2024
Adverse cardiovascular events and cardiac imaging findings in patients on immune checkpoint inhibitors
Kwan J, Shen M, Akhlaghi N, Hu J, Mora R, Cross J, Jiang M, Mankbadi M, Wang P, Zaman S, Lee S, Im Y, Feher A, Liu Y, S. S, Tao W, Wei W, Baldassarre L. Adverse cardiovascular events and cardiac imaging findings in patients on immune checkpoint inhibitors. PLOS ONE 2024, 19: e0314555. PMID: 39621799, PMCID: PMC11611253, DOI: 10.1371/journal.pone.0314555.Peer-Reviewed Original ResearchConceptsAdverse cardiovascular eventsICI therapyCardiac magnetic resonanceIncreased risk of mortalityICI initiationIncreased riskRisk of mortalityCentral nervous systemVentricular dysfunctionCancer patients treated with ICIsCardiovascular eventsLeft ventricular late gadolinium enhancementMortality benefitCardiovascular riskAbnormal left ventricular ejection fractionPatients treated with ICIsLeft ventricular ejection fractionCentral nervous system malignanciesRisk of adverse cardiovascular eventsImmune checkpoint inhibitorsRight ventricular dysfunctionGlobal longitudinal strainVentricular ejection fractionLeft ventricular dysfunctionMultimodality cardiac imaging
2022
Over the Edge What Can Imaging Tell Us When the Ejection Fraction Is “Supranormal”? ∗
Feher A, Meadows J. Over the Edge What Can Imaging Tell Us When the Ejection Fraction Is “Supranormal”? ∗. JACC Heart Failure 2022, 10: 595-597. PMID: 35902164, DOI: 10.1016/j.jchf.2022.06.004.Peer-Reviewed Original Research
2017
Quantitative Assessment of Coronary Microvascular Function
Feher A, Sinusas AJ. Quantitative Assessment of Coronary Microvascular Function. Circulation Cardiovascular Imaging 2017, 10: e006427. PMID: 28794138, PMCID: PMC5678979, DOI: 10.1161/circimaging.117.006427.Peer-Reviewed Original ResearchMeSH KeywordsComputed Tomography AngiographyCoronary AngiographyCoronary CirculationEchocardiographyHeart DiseasesHumansMagnetic Resonance ImagingMicrocirculationMyocardial Perfusion ImagingPositron-Emission TomographyPredictive Value of TestsPrognosisReproducibility of ResultsTomography, Emission-Computed, Single-PhotonConceptsCoronary microvascular dysfunctionMyocardial blood flowMicrovascular dysfunctionBlood flowMyocardial perfusionCoronary microvascular impairmentCoronary microvascular functionEpicardial coronary arteriesNormal myocardial perfusionMyocardial contrast echocardiographyAbsolute myocardial blood flowImportant prognostic relevanceMagnetic resonance imagingPositron emission tomographySingle photon emissionMicrovascular impairmentMicrovascular functionMultiple imaging modalitiesPrognostic relevanceCoronary arteryCoronary flowCoronary perfusionContrast echocardiographyClinical valueFunctional microcirculation
2016
Echocardiographic Linear Dimensions for Assessment of Right Ventricular Chamber Volume as Demonstrated by Cardiac Magnetic Resonance
Kim J, Srinivasan A, Seoane T, Di Franco A, Peskin CS, McQueen DM, Paul TK, Feher A, Geevarghese A, Rozenstrauch M, Devereux RB, Weinsaft JW. Echocardiographic Linear Dimensions for Assessment of Right Ventricular Chamber Volume as Demonstrated by Cardiac Magnetic Resonance. Journal Of The American Society Of Echocardiography 2016, 29: 861-870. PMID: 27297619, PMCID: PMC5057385, DOI: 10.1016/j.echo.2016.05.002.Peer-Reviewed Original ResearchConceptsRV end-diastolic volumeCardiac magnetic resonanceEnd-diastolic volumeRV end-systolic volumeEnd-systolic volumeRV lengthEchocardiographic dimensionsEnd-systolic dimensionCoronary artery diseaseRight ventricular structureRV chamber sizeAmerican SocietyVentricular chamber volumeRetrospective registryRV dilationArtery diseaseRV sizeRV dimensionsObtainable markerVentricular structureRV volumesEchocardiographyMagnetic resonanceFour-chamberAxis viewAssociation of Right Ventricular Pressure and Volume Overload with Non-Ischemic Septal Fibrosis on Cardiac Magnetic Resonance
Kim J, Medicherla CB, L. C, Feher A, Kukar N, Geevarghese A, Goyal P, Horn E, Devereux RB, Weinsaft JW. Association of Right Ventricular Pressure and Volume Overload with Non-Ischemic Septal Fibrosis on Cardiac Magnetic Resonance. PLOS ONE 2016, 11: e0147349. PMID: 26799498, PMCID: PMC4723145, DOI: 10.1371/journal.pone.0147349.Peer-Reviewed Original ResearchConceptsPulmonary artery systolic pressureNon-ischaemic fibrosisCardiac magnetic resonanceRV dysfunctionAdverse right ventricular (RV) remodelingRV end-systolic volumeWall stressRV pressure loadRV wall stressRight ventricular remodelingRight ventricular pressureEnd-systolic volumeLower RVEFSimilar LVEFLV dysfunctionRV dilationRV sizeSeptal fibrosisMultivariable analysisSystolic pressureVolume overloadChamber dilationPoor prognosisTransthoracic echoVentricular remodeling
2015
Myocardial perfusion pattern for stratification of ischemic mitral regurgitation response to percutaneous coronary intervention
Goyal P, Kim J, Feher A, L. C, Gurevich S, Veal DR, Szulc M, Wong FJ, Ratcliffe MB, Levine RA, Devereux RB, Weinsaft JW. Myocardial perfusion pattern for stratification of ischemic mitral regurgitation response to percutaneous coronary intervention. Coronary Artery Disease 2015, 26: 642-650. PMID: 26049923, PMCID: PMC4631658, DOI: 10.1097/mca.0000000000000271.Peer-Reviewed Original ResearchMeSH KeywordsAgedAged, 80 and overCardiac-Gated Single-Photon Emission Computer-Assisted TomographyEchocardiographyExercise TestFemaleHeartHumansLogistic ModelsMaleMiddle AgedMitral Valve InsufficiencyMultivariate AnalysisMyocardial InfarctionMyocardial Perfusion ImagingPercutaneous Coronary InterventionRisk AssessmentStroke VolumeConceptsPercutaneous coronary interventionMyocardial perfusion imagingAdvanced mitral regurgitationMitral regurgitationMyocardial perfusionCoronary interventionPerfusion defectsLV volumesStress/rest myocardial perfusionLeft ventricular (LV) chamber dilationVentricular chamber dilationAbnormal myocardial perfusionMild mitral regurgitationPerfusion defect sizeIschemic mitral regurgitationMyocardial perfusion patternsRest myocardial perfusionSingle photon emissionTransthoracic echocardiographyChamber dilationPerfusion deficitsPerfusion patternsMR severityRest scorePerfusion differences