, Paller AS, Armstrong AW, Connor C, Elewski BE, Gelfand JM, Gordon KB, Gottlieb AB, Kaplan DH, Kavanaugh A, Kiselica M, Kivelevitch D, Korman NJ, Lebwohl M, Leonardi CL, Lichten J, Lim HW, Mehta NN, Parra SL, Pathy AL, Farley Prater E, Rupani RN, Siegel M, Stoff B, Strober BE, Wong EB, Wu JJ, Hariharan V, Elmets CA. Joint American Academy of Dermatology–National Psoriasis Foundation guidelines of care for the management and treatment of psoriasis in pediatric patients. Journal Of The American Academy Of Dermatology 2019, 82: 161-201. PMID: 31703821, DOI: 10.1016/j.jaad.2019.08.049.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdrenal Cortex HormonesAnthralinBiological ProductsCalcineurin InhibitorsCardiovascular DiseasesChildChild, PreschoolCoal TarComorbidityCyclosporineDermatologic AgentsDyslipidemiasEvidence-Based MedicineHumansInfantInfant, NewbornInflammatory Bowel DiseasesInsulin ResistanceMental HealthMetabolic SyndromeMethotrexateNicotinic AcidsObesityPhotochemotherapyPsoriasisRetinoidsConceptsPediatric patientsDermatology–National Psoriasis Foundation guidelinesTreatment of psoriasisImportant clinical questionsEvidence-based recommendationsJoint American AcademyPsoriasis managementInflammatory diseasesFoundation guidelinesClinical questionsPatientsAmerican AcademyPsoriasisProvider interactionsGuideline sectionsUnique physiologyGuidelinesPharmacokineticsDiseaseCareMultisystemUstekinumab Safety in Psoriasis, Psoriatic Arthritis, and Crohn’s Disease: An Integrated Analysis of Phase II/III Clinical Development Programs
Ghosh S, Gensler LS, Yang Z, Gasink C, Chakravarty SD, Farahi K, Ramachandran P, Ott E, Strober BE. Ustekinumab Safety in Psoriasis, Psoriatic Arthritis, and Crohn’s Disease: An Integrated Analysis of Phase II/III Clinical Development Programs. Drug Safety 2019, 42: 751-768. PMID: 30739254, PMCID: PMC6520311, DOI: 10.1007/s40264-019-00797-3.Peer-Reviewed Original ResearchConceptsPlacebo-treated patientsPsoriatic arthritisRegistrational trialsCrohn's diseaseMajor adverse cardiovascular eventsUstekinumab-treated patientsAdverse cardiovascular eventsSevere plaque psoriasisConsistent safety profileSevere Crohn's diseaseActive psoriatic arthritisClinical development programUstekinumab doseCardiovascular eventsPlaque psoriasisBiologic agentsPsoriatic patientsInduction doseSafety profileIncidence rateSafety dataPatientsDiseaseSafety eventsWeeks
2018
Methotrexate treatment of generalized granuloma annulare: a retrospective case series
Naka F, Strober B. Methotrexate treatment of generalized granuloma annulare: a retrospective case series. Journal Of Dermatological Treatment 2018, 29: 720-724. PMID: 29488435, DOI: 10.1080/09546634.2018.1447075.Peer-Reviewed Original ResearchConceptsGeneralized granuloma annulareRetrospective case seriesCase seriesMethotrexate treatmentGranuloma annulareAdverse effectsFirst-line therapyEfficacy of methotrexateMajority of patientsAvailable therapeutic modalitiesSmall case seriesIndividual case reportsLow internal validityDisease improvementInitial doseTreatment optionsCase reportComplete clearancePartial clearanceHair lossTherapeutic modalitiesPatientsSkin diseasesControl groupDisease severity
2016
Treatment of Moderate to Severe Pediatric Psoriasis: A Retrospective Case Series
Klufas D, Wald J, Strober B. Treatment of Moderate to Severe Pediatric Psoriasis: A Retrospective Case Series. Pediatric Dermatology 2016, 33: 142-149. PMID: 26871417, DOI: 10.1111/pde.12782.Peer-Reviewed Original ResearchConceptsSevere pediatric psoriasisRetrospective case seriesPediatric psoriasisCase seriesSevere psoriasisSystemic therapySide effectsDisease responseSimilar side effect profilePhysician Global Assessment scaleComprehensive safety profileSmall sample sizeSingle referral centerSubjective side effectsSide effect profileSafety of treatmentMultiple treatment optionsAdverse event occurrenceComparison of efficacyGlobal Assessment ScalePaucity of dataAdult psoriasisImmunomodulating therapiesAdverse eventsReferral center
2015
The Use of Methotrexate, Alone or in Combination With Other Therapies, for the Treatment of Palmoplantar Psoriasis.
