2021
Commentary: Treatment-resistant Depression: Considerations Related to ECT and Ketamine
Garakani A. Commentary: Treatment-resistant Depression: Considerations Related to ECT and Ketamine. Journal Of Psychiatric Practice 2021, 27: 496-497. PMID: 34768276, DOI: 10.1097/pra.0000000000000593.Commentaries, Editorials and LettersConceptsTreatment-resistant depressionElectroconvulsive therapyLiver transplantationChronic treatment-resistant depressionUse of ECTMaintenance electroconvulsive therapyMajor depressive episodeBitemporal treatmentsIntranasal formsIntranasal ketaminePartial responsePrescribed antipsychoticsAdjunctive treatmentAntirejection medicationsChronic migraineMigraine medicationsECT treatmentComorbid migraineDepressive episodePsychotic featuresOrgan transplantationKetamine abuseBrain stimulationClinical considerationsPatientsCommentary: Psychiatric Presentations of Nonpsychiatric Illness or Treatment
Garakani A. Commentary: Psychiatric Presentations of Nonpsychiatric Illness or Treatment. Journal Of Psychiatric Practice 2021, 27: 404-405. PMID: 34529609, DOI: 10.1097/pra.0000000000000577.Commentaries, Editorials and LettersConceptsManic symptomsPsychiatric historyPerinatal brain injuryOff-label useExamples of patientsPsychogenic nauseaRefractory nauseaGastroesophageal refluxAtypical presentationMood stabilizersSubdural hematomaCertain patientsMedical historyPsychiatric presentationsBrain injuryVisual hallucinationsMedical disordersPsychiatric symptomsPatientsNonpsychiatric illnessCognitive deficitsSuicidal thinkingSymptomsTraditional treatmentBrain imagingImpact of Childhood Trauma Histories Versus Recent Trauma Symptoms on Affective Lability in Adult Bipolar Disorder.
Garakani A, Buono FD, Larkin K, Goldberg JF. Impact of Childhood Trauma Histories Versus Recent Trauma Symptoms on Affective Lability in Adult Bipolar Disorder. The Journal Of Clinical Psychiatry 2021, 82 PMID: 34406718, DOI: 10.4088/jcp.21br13912.Peer-Reviewed Original ResearchCommentary: Diagnostic Challenges in Evaluating Adolescents
Garakani A. Commentary: Diagnostic Challenges in Evaluating Adolescents. Journal Of Psychiatric Practice 2021, 27: 239-240. PMID: 33939380, DOI: 10.1097/pra.0000000000000553.Commentaries, Editorials and LettersConceptsDiagnostic challengeConstellation of symptomsProminent mood symptomsPosttraumatic stress disorderFemale patientsTrauma-related symptomsMedication treatmentAntipsychotic medicationAdolescent patientsUnnecessary treatmentVisual hallucinationsDifferential diagnosisPatient reportsTerms of stigmaMood symptomsDepressive symptomsPsychotic symptomsSide effectsPatientsPsychotic disordersSuicidal ideasFull differential diagnosisAuditory hallucinationsCotard's syndromeIncorrect diagnosisNeurological manifestations as the predictors of severity and mortality in hospitalized individuals with COVID-19: a multicenter prospective clinical study
Amanat M, Rezaei N, Roozbeh M, Shojaei M, Tafakhori A, Zoghi A, Darazam IA, Salehi M, Karimialavijeh E, Lima BS, Garakani A, Vaccaro A, Ramezani M. Neurological manifestations as the predictors of severity and mortality in hospitalized individuals with COVID-19: a multicenter prospective clinical study. BMC Neurology 2021, 21: 116. PMID: 33726699, PMCID: PMC7960879, DOI: 10.1186/s12883-021-02152-5.Peer-Reviewed Original ResearchConceptsShortness of breathPredictors of severityTaste dysfunctionNeurological manifestationsNeurological symptomsSevere casesCOVID-19Multicenter prospective clinical studyMulti-center prospective studyHyposmia/anosmiaGuillain-Barré syndromeWeeks of dischargeProspective clinical studyCommon neurological symptomsTime of admissionNon-neurological manifestationsCoronavirus disease 2019COVID-19 diseaseCerebrovascular eventsChest tightnessStatus epilepticusEligible casesNeurological findingsProspective studyMild headacheCommentary on 2 Cases of Neuropsychiatric Symptoms Occurring in Association With COVID-19
