2024
Positron Emission Tomography in the Diagnosis and Management of Cardiac Allograft Vasculopathy
Csecs I, Yakkali S, Feher A. Positron Emission Tomography in the Diagnosis and Management of Cardiac Allograft Vasculopathy. Current Cardiovascular Imaging Reports 2024, 17: 85-92. DOI: 10.1007/s12410-024-09595-7.Peer-Reviewed Original ResearchManagement of CAVPositron emission tomography myocardial perfusion imagingCardiac allograft vasculopathyInvasive coronary angiographyMyocardial perfusion imagingMyocardial flow reservePositron emission tomographyHeart transplant recipientsMyocardial blood flowAllograft vasculopathyTransplant recipientsPET-derived MBFInternational Society for Heart and Lung Transplantation guidelinesCAV detectionAlternative to invasive coronary angiographyEfficacy of positron emission tomographyRoutine surveillance protocolEmission tomographyClass IIa indicationFrequent invasive proceduresReduce radiation exposurePositron emission tomography imagingPrognostic valueCoronary angiographyMulticenter study
2019
Molecular Imaging Targets in Heart Failure and Left Ventricular Remodeling
Boutagy N, Feher A, Sikanderkhel S, Sinusas A. Molecular Imaging Targets in Heart Failure and Left Ventricular Remodeling. 2019, 405-435. DOI: 10.1002/9781118754467.ch13.ChaptersHeart failureManagement of HFMultimodality cardiovascular imagingMolecular imaging targetsMagnetic resonance imagingPositron emission tomographySingle photon emissionExtracellular matrix depositionCardiac injuryVentricle remodelingVentricular remodelingStandard clinical toolResonance imagingEmission tomographyClinical toolCompensatory mechanismsCardiac perfusionCardiovascular imagingNuclear imaging modalitiesImaging modalitiesImaging targetsPhoton emissionMatrix depositionNoninvasive measurementMolecular imagingMolecular Imaging of the Heart
Boutagy NE, Feher A, Alkhalil I, Umoh N, Sinusas AJ. Molecular Imaging of the Heart. 2019, 9: 477-533. PMID: 30873600, DOI: 10.1002/cphy.c180007.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsConceptsCardiovascular diseaseRisk stratificationCardiovascular molecular imagingMultimodality cardiovascular imagingIschemic heart failureMolecular imagingMolecular imaging targetsPositron emission tomographySingle photon emissionNumerous cardiovascular diseasesClinical molecular imagingEjection fractionHeart failureMedical therapySystemic diseaseMyocardial infarctionPathophysiological changesCardiac functionEarly diagnosisDisease processCardiac arrhythmiasEmission tomographyCardiovascular imagingImaging strategiesPhoton emission
2018
Serial Assessment of Coronary Flow Reserve by Rubidium-82 Positron Emission Tomography Predicts Mortality in Heart Transplant Recipients
Feher A, Srivastava A, Quail MA, Boutagy NE, Khanna P, Wilson L, Miller EJ, Liu YH, Lee F, Sinusas AJ. Serial Assessment of Coronary Flow Reserve by Rubidium-82 Positron Emission Tomography Predicts Mortality in Heart Transplant Recipients. JACC Cardiovascular Imaging 2018, 13: 109-120. PMID: 30343093, PMCID: PMC6461525, DOI: 10.1016/j.jcmg.2018.08.025.Peer-Reviewed Original ResearchMeSH KeywordsAgedCoronary Artery DiseaseFemaleFractional Flow Reserve, MyocardialHeart TransplantationHumansMaleMiddle AgedMyocardial Perfusion ImagingPositron-Emission TomographyPredictive Value of TestsProspective StudiesRadiopharmaceuticalsReproducibility of ResultsRubidium RadioisotopesTime FactorsTreatment OutcomeConceptsPositron emission tomographyLong-term prognostic valueSerial assessmentPET-2Pet-1Cause mortalityHT patientsPrognostic valueHigh CFRLow CFRRb positron-emission tomographyEmission tomographyRb-82 positron emission tomographyRubidium-82 positron emission tomographyPET imagingHeart transplantation patientsHistory of HTCardiac allograft vasculopathyHeart transplant recipientsLong-term mortalitySingle-center studyMultivariate Cox regressionCoronary flow reserveAllograft vasculopathyHT recipients
2017
Quantitative Assessment of Coronary Microvascular Function
Feher A, Sinusas AJ. Quantitative Assessment of Coronary Microvascular Function. Circulation Cardiovascular Imaging 2017, 10: e006427. PMID: 28794138, PMCID: PMC5678979, DOI: 10.1161/circimaging.117.006427.Peer-Reviewed Original ResearchMeSH KeywordsComputed Tomography AngiographyCoronary AngiographyCoronary CirculationEchocardiographyHeart DiseasesHumansMagnetic Resonance ImagingMicrocirculationMyocardial Perfusion ImagingPositron-Emission TomographyPredictive Value of TestsPrognosisReproducibility of ResultsTomography, Emission-Computed, Single-PhotonConceptsCoronary microvascular dysfunctionMyocardial blood flowMicrovascular dysfunctionBlood flowMyocardial perfusionCoronary microvascular impairmentCoronary microvascular functionEpicardial coronary arteriesNormal myocardial perfusionMyocardial contrast echocardiographyAbsolute myocardial blood flowImportant prognostic relevanceMagnetic resonance imagingPositron emission tomographySingle photon emissionMicrovascular impairmentMicrovascular functionMultiple imaging modalitiesPrognostic relevanceCoronary arteryCoronary flowCoronary perfusionContrast echocardiographyClinical valueFunctional microcirculation