Wald J, Klufas D, Strober B. The Use of Methotrexate, Alone or in Combination With Other Therapies, for the Treatment of Palmoplantar Psoriasis. Journal Of Drugs In Dermatology 2015, 14: 888-92. PMID: 26267735.Peer-Reviewed Original ResearchMeSH KeywordsAdalimumabAdolescentAdultAgedAged, 80 and overAnti-Inflammatory Agents, Non-SteroidalCyclosporineDermatologic AgentsDrug Therapy, CombinationEtanerceptFemaleFoot DermatosesHand DermatosesHumansImmunosuppressive AgentsInfliximabMaleMethotrexateMiddle AgedMycophenolic AcidPsoriasisSeverity of Illness IndexThalidomideUstekinumabYoung AdultCurrent and Future Oral Systemic Therapies for Psoriasis
Kelly J, Foley P, Strober B. Current and Future Oral Systemic Therapies for Psoriasis. Dermatologic Clinics 2015, 33: 91-109. PMID: 25412786, DOI: 10.1016/j.det.2014.09.008.Peer-Reviewed Original ResearchMeSH KeywordsAcitretinAnti-Inflammatory Agents, Non-SteroidalAntimetabolitesCyclosporineFumaratesHumansHydroxyureaImmunosuppressive AgentsIsoxazolesKeratolytic AgentsLeflunomideMethotrexateMycophenolic AcidPiperidinesProtein Kinase InhibitorsPsoriasisPyrimidinesPyrrolesSulfasalazineThalidomideThioguanine
2014
Methotrexate-Induced Liver Toxicity: Replacing the Liver Biopsy
Strober B. Methotrexate-Induced Liver Toxicity: Replacing the Liver Biopsy. JAMA Dermatology 2014, 150: 862-863. PMID: 24965863, DOI: 10.1001/jamadermatol.2014.681.Peer-Reviewed Original ResearchMethotrexate and cyclosporine in psoriasis revisited.
Strober B. Methotrexate and cyclosporine in psoriasis revisited. Seminars In Cutaneous Medicine And Surgery 2014, 33: s27-30. PMID: 24979542, DOI: 10.12788/j.sder.0066.Peer-Reviewed Original ResearchChanges in C‐reactive protein in patients with moderate‐to‐severe psoriasis switched to adalimumab therapy after suboptimal response to etanercept, methotrexate or phototherapy
Strober B, Poulin Y, Teller C, Wang Y, Williams D, Goldblum O. Changes in C‐reactive protein in patients with moderate‐to‐severe psoriasis switched to adalimumab therapy after suboptimal response to etanercept, methotrexate or phototherapy. Journal Of The European Academy Of Dermatology And Venereology 2014, 28: 1701-1706. PMID: 24422992, DOI: 10.1111/jdv.12372.Peer-Reviewed Original ResearchConceptsC-reactive proteinPrevious therapySuboptimal responseCRP reductionClinical responseAssociation of CRPNarrow-band ultraviolet B phototherapyBaseline C-reactive proteinC-reactive protein levelsInflammatory biomarker C-reactive proteinChronic plaque psoriasisUltraviolet B phototherapyBiomarkers C-reactive proteinAdalimumab therapyAdalimumab treatmentPlaque psoriasisSevere psoriasisB phototherapyBaseline characteristicsFinal visitObese patientsPsoriasis AreaPsoriatic arthritisNormal weightCRP decrease
2013
Management of psoriasis in pregnancy
Babalola O, Strober B. Management of psoriasis in pregnancy. Dermatologic Therapy 2013, 26: 285-292. PMID: 23914885, DOI: 10.1111/dth.12073.Peer-Reviewed Original Research
2012
A randomized, double‐blind, placebo‐controlled study to evaluate the addition of methotrexate to etanercept in patients with moderate to severe plaque psoriasis
Gottlieb A, Langley R, Strober B, Papp K, Klekotka P, Creamer K, Thompson E, Hooper M, Kricorian G. A randomized, double‐blind, placebo‐controlled study to evaluate the addition of methotrexate to etanercept in patients with moderate to severe plaque psoriasis. British Journal Of Dermatology 2012, 167: 649-657. PMID: 22533447, PMCID: PMC3504074, DOI: 10.1111/j.1365-2133.2012.11015.x.Peer-Reviewed Original ResearchConceptsSevere plaque psoriasisCombination therapyAdverse eventsWeek 24Etanercept monotherapyMonotherapy groupPlaque psoriasisWeek 12Necrosis factor inhibitor therapyStatic Physician's Global AssessmentGlobal assessmentMethotrexate combination therapyPhysician global assessmentPlacebo-controlled studySerious adverse eventsCombination therapy groupProportion of patientsAddition of methotrexatePASI 50PASI 75PASI 90Primary endpointSevere psoriasisAcceptable tolerabilityPsoriasis Area
2011
Methotrexate and psoriasis: Consensus conference