Garakani A. Commentary on 2 Cases of Neuropsychiatric Symptoms Occurring in Association With COVID-19. Journal Of Psychiatric Practice 2021, 27: 145-146. PMID: 33656822, DOI: 10.1097/pra.0000000000000527.Commentaries, Editorials and LettersConceptsPositive COVID-19 testCOVID-19 infectionNeuropsychiatric symptomsPsychotic symptomsSuicide attemptsCoronavirus disease 2019 (COVID-19) infectionCOVID-19Recent respiratory illnessDisease 2019 infectionAcute psychotic symptomsHistory of depressionInpatient psychiatric unitMiddle-age menSerious suicide attemptsCOVID-19 testPatient's symptomsNeuropsychiatric sequelaeRespiratory illnessAntipsychotic medicationPatient's psychosisPsychotic episodeMood symptomsNeurological etiologyPsychiatric historyPsychiatric unit
2020
Sublingual Oxytocin With Clozapine in a Patient With Persisting Psychotic Symptoms, Suicidal Thinking With Self-Harm.
Garakani A, Buono FD, Marotta RF. Sublingual Oxytocin With Clozapine in a Patient With Persisting Psychotic Symptoms, Suicidal Thinking With Self-Harm. Journal Of Clinical Psychopharmacology 2020, 40: 507-509. PMID: 32701906, DOI: 10.1097/jcp.0000000000001248.Peer-Reviewed Case Reports and Technical NotesGaming and Gaming Disorder: A Mediation Model Gender, Salience, Age of Gaming Onset, and Time Spent Gaming
Buono FD, Paul E, Sprong ME, Smith EC, Garakani A, Griffiths MD. Gaming and Gaming Disorder: A Mediation Model Gender, Salience, Age of Gaming Onset, and Time Spent Gaming. Cyberpsychology Behavior And Social Networking 2020, 23: 647-651. PMID: 32654509, DOI: 10.1089/cyber.2019.0445.Peer-Reviewed Original ResearchThe effects of augmenting clozapine with oxytocin in schizophrenia: An initial case series.
Marotta RF, Buono FD, Garakani A, Collins E, Cerrito B, David Rowe DR. The effects of augmenting clozapine with oxytocin in schizophrenia: An initial case series. Annals Of Clinical Psychiatry 2020, 32: 90-96. PMID: 32343282.Peer-Reviewed Case Reports and Technical NotesConceptsTreatment-resistant schizophreniaNegative symptomsAtypical antipsychoticsRetrospective chart reviewInitial case seriesAugmentation of clozapineChronic psychotic illnessNegative Syndrome ScaleYoung adult inpatientsSymptoms of schizophreniaParent/guardian reportsChart reviewCase seriesAdult inpatientsProspective studyAntipsychotic medicationClinical reviewTherapeutic responsePsychotic illnessTreatment approachesSyndrome ScalePositive symptomsTreating psychiatristSymptomsSustained treatmentParsing the effects of comorbid adult ADHD and substance misuse on affective lability in bipolar disorder
Garakani A, Buono FD, Larkin K, Goldberg JF. Parsing the effects of comorbid adult ADHD and substance misuse on affective lability in bipolar disorder. Journal Of Affective Disorders 2020, 266: 338-340. PMID: 32056896, DOI: 10.1016/j.jad.2020.01.087.Peer-Reviewed Original ResearchConceptsAffective labilityAdult ADHDSubstance misuseSubstance use disorder inpatientsDisorder inpatientsMost subscale scoresInpatient treatment programAttentional deficitsCurrent substance misuseADHD ratingsADHD scoresComorbid ADHDADHD screenSignificant partial correlationsADHD comorbidityBipolar disorderBipolar disorder inpatientsBipolar subjectsADHDSemi-structured interviewsMultiple domainsTreatment programSingle private institutionSubscale scoresStandardized scales
2019
Pharmacogenomic Testing in Psychiatry: Ready for Primetime?
