2016
Biotransformation and Rearrangement of Laromustine
Nassar AE, Wisnewski AV, King I. Biotransformation and Rearrangement of Laromustine. Drug Metabolism And Disposition 2016, 44: 1349-1363. PMID: 27278961, DOI: 10.1124/dmd.116.069823.Peer-Reviewed Original ResearchConceptsNuclear magnetic resonance spectroscopyCollision-induced dissociationFourier transform ion cyclotron resonance mass spectrometerIon cyclotron resonance mass spectrometerAccurate mass measurementsMass spectrometry studiesHydrogen-deuterium exchangeMagnetic resonance spectroscopyMass spectral rearrangementsExact massSpectrometry studiesEnzyme catalysisReactive intermediatesMass spectrometerDecomposition productsResonance spectroscopyConjugation reactionsElemental compositionPossibility of rearrangementMass measurementsSpectral rearrangementsDissociationRadioactive componentsLoss of nitrogenMetabolite products
2006
Suburban Leptospirosis: Atypical Lymphocytosis and γ-δ T Cell Response
Barry M, Wisnewski AV, Matthias MA, Inouye SK, Vinetz JM. Suburban Leptospirosis: Atypical Lymphocytosis and γ-δ T Cell Response. Clinical Infectious Diseases 2006, 43: 1304-1307. PMID: 17051497, DOI: 10.1086/508537.Peer-Reviewed Original ResearchConceptsAtypical lymphocytosisGamma delta T cellsT cell responsesCases of leptospirosisRate of infectionPeripheral bloodT cellsGlobal epidemiologyCell responsesCanine leptospirosisLeptospirosisZoonotic diseaseLymphocytosisSuburban settingsEpidemiologyReservoir hostsDiseasePathogenesisInfectionIncidenceSettingDiagnosisBlood