2024
Residential exposure associations with ALS risk, survival, and phenotype: a Michigan-based case-control study
Goutman S, Boss J, Jang D, Piecuch C, Farid H, Batra M, Mukherjee B, Feldman E, Batterman S. Residential exposure associations with ALS risk, survival, and phenotype: a Michigan-based case-control study. Amyotrophic Lateral Sclerosis And Frontotemporal Degeneration 2024, 25: 543-553. PMID: 38557405, PMCID: PMC11269018, DOI: 10.1080/21678421.2024.2336110.Peer-Reviewed Original ResearchAmyotrophic lateral sclerosis riskAssociated with ALS riskALS riskCase-only analysisResidential settingsControl participantsCox proportional hazards modelsLogistic regression modelsCase-control studyMultinomial logistic regressionMultiple testing correctionProportional hazards modelLatent profile analysisResidential exposureExposure variablesPolytomous outcomesExposure associationsDecrease disease burdenALS susceptibilityLogistic regressionDisease burdenTesting correctionHazards modelRisk factorsRegression models
2022
Per- and Polyfluoroalkyl Substances and Incident Hypertension in Multi-Racial/Ethnic Women: The Study of Women's Health Across the Nation
Ding N, Karvonen-Gutierrez C, Mukherjee B, Calafat A, Harlow S, Park S. Per- and Polyfluoroalkyl Substances and Incident Hypertension in Multi-Racial/Ethnic Women: The Study of Women's Health Across the Nation. Hypertension 2022, 79: 1876-1886. PMID: 35695012, PMCID: PMC9308661, DOI: 10.1161/hypertensionaha.121.18809.Peer-Reviewed Original ResearchConceptsHazard ratioIncident hypertensionLowest tertileHighest tertileStudy of Women's HealthFree of hypertensionCalculate hazard ratiosAnnual follow-up visitsCardiovascular disease riskCox proportional hazards modelsQuantile g-computationWomen's cardiovascular disease riskWomen's HealthNo significant associationProportional hazards modelMidlife womenFollow-up visitG-computationDisease riskBlood pressure controlSerum concentrationsSignificant associationPositive associationHazards modelTertileHigh pre-diagnosis inflammation-related risk score associated with decreased ovarian cancer survival
Brieger KK, Phung MT, Mukherjee B, Bakulski KM, Anton-Culver H, Bandera EV, Bowtell DDL, Cramer DW, DeFazio A, Doherty JA, Fereday S, Fortner RT, Gentry-Maharaj A, Goode EL, Goodman MT, Harris HR, Matsuo K, Menon U, Modugno F, Moysich KB, Qin B, Ramus SJ, Risch HA, Rossing MA, Schildkraut JM, Trabert B, Vierkant RA, Winham SJ, Wentzensen N, Wu AH, Ziogas A, Khoja L, Cho KR, McLean K, Richardson J, Grout B, Chase A, Deurloo CM, Odunsi K, Nelson BH, Brenton JD, Terry KL, Pharaoh P, Berchuck A, Hanley GE, Webb PM, Pike MC, Pearce CL. High pre-diagnosis inflammation-related risk score associated with decreased ovarian cancer survival. Cancer Epidemiology Biomarkers & Prevention 2022, 31: cebp.epi-21-0977-a.2021. PMID: 34789471, PMCID: PMC9281656, DOI: 10.1158/1055-9965.epi-21-0977.Peer-Reviewed Original ResearchConceptsOvarian cancer survivalCox proportional hazards modelProportional hazards modelCancer survivalOvarian cancerRisk scoreHazards modelNonsteroidal anti-inflammatory drug useAnti-inflammatory drug useMenopausal hormone therapy useEnvironmental tobacco smoke exposureInvasive epithelial ovarian cancerHormone therapy usePelvic inflammatory diseaseInflammation-related factorsPolycystic ovarian syndromeTobacco smoke exposureBody mass indexRisk of deathEpithelial ovarian cancerOvarian Cancer Association ConsortiumOvarian cancer diagnosisHigh death rateAspirin useOvarian syndrome
2021
Urinary metals and metal mixtures and timing of natural menopause in midlife women: The Study of Women’s Health Across the Nation
Wang X, Ding N, Harlow S, Randolph J, Mukherjee B, Gold E, Park S. Urinary metals and metal mixtures and timing of natural menopause in midlife women: The Study of Women’s Health Across the Nation. Environment International 2021, 157: 106781. PMID: 34311223, PMCID: PMC8490279, DOI: 10.1016/j.envint.2021.106781.Peer-Reviewed Original ResearchConceptsMetal mixturesMetal concentrationsTiming of natural menopauseCox proportional hazards modelsNatural menopauseStudy of Women's HealthProportional hazards modelHazard ratioEnvironmental risk scoreLowest quartileIndividual metal concentrationsExposure to metalsUrinary metal concentrationsHazards modelMedian follow-upMonths of amenorrheaWomen's HealthAssociated with earlier natural menopauseEarly natural menopauseUrinary metalsNation Multi-Pollutant StudyBleeding episodesHormone therapyPremenopausal womenMedian age
2020
Menopausal hormone therapy prior to the diagnosis of ovarian cancer is associated with improved survival
Brieger KK, Peterson S, Lee AW, Mukherjee B, Bakulski KM, Alimujiang A, Anton-Culver H, Anglesio MS, Bandera EV, Berchuck A, Bowtell DDL, Chenevix-Trench G, Cho KR, Cramer DW, DeFazio A, Doherty JA, Fortner RT, Garsed DW, Gayther SA, Gentry-Maharaj A, Goode EL, Goodman MT, Harris HR, Høgdall E, Huntsman DG, Shen H, Jensen A, Johnatty SE, Jordan SJ, Kjaer SK, Kupryjanczyk J, Lambrechts D, McLean K, Menon U, Modugno F, Moysich K, Ness R, Ramus SJ, Richardson J, Risch H, Rossing MA, Trabert B, Wentzensen N, Ziogas A, Terry KL, Wu AH, Hanley GE, Pharoah P, Webb PM, Pike MC, Pearce CL, Consortium F. Menopausal hormone therapy prior to the diagnosis of ovarian cancer is associated with improved survival. Gynecologic Oncology 2020, 158: 702-709. PMID: 32641237, PMCID: PMC7487048, DOI: 10.1016/j.ygyno.2020.06.481.Peer-Reviewed Original ResearchConceptsMenopausal hormone therapyOvarian cancer survivalMHT useResidual diseaseHormone therapyCancer survivalOvarian cancerHigh-grade serous carcinomaMacroscopic residual diseaseHormone therapy useFavorable prognostic factorPost-menopausal womenOvarian Cancer Association ConsortiumProportional hazards modelRecency of useImproved survivalPrognostic factorsTherapy useSerous carcinomaOvarian carcinomaHazards modelSmall studyAdvanced stageLarger studyLogistic regression