2018
Reduced Cancer Survival Among Adults With HIV and AIDS-Defining Illnesses Despite No Difference in Cancer Stage at Diagnosis
Grover S, Desir F, Jing Y, Bhatia RK, Trifiletti DM, Swisher-McClure S, Kobie J, Moore RD, Rabkin CS, Silverberg MJ, Salters K, Mathews WC, Gill MJ, Thorne JE, Castilho J, Kitahata MM, Justice A, Horberg MA, Achenbach CJ, Mayor AM, Althoff KN. Reduced Cancer Survival Among Adults With HIV and AIDS-Defining Illnesses Despite No Difference in Cancer Stage at Diagnosis. JAIDS Journal Of Acquired Immune Deficiency Syndromes 2018, 79: 421-429. PMID: 30211722, PMCID: PMC6203623, DOI: 10.1097/qai.0000000000001842.Peer-Reviewed Original ResearchConceptsLung cancer diagnosisCancer diagnosisLung cancerCancer stageNorth American AIDS Cohort CollaborationAdjusted mortality rate ratioHodgkin lymphoma diagnosisOnly lung cancerRole of HIVRisk of deathMortality rate ratiosCohort CollaborationImmune dysfunctionCervical cancerImmune suppressionCancer outcomesSignificant immunosuppressionCancer survivalPoor survivalLymphoma diagnosisMortality rateProbability of survivalPWHHigh mortalityCancer
2017
HIV Infection, Immunosuppression, and Age at Diagnosis of Non-AIDS-Defining Cancers
Shiels MS, Althoff KN, Pfeiffer RM, Achenbach CJ, Abraham AG, Castilho J, Cescon A, D’Souza G, Dubrow R, Eron JJ, Gebo K, Gill M, Goedert JJ, Grover S, Hessol NA, Justice A, Kitahata M, Mayor A, Moore RD, Napravnik S, Novak RM, Thorne JE, Silverberg MJ, Engels EA, AIDS F. HIV Infection, Immunosuppression, and Age at Diagnosis of Non-AIDS-Defining Cancers. Clinical Infectious Diseases 2017, 64: 468-475. PMID: 27940936, PMCID: PMC5850313, DOI: 10.1093/cid/ciw764.Peer-Reviewed Original ResearchConceptsOral cavity/pharynxYounger ageCancer diagnosisCD4 countMedian ageLung cancerKidney cancerGeneral populationNorth American AIDS Cohort CollaborationMost cancersEnd Results ProgramHuman immunodeficiency virusRisk factor exposureLung cancer diagnosisAccelerated cancer progressionCohort CollaborationNon-AIDSAnal cancerHIV infectionImmunodeficiency virusResults ProgramMyeloma diagnosisPLWHAIDS statusCancer