2024
Atopic dermatitis in women: special considerations in the childbearing years
Valentini R, Shahriari M. Atopic dermatitis in women: special considerations in the childbearing years. International Journal Of Women's Dermatology 2024, 10: e151. PMID: 38860232, PMCID: PMC11164005, DOI: 10.1097/jw9.0000000000000151.Peer-Reviewed Original ResearchWomen of childbearing ageAtopic dermatitisChildbearing ageTreating women of childbearing ageReview special considerationsRandomized controlled trialsSystemic therapyTopical therapyGoogle Scholar databasesRecommended therapyInflammatory dermatosesUncontrolled ADLactating womenTreated womenPotential therapiesChildbearing yearsTherapyControlled trialsGold standardQuality of lifeUnborn babyDatabase inceptionRelevant articlesOptimal careOptimal outcomesUpadacitinib for the treatment of psoriasiform and spongiotic dermatitis: A multicenter case series
Shahriari N, Strober B, Shahriari M. Upadacitinib for the treatment of psoriasiform and spongiotic dermatitis: A multicenter case series. JAAD Case Reports 2024, 49: 106-109. PMID: 38952860, PMCID: PMC11214991, DOI: 10.1016/j.jdcr.2024.05.009.Peer-Reviewed Original ResearchLebrikizumab Provides Rapid Clinical Responses Across All Eczema Area and Severity Index Body Regions and Clinical Signs in Adolescents and Adults with Moderate-to-Severe Atopic Dermatitis
Simpson E, de Bruin-Weller M, Hong H, Staumont-Sallé D, Blauvelt A, Eyerich K, Gooderham M, Shahriari M, Mallbris L, Atwater A, Rueda M, Ding Y, Liu Z, Agell H, Silverberg J. Lebrikizumab Provides Rapid Clinical Responses Across All Eczema Area and Severity Index Body Regions and Clinical Signs in Adolescents and Adults with Moderate-to-Severe Atopic Dermatitis. Dermatology And Therapy 2024, 14: 1145-1160. PMID: 38700646, PMCID: PMC11116327, DOI: 10.1007/s13555-024-01158-4.Peer-Reviewed Original ResearchEczema Area and Severity IndexWeek 2Clinical signsHead and neck regionRefractory to treatmentBody regionsSeverity of ADClinical responseEczema AreaEfficacy measuresPlaceboAtopic dermatitisLebrikizumabNeck regionIntroductionAtopic dermatitisMonotherapyWeeksPost-hocErythemaPatientsSeveritySeverity IndexEczemaDermatitisLichenification533 - Long-term 5-year safety of upadacitinib in moderate-to-severe atopic dermatitis: an integrated analysis including over 7000 patient-years of exposure
Bunick C, Chovatiya R, Guttman E, Shahriari M, Boguniewicz M, Gao X, Greiwe J, Blauvelt A, Schuttelaar M, Irvine A, Levy G, Platt A, Dilley D, Teixeira H, Altman K, Grada A, Silverberg J. 533 - Long-term 5-year safety of upadacitinib in moderate-to-severe atopic dermatitis: an integrated analysis including over 7000 patient-years of exposure. British Journal Of Dermatology 2024, 190: ii35-ii36. DOI: 10.1093/bjd/ljad498.037.Peer-Reviewed Original ResearchNon-melanoma skin cancerMajor adverse cardiovascular eventsVenous thromboembolic eventsAtopic dermatitisAdverse eventsAdjudicated major adverse cardiovascular eventsOral Janus kinase 1Rate of serious infectionTreatment-emergent adverse eventsLong-term safety dataDuration of follow-upConcomitant topical corticosteroidsEfficacy of upadacitinibDouble-blind periodRate of adverse eventsPhase 3 studyDoses of upadacitinibEczematous skin lesionsExposure-adjusted ratesMATERIALS & METHODSYear of treatmentAdverse cardiovascular eventsBenefit-risk profileInflammatory skin diseaseLong-term safetyA retrospective multicenter case series of real-world tralokinumab use in dupilumab-experienced patients
Herman E, Burgy J, Shahriari M. A retrospective multicenter case series of real-world tralokinumab use in dupilumab-experienced patients. JAAD Case Reports 2024, 46: 40-44. PMID: 38510837, PMCID: PMC10950487, DOI: 10.1016/j.jdcr.2024.01.021.Peer-Reviewed Original ResearchReal-World Tralokinumab Use in Dupilumab-Experienced Patients: A Eetrospective Multi-Center Case Series
Herman E, Burgy J, Shahriari M. Real-World Tralokinumab Use in Dupilumab-Experienced Patients: A Eetrospective Multi-Center Case Series. SKIN The Journal Of Cutaneous Medicine 2024, 8: s321. DOI: 10.25251/skin.8.supp.321.Peer-Reviewed Original ResearchTreated with dupilumabAtopic dermatitisDupilumab treatmentTralokinumab treatmentCase seriesSafety profileLong-term disease controlHead-to-head studiesDiscontinued dupilumab treatmentTreated with topicalMulti-center case seriesDuration of treatmentLack of efficacyEvaluate clinical findingsBiologic dupilumabHerpes labialisNRS scoresAdult patientsClinical findingsDupilumabTreatment optionsEffective therapyTralokinumabDisease durationJoint pain
2023
Lebrikizumab Provides Rapid Response in EASI Components and Itch in Moderate-to-Severe Atopic Dermatitis
Simpson E, Yosipovitch G, Eyerich K, Staumont-Sallé D, Shahriari M, Gallo G, Wolf E, Pierce E, Liu C, Zhong J, Agell H, De Bruin-Weller M. Lebrikizumab Provides Rapid Response in EASI Components and Itch in Moderate-to-Severe Atopic Dermatitis. SKIN The Journal Of Cutaneous Medicine 2023, 7: s279. DOI: 10.25251/skin.7.supp.279.Peer-Reviewed Original Research