Kalb R, Strober B, Weinstein G, Lebwohl M. Methotrexate and psoriasis: Consensus conference. Journal Of The American Academy Of Dermatology 2011, 64: 1179. PMID: 21571176, DOI: 10.1016/j.jaad.2010.10.041.Peer-Reviewed Original ResearchSwitching to adalimumab for psoriasis patients with a suboptimal response to etanercept, methotrexate, or phototherapy: Efficacy and safety results from an open-label study
Strober B, Poulin Y, Kerdel F, Langley R, Gu Y, Gupta S, Okun M, Papp K. Switching to adalimumab for psoriasis patients with a suboptimal response to etanercept, methotrexate, or phototherapy: Efficacy and safety results from an open-label study. Journal Of The American Academy Of Dermatology 2011, 64: 671-681. PMID: 21414495, DOI: 10.1016/j.jaad.2010.03.009.Peer-Reviewed Original ResearchConceptsPhysician global assessmentSuboptimal responseSuboptimal therapyWeek 16Global assessmentPhase IIIb trialChronic plaque psoriasisOpen-label designOpen-label studyPrimary end pointPercentage of patientsNB-UVB phototherapySeverity Index scorePsoriasis clinical trialsTreatment of psoriasisDosage taperingIIIb trialPrior therapyPlaque psoriasisPsoriasis AreaPsoriasis flarePsoriasis patientsSafety profilePatient enrollmentClinical trialsSAPHO syndrome associated with hidradenitis suppurativa successfully treated with infliximab and methotrexate.
De Souza A, Solomon G, Strober B. SAPHO syndrome associated with hidradenitis suppurativa successfully treated with infliximab and methotrexate. Bulletin Of The NYU Hospital For Joint Disease 2011, 69: 185-7. PMID: 22035400.Peer-Reviewed Original ResearchConceptsHidradenitis suppurativaInflammatory musculoskeletal disordersPrevious ineffective treatmentRefractory SAPHO syndromeSafety of infliximabOral antibioticsComplete remissionSAPHO syndromeFirst doseCutaneous featuresContinued treatmentUnknown etiologyCase reportAcne vulgarisMusculoskeletal disordersIneffective treatmentInfliximabSkin abnormalitiesSyndromeYoung adultsSuppurativaJoint stiffnessTreatmentRemissionArthritis
2010
Disseminated superficial porokeratosis.
Brauer J, Mandal R, Walters R, Solomon G, Kundu R, Strober B. Disseminated superficial porokeratosis. Dermatology Online Journal 2010, 16: 20. PMID: 21163171, DOI: 10.5070/d395d16725.Peer-Reviewed Original ResearchConceptsPsoriatic arthritisSuperficial porokeratosisDiagnosis of porokeratosisOne-week historySetting of immunosuppressionDisseminated superficial porokeratosisCertolizumab pegolPruritic lesionsBiopsy specimenPorokeratosisArthritisDiagnosisPink spotsPegolImmunosuppressionPsoriasisMethotrexateTherapyLesionsExtremitiesWeeksWomen
2009
Methotrexate and psoriasis: 2009 National Psoriasis Foundation Consensus Conference
Kalb R, Strober B, Weinstein G, Lebwohl M. Methotrexate and psoriasis: 2009 National Psoriasis Foundation Consensus Conference. Journal Of The American Academy Of Dermatology 2009, 60: 824-837. PMID: 19389524, DOI: 10.1016/j.jaad.2008.11.906.Peer-Reviewed Original ResearchConceptsTreatment of psoriasisUse of methotrexateLiver biopsyNational Psoriasis Foundation Medical BoardAppropriate patient selectionNational Psoriasis FoundationEvidence-based studiesMedical boardsMethotrexate therapyPatient selectionRheumatoid arthritisTreatment optionsHepatic fibrosisRisk factorsConsensus conferencePsoriasisSide effectsEffective drugsLast guidelinesMethotrexateValuable optionTreatmentBiopsyTask ForceReport
2007
Folate with methotrexate: big benefit, questionable cost
Brownell I, Strober B. Folate with methotrexate: big benefit, questionable cost. British Journal Of Dermatology 2007, 157: 213-213. PMID: 17578449, DOI: 10.1111/j.1365-2133.2007.08005.x.Peer-Reviewed Original ResearchReconsidering liver biopsies during methotrexate therapy
Henning J, Gruson L, Strober B. Reconsidering liver biopsies during methotrexate therapy. Journal Of The American Academy Of Dermatology 2007, 56: 893-894. PMID: 17437899, DOI: 10.1016/j.jaad.2006.12.005.Peer-Reviewed Original Research
2006
Conventional systemic agents for psoriasis. A systematic review.
Strober B, Siu K, Menon K. Conventional systemic agents for psoriasis. A systematic review. The Journal Of Rheumatology 2006, 33: 1442-6. PMID: 16724368.Peer-Reviewed Original Research