Rakesh G, Sumner CR, Alexander JL, Gross LS, Pine J, Slaby A, Garakani A, Baron D. Pharmacogenomic Testing in Psychiatry: Ready for Primetime? The Journal Of Nervous And Mental Disease 2019, 208: 127-130. PMID: 31895226, DOI: 10.1097/nmd.0000000000001107.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsRetrospective Chart Review of Voluntary Admissions to an Inpatient Psychiatric Hospital in New York City: A Demographic Breakdown
Garakani A, Cerrito B, Aloysi A, Martinez J, Buono FD. Retrospective Chart Review of Voluntary Admissions to an Inpatient Psychiatric Hospital in New York City: A Demographic Breakdown. Community Mental Health Journal 2019, 56: 448-455. PMID: 31654251, DOI: 10.1007/s10597-019-00498-2.Peer-Reviewed Original ResearchPatient Requests for Discharge from Voluntary Psychiatric Hospitalization: a Chart Review
Garakani A, Appel JM, Aloysi AS, Martinez JM, Larkin K, Buono FD. Patient Requests for Discharge from Voluntary Psychiatric Hospitalization: a Chart Review. Psychiatric Quarterly 2019, 90: 849-859. PMID: 31468251, DOI: 10.1007/s11126-019-09671-y.Peer-Reviewed Original ResearchConceptsPsychiatric hospitalizationAdmission dayUrine toxicologyVoluntary Psychiatric HospitalizationSuicidal ideationNew York City hospitalsPositive urine toxicologyPrevious psychiatric hospitalizationInpatient psychiatric admissionStepwise linear regression analysisCalendar year 2007Chart reviewEarly dischargePsychiatric admissionsPatient outcomesInpatient careTobacco useCity HospitalPatient's requestInpatient servicesLinear regression analysisCigarette usePsychiatric inpatientsVoluntary admissionHospitalization
2017
Opinions Regarding Benzodiazepine Teaching and Prescribing Among Trainees in Psychiatry
Garakani A, Abdullah HM, Chang CM, Mendelsohn N, Lapidus KAB. Opinions Regarding Benzodiazepine Teaching and Prescribing Among Trainees in Psychiatry. Academic Psychiatry 2017, 42: 297-303. PMID: 28685349, DOI: 10.1007/s40596-017-0750-0.Peer-Reviewed Original Research
2015
Heart rate and respiratory response to doxapram in patients with panic disorder
Martinez JM, Garakani A, Aaronson CJ, Gorman JM. Heart rate and respiratory response to doxapram in patients with panic disorder. Psychiatry Research 2015, 227: 32-38. PMID: 25819170, PMCID: PMC4420657, DOI: 10.1016/j.psychres.2015.03.001.Peer-Reviewed Original ResearchConceptsPD patientsLF/HFPanic disorderHealthy controlsAnticipatory anxietyPD subjectsParasympathetic componentRespiratory responsesLF/HF ratioSensation of dyspneaHeart rate variability indicesHigher sympathetic activityInjection of salinePanic statesSympathetic activityRespiratory abnormalitiesBrain stemRespiratory stimulantHeart rateParasympathetic responsePanic attacksPatientsExaggerated fear responsePanic symptomsHF ratio
2013
Electroconvulsive Therapy (ECT) for Catatonia in a Patient With Schizophrenia and Synthetic Cannabinoid Abuse
Leibu E, Garakani A, McGonigle DP, Liebman LS, Loh D, Bryson EO, Kellner CH. Electroconvulsive Therapy (ECT) for Catatonia in a Patient With Schizophrenia and Synthetic Cannabinoid Abuse. Journal Of Ect 2013, 29: e61-e62. PMID: 23670023, DOI: 10.1097/yct.0b013e318290fa36.Peer-Reviewed Case Reports and Technical NotesTransient Febrile Reaction After Electroconvulsive Therapy (ECT) in a Young Adult With Intellectual Disability and Bipolar Disorder
Majeske MF, Garakani A, Maloutas E, Bryson EO, Kellner CH. Transient Febrile Reaction After Electroconvulsive Therapy (ECT) in a Young Adult With Intellectual Disability and Bipolar Disorder. Journal Of Ect 2013, 29: e63-e65. PMID: 23774055, DOI: 10.1097/yct.0b013e3182972b8c.Peer-Reviewed Case Reports and Technical NotesConceptsElectroconvulsive therapyECT treatmentManic symptomsIntellectual disabilityBipolar disorderUse of ECTAdditional ECT treatmentsMultiple medication trialsTransient febrile reactionMild-moderate intellectual disabilityFever workupTransient feverMedication trialsFebrile reactionsPressured speechManic statePatient's motherPsychiatric disordersPatientsYoung adultsDisordersFeverTreatmentTherapySymptoms
2012
Clinician-rated versus self-rated screening for bipolar disorder among inpatients with mood symptoms and substance misuse.
