Publications

2025

Nuclear mechanics as a determinant of nuclear pore complex plasticity
Lusk C, Morgan K, King M. Nuclear mechanics as a determinant of nuclear pore complex plasticity. Nature Cell Biology 2025, 27: 1622-1631. PMID: 40973737, DOI: 10.1038/s41556-025-01768-w.
Peer-Reviewed Original Research
Concepts
Sense, plug, and seal: proteins as both rapid responders and constitutive barriers supporting organelle compartmentalization.
King M, Lusk C, Ader N. Sense, plug, and seal: proteins as both rapid responders and constitutive barriers supporting organelle compartmentalization. Molecular Biology Of The Cell 2025, 36: pe6. PMID: 40601416, PMCID: PMC12367315, DOI: 10.1091/mbc.e23-08-0307.
Peer-Reviewed Original Research
MeSH Keywords and Concepts
Visualizing nuclear pore complex plasticity with pan-expansion microscopy
Morgan K, Carley E, Coyne A, Rothstein J, Lusk C, King M. Visualizing nuclear pore complex plasticity with pan-expansion microscopy. Journal Of Cell Biology 2025, 224: e202409120. PMID: 40504117, PMCID: PMC12162248, DOI: 10.1083/jcb.202409120.
Peer-Reviewed Original Research
MeSH Keywords and Concepts
Coarse-grained chromatin dynamics by tracking multiple similarly labeled gene loci
Mader A, Rodriguez A, Yuan T, Surovtsev I, King M, Mochrie S. Coarse-grained chromatin dynamics by tracking multiple similarly labeled gene loci. Biophysical Journal 2025, 124: 2120-2132. PMID: 40369871, PMCID: PMC12256843, DOI: 10.1016/j.bpj.2025.05.008.
Peer-Reviewed Original Research
Concepts
A quantitative ultrastructural timeline of nuclear autophagy reveals a role for dynamin-like protein 1 at the nuclear envelope
Mannino P, Perun A, Surovtsev I, Ader N, Shao L, Rodriguez E, Melia T, King M, Lusk C. A quantitative ultrastructural timeline of nuclear autophagy reveals a role for dynamin-like protein 1 at the nuclear envelope. Nature Cell Biology 2025, 27: 464-476. PMID: 39920277, PMCID: PMC11908896, DOI: 10.1038/s41556-025-01612-1.
Peer-Reviewed Original Research
MeSH Keywords and Concepts
Nup107 contributes to the maternal-to-zygotic transition by preventing the premature nuclear export of pri-miR427
Kostiuk V, Kabir R, Levangie K, Empke S, Morgan K, Owens N, Lusk C, Khokha M. Nup107 contributes to the maternal-to-zygotic transition by preventing the premature nuclear export of pri-miR427. Development 2025, 152: dev202865. PMID: 39791357, PMCID: PMC11829755, DOI: 10.1242/dev.202865.
Peer-Reviewed Original Research
MeSH Keywords and Concepts

2024

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Publications

2025

Nuclear mechanics as a determinant of nuclear pore complex plasticity

Sense, plug, and seal: proteins as both rapid responders and constitutive barriers supporting organelle compartmentalization.

Visualizing nuclear pore complex plasticity with pan-expansion microscopy

Coarse-grained chromatin dynamics by tracking multiple similarly labeled gene loci

A quantitative ultrastructural timeline of nuclear autophagy reveals a role for dynamin-like protein 1 at the nuclear envelope

Nup107 contributes to the maternal-to-zygotic transition by preventing the premature nuclear export of pri-miR427

2024

Cohesin distribution alone predicts chromatin organization in yeast via conserved-current loop extrusion

Channel width modulates the permeability of DNA origami–based nuclear pore mimics

A-tisket, a-tasket, what a beautiful nuclear basket

Identifying topologically associating domains using differential kernels

The condensation of HP1α/Swi6 imparts nuclear stiffness

The multidimensional roles of intermediate filaments - bridging genetic diversity with form, functions, and targets

Effect of loops on the mean-square displacement of Rouse-model chromatin

2023

It is time to reconsider the culture of volunteerism in undergraduate research

Dynamic regulation of LINC complex composition and function across tissues and contexts

An ESCRT grommet cooperates with a diffusion barrier to maintain nuclear integrity

Changing the guard—nuclear pore complex quality control

Acetyl-methyllysine marks chromatin at active transcription start sites

Elasticity of spheres with buckled surfaces

Loops and the activity of loop extrusion factors constrain chromatin dynamics

The capsid lattice engages a bipartite NUP153 motif to mediate nuclear entry of HIV-1 cores

Modeling HIV-1 nuclear entry with nucleoporin-gated DNA-origami channels

2022

Functionalized DNA-Origami-Protein Nanopores Generate Large Transmembrane Channels with Programmable Size-Selectivity

Kap-β2/Transportin mediates β-catenin nuclear transport in Wnt signaling

Quality control mechanisms that protect nuclear envelope identity and function