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  • Assistant Professor of Neurology; Affiliated Faculty, Yale Institute of Global Health; Stroke Director, U.S. Department of Veterans Affairs

    Nishant K. Mishra, MD, PhD, FRCP, FESO, FAHA is a stroke neurologist. His journey in stroke medicine started in 2005 when he found Praful M Dalal, MD, and Shirish M Hastak, MD, as his mentors in Mumbai, who introduced him to the art of clinical neurology, particularly vascular neurology. Dr. Dalal would tell him how he extracted tissue plasminogen activator from blood during his time at Oxford, studied the vascular anatomy by injecting dyes in the human brain, and how his approach was shaped working with his mentor Miller Fisher a long time ago. Young, enthusiastic, and focused, Dr. Mishra began looking for opportunities and went to Lausanne, known for the Lausanne Stroke Registry, in 2006. The Swiss Government fully funded this, and he learned clinical stroke and behavioral neurology under the mentorship of Antonio Carota, MD, Jean Marie Annoni, and many others. Dr. Mishra was selected by Kennedy Lees, MD, at Glasgow, where he was fully funded to conduct his clinical research at the Western Infirmary Hospital, Glasgow. He was fully supported by the University of Glasgow and the Scottish Government’s ORS funding. Through this, Dr. Mishra successfully defended a PhD thesis on using thrombolytic therapy beyond recommendations in acute ischemic stroke. Subsequently, Dr. Greg Albers recruited him to Stanford, where he closely worked with experts like Maarten Lansberg, MD, PhD, and Soren Christensen, PhD, to develop expertise in perfusion image-based stroke outcome prognostication. Subsequently, Dr. Mishra spent a year at the US Food and Drug Administration Center for Devices and Radiological Health, investigating sex differences in outcomes using TAVR devices. Then, he spent five years doing a US ACGME residency (two years at Tulane, two years at Icahn School of Mount Sinai, and one year at UCLA) before moving to Yale. Dr. Mishra has come to Yale with the following mission: (1) service through excellent clinical care; (2) build an extensive collaborative research program to promote stroke outcomes, e.g. IPSERC; (3) support the younger generation (trainees, junior faculties) in succeeding with their vision and making a meaningful contribution to society. Dr. Mishra is the Stroke Director at the Veteran Affairs Medical Center, West Haven, CT. He enjoys serving the veterans and making a meaningful contribution to their lives.
  • Postdoctoral Associate

    Dr. Misra is a Postdoctoral Associate in the Department of Neurology at Yale University School of Medicine. He is a clinical researcher with an avid interest in biomarker discovery and outcomes research in neurological disorders. He is serving as a member of the COVID-19 global forum in the Brain Health Unit of the World Health Organization. He is also the Guest Editor at Frontiers in Neurology, where he is leading a research collection on omics-based approaches in stroke research. His long-term goal is to become an independent investigator and build a career in clinical biomarker discovery and data sciences. Dr. Misra obtained his Ph.D. in Neurology from the All India Institute of Medical Sciences, New Delhi, India. His thesis was aimed at determining diagnostic and prognostic biomarkers of stroke using high-throughput proteomics and machine learning approaches. He received the prestigious DST-INSPIRE Fellowship from the Department of Science and Technology, Government of India, for pursuing his doctoral studies. He completed his B. Tech and M. Tech degrees in Biotechnology from Amity University, Noida, India, and had the distinction of being the University Gold Medalist. Dr. Misra has co-authored over 50 peer-reviewed research publications, including first-author articles in leading journals such as JAMA Neurology, Neurology, the European Journal of Neurology, and the International Journal of Stroke. His work has been cited more than 1,000 times. He took a 2-hour lecture on "Proteomics data analysis in R" at the peer-to-peer teaching sessions organized by the Bioinformatics Support Hub in the Cushing/Whitney Medical Library at Yale School of Medicine. Dr. Misra is a recipient of the Young Investigator Award from the World Stroke Organization for his contributions to the field of stroke research. He is open to research collaborations on research topics, including: Biomarker research in stroke Proteomics data analysis Evidence synthesis through systematic reviews and meta-analyses Clinical trials in stroke For research collaborations, reach out to Dr. Misra at shubham.misra@yale.edu. For more details regarding his academic interests, please visit his website at https://sites.google.com/view/shubham-misra.

Trainess/Students

Alumni

  • Erum I. Khan, MBBS is currently a post-doctoral fellow at the Alzheimer’s Disease Research Center at the University of Alabama. She served in the Mishra Lab as a visiting medical student and has continued to work on collaborative projects. She aims to complete residency training in neurology and become a physician-scientist.
  • Ece Eldem, MSc (Universite de Fribourg, Switzerland) served as a postgraduate trainee in the Mishra Lab and plans pursue research in clinical neurology.