Featured Publications
Classification of Patients for Whom Benefit of Long-term Opioid Therapy No Longer Outweighs Harm: Protocol for a Delphi Study
Van Cleve R, Edmond S, Snow J, Black AC, Pomeranz JL, Becker W. Classification of Patients for Whom Benefit of Long-term Opioid Therapy No Longer Outweighs Harm: Protocol for a Delphi Study. JMIR Research Protocols 2022, 11: e33310. PMID: 35254277, PMCID: PMC8933798, DOI: 10.2196/33310.Peer-Reviewed Original ResearchLong-term opioid therapyINTERNATIONAL REGISTERED REPORT IDENTIFIERNew diagnostic entityDiagnostic entityOpioid therapySubset of patientsOpioid use disorderClassification of patientsInternal Review BoardChronic painOutweigh harmsClinical guidancePossible diagnostic criteriaDiagnostic criteriaUse disordersPatientsDelphi studyVeterans AffairsReview boardTherapyClinical phenomenaArt ConferenceThird roundDelphi techniqueParticipantsInitial development of patient-reported instrument assessing harm, efficacy, and misuse of long-term opioid therapy
Becker WC, Fiellin DA, Black AC, Kostovich CT, Kerns RD, Fraenkel L. Initial development of patient-reported instrument assessing harm, efficacy, and misuse of long-term opioid therapy. The Journal Of Rehabilitation Research And Development 2016, 53: 127-136. PMID: 27006339, PMCID: PMC4806533, DOI: 10.1682/jrrd.2014.11.0285.Peer-Reviewed Original ResearchConceptsLong-term opioid therapyPatient-reported instrumentOpioid therapyFurther item reductionIneffective medicationsClinical outcomesPrimary careFrequent reassessmentPatient comprehensionItem reductionGold standardEfficacyTherapyInterdisciplinary teamLevel checksCognitive interviewsMisuseHarmMedicationsPatientsLong-term opioid therapy trajectories and overdose in patients with and without cancer.
Merlin J, Black A, Midboe A, Troszak L, Asch S, Bohnert A, Fenton B, Giannitrapani K, Glassman P, Kerns R, Silveira M, Lorenz K, Abel E, Becker W. Long-term opioid therapy trajectories and overdose in patients with and without cancer. BMJ Oncology 2023, 2: e000023. PMID: 38259328, PMCID: PMC10802123, DOI: 10.1136/bmjonc-2022-000023.Peer-Reviewed Original ResearchLong-term opioid therapyVeterans Health Administration databaseRetrospective cohort studyCornerstone of managementOpioid overdose riskHealth Administration databaseOpioid-related overdosesPresence of cancerRole of cancerOpioid receiptOpioid therapyCohort studyConclusions PatientsMost patientsObjective painOpioid risksDose/Opioid overdoseOverdose riskInternational ClassificationLower riskPatientsEffect of trajectoriesCancerAdministration database
2024
Clinician and Practice Characteristics Associated With Support of Office-Based Methadone: Findings From a National Survey.
Sung M, Black A, Blevins D, Henry B, Cates-Wessel K, Dawes M, Hagle H, Joudrey P, Molfenter T, Levin F, Fiellin D, Edelman E. Clinician and Practice Characteristics Associated With Support of Office-Based Methadone: Findings From a National Survey. Journal Of Addiction Medicine 2024 PMID: 39475119, DOI: 10.1097/adm.0000000000001388.Peer-Reviewed Original ResearchOpioid use disorderCharacteristics associated with supportTreatment of opioid use disorderMultivariate logistic regression modelOffice-based settingSequential multivariable logistic regression modelsOpioid treatment programsLogistic regression modelsAcademic medical centerUse disorderInclusion criteriaMethadoneMedical CenterPatientsOffice-basedCOVID-19 surveyClinician supportPractice characteristicsLongitudinal treatmentImplementation barriersPolicy changesMOUDOutcome variablesImprove accessNational survey
2022
Delphi study to explore a new diagnosis for “ineffective” long-term opioid therapy for chronic pain
Edmond S, Snow J, Pomeranz J, Van Cleve R, Black A, Compton P, Becker W. Delphi study to explore a new diagnosis for “ineffective” long-term opioid therapy for chronic pain. Pain 2022, 164: 870-876. PMID: 36448976, DOI: 10.1097/j.pain.0000000000002783.Peer-Reviewed Original ResearchConceptsLong-term opioid therapyNew diagnostic entityDiagnostic criteriaPotential diagnostic criteriaDiagnostic entityOpioid therapyChronic painOpioid use disorderCertain patientsNew diagnosisUse disordersDelphi studyPainDisorder criteriaSubgroup of expertsRound 2PatientsTherapyThree-quartersRefining criteriaDelphi panelistsExpert panelistsSubgroupsLikert-type scaleRapid qualitative analysisLong-term Opioid Therapy and Overdose in Patients with and without Cancer
Merlin J, Black A, Midboe A, Troszak L, Asch S, Bohnert A, Fenton B, Giannitrapani K, Glassman P, Kerns R, Silveira M, Lorenz K, Becker W. Long-term Opioid Therapy and Overdose in Patients with and without Cancer. Journal Of Pain 2022, 23: 60. DOI: 10.1016/j.jpain.2022.03.225.Peer-Reviewed Original ResearchLong-term opioid therapyOpioid therapyCox proportional hazard modelingElectronic health record databaseCancer pain managementRetrospective cohort studyProportional hazard modelingOpioid overdose riskHealth record databasePresence of cancerRole of cancerOpioid receiptCohort entryCohort studyHazard ratioMost patientsPain managementOpioid risksDose/Inclusion criteriaOpioid overdoseOverdose riskLatent growth mixture modelingLower riskPatients