2019
Urinary concentrations of phenols in association with biomarkers of oxidative stress in pregnancy: Assessment of effects independent of phthalates
Ferguson K, Lan Z, Yu Y, Mukherjee B, McElrath T, Meeker J. Urinary concentrations of phenols in association with biomarkers of oxidative stress in pregnancy: Assessment of effects independent of phthalates. Environment International 2019, 131: 104903. PMID: 31288179, PMCID: PMC6728185, DOI: 10.1016/j.envint.2019.104903.Peer-Reviewed Original ResearchMeSH Keywords8-Hydroxy-2'-DeoxyguanosineAdultBiomarkersBostonDinoprostFemaleHumansMaternal ExposureOxidative StressPhenolsPhthalic AcidsPregnancyProspective StudiesRegression AnalysisYoung AdultConceptsUrinary phthalate metabolitesOxidative stress biomarkersNon-null associationsPhthalate metabolitesBiomarkers of oxidative stressInterquartile rangeBenzophenone-3Associated with increasesOutcome biomarkersIncreased maternal oxidative stressStress biomarkersExposure to environmental phenolsOxidative stressReduced fetal growthUrinary oxidative stress biomarkersMaternal oxidative stressEffect estimatesAdaptive elastic net modelStudy populationPreterm birthFetal growthConcentration of phenolUrinary phenolPregnancyUrinary concentrations
2018
Associations between repeated ultrasound measures of fetal growth and biomarkers of maternal oxidative stress and inflammation in pregnancy
Ferguson K, Kamai E, Cantonwine D, Mukherjee B, Meeker J, McElrath T. Associations between repeated ultrasound measures of fetal growth and biomarkers of maternal oxidative stress and inflammation in pregnancy. American Journal Of Reproductive Immunology 2018, 80: e13017. PMID: 29984454, PMCID: PMC6160349, DOI: 10.1111/aji.13017.Peer-Reviewed Original ResearchConceptsAssociated with reduced fetal growthFetal growthAssociated with poorer childAdult health outcomesOxidative stress markersBirth cohort studyInterquartile rangeAssociated with head circumferenceRepeated-measures modelFetal weight z-scoreAssociated with fetal weightOxidative stressHealth outcomesStandard deviation decreaseWeight z-scoreStress markersSecondary analysisMaternal oxidative stressCohort studyZ-scoreFetal weightMaternal inflammationDeviation decreasePreterm birthHead circumference
2016
Repeated measures of inflammation and oxidative stress biomarkers in preeclamptic and normotensive pregnancies
Ferguson K, Meeker J, McElrath T, Mukherjee B, Cantonwine D. Repeated measures of inflammation and oxidative stress biomarkers in preeclamptic and normotensive pregnancies. American Journal Of Obstetrics And Gynecology 2016, 216: 527.e1-527.e9. PMID: 28043842, PMCID: PMC5420472, DOI: 10.1016/j.ajog.2016.12.174.Peer-Reviewed Original ResearchConceptsTumor necrosis factor-aNormotensive pregnanciesC-reactive proteinMeasures of inflammationHazard ratioOxidative stress biomarkersInterleukin-1bTime pointsInflammation biomarkersStudy visitsTime of preeclampsia diagnosisPrediction of preeclampsiaOxidative stressHigher body mass indexOxidative stress biomarker 8-isoprostaneStress biomarkersCox proportional hazards modelsCompared to other time pointsBody mass indexProspective birth cohortCalculate hazard ratiosSmall study populationPanel of inflammationFactor AProportional hazards modelRepeated measures analysis of associations between urinary bisphenol-A concentrations and biomarkers of inflammation and oxidative stress in pregnancy
Ferguson K, Cantonwine D, McElrath T, Mukherjee B, Meeker J. Repeated measures analysis of associations between urinary bisphenol-A concentrations and biomarkers of inflammation and oxidative stress in pregnancy. Reproductive Toxicology 2016, 66: 93-98. PMID: 27751756, PMCID: PMC5125888, DOI: 10.1016/j.reprotox.2016.10.002.Peer-Reviewed Original ResearchConceptsInterquartile range increaseBisphenol AOxidative stressRange increaseUrinary bisphenol A concentrationsC-reactive proteinBiomarkers of inflammationIL-6 concentrationsAdverse birth outcomesPrimary mechanism of actionAssociated with significant increasesRepeated measures analysisBisphenol A exposureBiomarkers of oxidative stressBisphenol A concentrationsMechanism of actionPregnant womenFetal developmentImpact pregnancyInflammation markersBirth outcomesOxidative stress biomarkersIL-6BPA exposurePregnancy
2014
Urinary Phthalate Metabolites and Biomarkers of Oxidative Stress in Pregnant Women: A Repeated Measures Analysis
Ferguson K, McElrath T, Chen Y, Mukherjee B, Meeker J. Urinary Phthalate Metabolites and Biomarkers of Oxidative Stress in Pregnant Women: A Repeated Measures Analysis. Environmental Health Perspectives 2014, 123: 210-216. PMID: 25402001, PMCID: PMC4348741, DOI: 10.1289/ehp.1307996.Peer-Reviewed Original ResearchConceptsUrinary phthalate metabolitesPhthalate metabolitesMono-n-butyl phthalateBiomarkers of oxidative stressBirth outcomesNested case-control study of preterm birthCase-control study of preterm birthPhthalate exposureStudy of preterm birthStudy of birth outcomesOxidative stressPopulation of pregnant womenNested case-control studyStudy population of pregnant womenAdverse birth outcomesUrine samplesMarkers of oxidative stressRepeated measures analysisHealth end pointsAssociated with significantly higher concentrationsDi(2-ethylhexyl) phthalatePreterm birthPregnant womenMono-n-butylLinear mixed modelsRepeated measures of urinary oxidative stress biomarkers during pregnancy and preterm birth
Ferguson K, McElrath T, Chen Y, Loch-Caruso R, Mukherjee B, Meeker J. Repeated measures of urinary oxidative stress biomarkers during pregnancy and preterm birth. American Journal Of Obstetrics And Gynecology 2014, 212: 208.e1-208.e8. PMID: 25111586, PMCID: PMC4312513, DOI: 10.1016/j.ajog.2014.08.007.Peer-Reviewed Original ResearchConceptsSpontaneous preterm birthPreterm birthAssociated with increased odds of spontaneous preterm birthCases of spontaneous preterm birthOdds of spontaneous preterm birthPathways to preterm birthMechanisms of preterm birthNested case-control studyLevels of 8-isoprostaneOxidative stressUrinary biomarkers of oxidative stressConcentrations of 8-isoprostaneUrinary oxidative stress biomarkersLevels of 8-OHdGMaternal oxidative stressCase-control studyProspective birth cohortUrinary 8-OHdG concentrationsAssociated with increased oddsInvestigate oxidative stressDelivered pretermBiomarkers of oxidative stressPlacental originUrinary concentrations of 8-isoprostanePreterm