2024
Surgical treatment and outcomes in aortic valve endocarditis and perivalvular abscesses
Degife E, Morrison A, Mahmood S, Ragnarsson S, Amabile A, Assi R, Vallabjoyshula P, Geirsson A. Surgical treatment and outcomes in aortic valve endocarditis and perivalvular abscesses. Scientific Reports 2024, 14: 29373. PMID: 39592664, PMCID: PMC11599902, DOI: 10.1038/s41598-024-79256-8.Peer-Reviewed Original ResearchMeSH KeywordsAbscessAdultAgedAortic ValveAortic Valve DiseaseEndocarditisEndocarditis, BacterialFemaleHumansMaleMiddle AgedRetrospective StudiesTreatment OutcomeConceptsAortic root abscessAortic valve endocarditisProsthetic valve endocarditisRoot abscessValve endocarditisPerivalvular abscessSurgical treatmentIncreased morbidityAortic valve infective endocarditisPredictors of operative mortalityActive aortic valve endocarditisFive-year survivalPresence of abscessAortocavitary fistulaeEndocarditis surgeryOperative mortalityRoot replacementInfective endocarditisCardiac surgeryPerioperative characteristicsPreoperative imagingHeart blockRepair groupEndocarditisComplex repair
2022
Impact of secondary mitral regurgitation on survival in atrial and ventricular dysfunction
Mori M, Zogg C, Amabile A, Fereydooni S, Agarwal R, Weininger G, Krane M, Sugeng L, Geirsson A. Impact of secondary mitral regurgitation on survival in atrial and ventricular dysfunction. PLOS ONE 2022, 17: e0277385. PMID: 36548259, PMCID: PMC9778994, DOI: 10.1371/journal.pone.0277385.Peer-Reviewed Original ResearchMeSH KeywordsAgedAtrial FibrillationEchocardiographyFemaleHumansMaleMitral Valve InsufficiencyRetrospective StudiesTreatment OutcomeVentricular Dysfunction, LeftConceptsSecondary mitral regurgitationVentricular dysfunctionHazard of deathAtrial dysfunctionMitral regurgitationMild secondary mitral regurgitationSevere secondary mitral regurgitationCox proportional hazards modelRisk-adjusted hazardRetrospective cohort studySurvival of patientsProportional hazards modelCohort studyPatient demographicsSeverity strataBetter survivalHazards modelPatientsDysfunctionNatural historyPropensity scoreSeverityDifferent severitySurvivalRegurgitationVariability in surveillance practice for patients with diagnosis of bicuspid aortic valve syndrome
Kahler-Quesada A, Vallabhajosyula I, Yousef S, Mori M, Amabile A, Assi R, Geirsson A, Vallabhajosyula P. Variability in surveillance practice for patients with diagnosis of bicuspid aortic valve syndrome. Scientific Reports 2022, 12: 22009. PMID: 36539583, PMCID: PMC9768129, DOI: 10.1038/s41598-022-25571-x.Peer-Reviewed Original ResearchMeSH KeywordsAdultAgedAortaAortic ValveBicuspid Aortic Valve DiseaseEchocardiographyFemaleHeart Valve DiseasesHumansMaleMiddle AgedRetrospective StudiesSyndromeConceptsBicuspid aortic valveTertiary care centerAortic valveCare centerCardiovascular specialistsBicuspid aortic valve syndromeAortic pathologySurveillance imagingDisease progressionPatientsBivariate analysisEchocardiogramGuide interventionDiagnosisHigher proportionValveSurveillance practicesUrgent needGuidelinesValvulopathySpecialistsSurgeryValvularSyndromeFollow
2021
Transit time flow measurement of coronary bypass grafts before and after protamine administration
Leviner DB, von Mücke Similon M, Rosati CM, Amabile A, Thuijs DJFM, Giammarco GD, Wendt D, Trachiotis GD, Kieser TM, Kappetein AP, Head SJ, Taggart DP, Puskas JD. Transit time flow measurement of coronary bypass grafts before and after protamine administration. Journal Of Cardiothoracic Surgery 2021, 16: 195. PMID: 34243799, PMCID: PMC8268198, DOI: 10.1186/s13019-021-01575-y.Peer-Reviewed Original ResearchConceptsTransit-time flow measurementProtamine administrationTTFM parametersSingle graftAdministration of protamineCoronary bypass graftsSpecific clinical situationsGraft quality assessmentCoronary surgeryCABG proceduresBypass graftGraft assessmentVenous conduitsMethodsThe databaseIntraoperative changesGraft performanceClinical situationsGraftMixed graftAdministrationGraft analysisCoupling indexMAP rangeSmall increaseFlow measurementsSurvival of Patients With Mild Secondary Mitral Regurgitation With and Without Mild Tricuspid Regurgitation
Mori M, Weininger G, Agarwal R, Shang M, Amabile A, Kahler-Quesada A, Yousef S, Pichert M, Vallabhajosyula P, Zhang Y, Sugeng L, Geirsson A. Survival of Patients With Mild Secondary Mitral Regurgitation With and Without Mild Tricuspid Regurgitation. Canadian Journal Of Cardiology 2021, 37: 1513-1521. PMID: 34119634, DOI: 10.1016/j.cjca.2021.06.005.Peer-Reviewed Original ResearchConceptsMild secondary mitral regurgitationLeft ventricular ejection fractionSecondary mitral regurgitationMild tricuspid regurgitationNormal left ventricular ejection fractionTricuspid regurgitationHazard of deathGroup 1Valvular abnormalitiesMitral regurgitationGroup 2Mean age 61 yearsGroup 4Cox proportional hazards modelGroup 1 patientsGroup 2 patientsGroup 3 patientsGroup 4 patientsAge 61 yearsRetrospective cohort studySurvival of patientsSubgroup of patientsProportional hazards modelCohort studyHealth care network