2024
Vitamin B12 Supplementation in Psychiatric Practice
Kennedy K, Alexander J, Garakani A, Gross L, Mintz D, Parikh T, Pine J, Sumner C, Baron D. Vitamin B12 Supplementation in Psychiatric Practice. Current Psychiatry Reports 2024, 26: 265-272. PMID: 38696105, DOI: 10.1007/s11920-024-01505-4.Peer-Reviewed Original ResearchPsychiatric disordersB12 deficiencyB12 supplementationPsychiatric symptomsB12 levelsPharmacological treatment of psychiatric disordersTreatment of psychiatric disordersRisk factorsAssociated with neuropsychiatric symptomsSevere psychiatric presentationsManifestations of B12 deficiencyMild depressive symptomsVitamin B12 supplementationDepressive symptomsPsychiatric practicePsychiatric presentationsMedical workupNeuropsychiatric symptomsSymptoms of B12 deficiencyAugmentation strategiesPrevent depressionPharmacological treatmentCardinal symptomsDisordersSymptoms
2021
Intensive Dialectical Behavior Treatment for Individuals With Borderline Personality Disorder With and Without Substance Use Disorders
Buono FD, Larkin K, Rowe D, Perez-Rodriguez MM, Sprong ME, Garakani A. Intensive Dialectical Behavior Treatment for Individuals With Borderline Personality Disorder With and Without Substance Use Disorders. Frontiers In Psychology 2021, 12: 629842. PMID: 34497550, PMCID: PMC8419465, DOI: 10.3389/fpsyg.2021.629842.Peer-Reviewed Original ResearchSubstance use disordersBorderline personality disorderComorbid substance use disorderUse disordersDialectical behavioral therapyTreatment programComorbid borderline personality disorderPersonality disorderDepression symptom scaleModerate depression scoresDepressive symptomsGroup 2Depression scoresGroup 1Symptom ScaleDBT treatmentSymptom overlapUnivariate general linear modelBehavioral therapyDisordersSignificant decreaseBehavior treatmentGeneral linear modelSignificant differencesPatientsCommentary: Diagnostic Challenges in Evaluating Adolescents
Garakani A. Commentary: Diagnostic Challenges in Evaluating Adolescents. Journal Of Psychiatric Practice 2021, 27: 239-240. PMID: 33939380, DOI: 10.1097/pra.0000000000000553.Commentaries, Editorials and LettersConceptsDiagnostic challengeConstellation of symptomsProminent mood symptomsPosttraumatic stress disorderFemale patientsTrauma-related symptomsMedication treatmentAntipsychotic medicationAdolescent patientsUnnecessary treatmentVisual hallucinationsDifferential diagnosisPatient reportsTerms of stigmaMood symptomsDepressive symptomsPsychotic symptomsSide effectsPatientsPsychotic disordersSuicidal ideasFull differential diagnosisAuditory hallucinationsCotard's syndromeIncorrect diagnosis
2020
Impact of depressive symptoms on self-perceived severity of autonomic dysfunction in multiple system atrophy: relevance for patient-reported outcomes in clinical trials
Martinez J, Palma JA, Norcliffe-Kaufmann L, Garakani A, Kaufmann H. Impact of depressive symptoms on self-perceived severity of autonomic dysfunction in multiple system atrophy: relevance for patient-reported outcomes in clinical trials. Clinical Autonomic Research 2020, 30: 215-221. PMID: 32246226, PMCID: PMC7341538, DOI: 10.1007/s10286-020-00681-6.Peer-Reviewed Original ResearchConceptsMultiple system atrophyOrthostatic Hypotension QuestionnaireSymptoms of depressionOrthostatic hypotensionAutonomic dysfunctionDepressive symptomsSelf-perceived severityAutonomic symptomsSystem atrophyDepression scoresOHQ scoresOrthostatic blood pressure fallUnified MSA Rating ScaleProbable multiple system atrophyComposite Autonomic Symptom ScoreBlood pressure fallResultsFifty-eight patientsSystolic blood pressureZung depression scorePatient-reported outcomesAutonomic symptom scoreClinical trial designMultivariable regression modelsQuality of lifeConclusionsIn patients
2015
New‐Onset Panic, Depression with Suicidal Thoughts, and Somatic Symptoms in a Patient with a History of Lyme Disease
Garakani A, Mitton AG. New‐Onset Panic, Depression with Suicidal Thoughts, and Somatic Symptoms in a Patient with a History of Lyme Disease. Case Reports In Psychiatry 2015, 2015: 457947. PMID: 25922779, PMCID: PMC4397473, DOI: 10.1155/2015/457947.Peer-Reviewed Case Reports and Technical NotesChronic Lyme diseasePanic attacksLyme diseaseDepressive symptomsPhysical symptomsLong-term antibioticsSevere depressive symptomsInpatient psychiatric hospitalizationSubsyndromal depressive symptomsComorbid psychiatric diagnosesChronic physical symptomsBack spasmsLyme titersNeuromuscular complaintsCLD patientsNeuropathic painJoint painTick bitePsychiatric hospitalizationAnxiolytic treatmentPsychiatric symptomsPsychiatric historyPsychiatric diagnosisNeurological disordersSuicidal ideation