Goldberg JF, Garakani A, Ackerman SH. Clinician-rated versus self-rated screening for bipolar disorder among inpatients with mood symptoms and substance misuse. The Journal Of Clinical Psychiatry 2012, 73: 1525-30. PMID: 23290325, DOI: 10.4088/jcp.12m07926.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultAgedAlcoholismBipolar DisorderCross-Sectional StudiesDiagnosis, Dual (Psychiatry)Diagnostic Self EvaluationFemaleHospitalizationHumansInterview, PsychologicalMaleMass ScreeningMiddle AgedObserver VariationPsychometricsReproducibility of ResultsSubstance-Related DisordersYoung AdultConceptsMood Disorder QuestionnaireBipolar disorderSubstance misusePredictive valueHigh negative predictive valuePatient-clinician concordanceLow positive predictive valueDSM-IV-TR criteriaMood disorder patientsHigh prevalence ratesCross-sectional assessmentCurrent substance misuseSubstance use disordersNegative predictive valuePositive predictive valueSubstance use symptomsPsychiatrist's reviewClinician interviewsPositive statusMood disordersPrevalence ratesMood symptomsLifetime substanceUse disordersBipolar diagnosisCerebrospinal fluid levels of glutamate and corticotropin releasing hormone in major depression before and after treatment
Garakani A, Martinez JM, Yehuda R, Gorman JM. Cerebrospinal fluid levels of glutamate and corticotropin releasing hormone in major depression before and after treatment. Journal Of Affective Disorders 2012, 146: 262-265. PMID: 22840611, DOI: 10.1016/j.jad.2012.06.037.Peer-Reviewed Original Research
2011
PROINFLAMMATORY AND “RESILIENCY” PROTEINS IN THE CSF OF PATIENTS WITH MAJOR DEPRESSION
Martinez JM, Garakani A, Yehuda R, Gorman JM. PROINFLAMMATORY AND “RESILIENCY” PROTEINS IN THE CSF OF PATIENTS WITH MAJOR DEPRESSION. Depression And Anxiety 2011, 29: 32-38. PMID: 21898706, DOI: 10.1002/da.20876.Peer-Reviewed Original ResearchMeSH KeywordsAdultAntidepressive Agents, Second-GenerationBrain-Derived Neurotrophic FactorCyclohexanolsDepressive Disorder, MajorFemaleHumansInflammationInflammation MediatorsInterleukin-1Interleukin-6MaleMiddle AgedNeuropeptide YSeverity of Illness IndexTumor Necrosis Factor-alphaUp-RegulationVenlafaxine HydrochlorideConceptsInflammatory cytokinesDepressed patientsHealthy controlsMajor depressionCSF cytokine levelsCSF of patientsCerebrospinal fluid levelsLumbar puncture procedureNormal comparison groupInflammatory hypothesisNPY concentrationsNPY levelsCytokine levelsIL-6Lumbar punctureClinical severityTreatment protocolIL-1CSF samplesPatientsNeuroprotective peptideFluid levelsSuicidal ideationPuncture procedureSmall sample size