Publications

2026

Integration of nuclear mechanosensing with integrin-extracellular matrix adhesions
Sandria S, King M. Integration of nuclear mechanosensing with integrin-extracellular matrix adhesions. Nucleus 2026, 17: 2677308. PMID: 42209418, PMCID: PMC13220845, DOI: 10.1080/19491034.2026.2677308.
Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus Statements
MeSH Keywords
Loss of JAK1 Function Causes G2/M Cell Cycle Defects Vulnerable to KIF18A Inhibition
Kelley V, Baro M, Gasperi W, Ader N, Lea H, Lee H, Phoomak C, Kabeche L, King M, Contessa J. Loss of JAK1 Function Causes G2/M Cell Cycle Defects Vulnerable to KIF18A Inhibition. Cancer Research 2026, 86: 2301-2317. PMID: 41591363, PMCID: PMC13107398, DOI: 10.1158/0008-5472.can-25-1423.
Peer-Reviewed Original Research

2025

The LINC complex component Kms1 and CENP-B protein Cbp1 cooperate to enforce faithful homology-directed DNA repair at the nuclear periphery in S. pombe
Laffitte A, Lin D, Tian Y, Liu N, Lusk C, Mochrie S, King M. The LINC complex component Kms1 and CENP-B protein Cbp1 cooperate to enforce faithful homology-directed DNA repair at the nuclear periphery in S. pombe. Genes & Development 2025, 40: 456-474. PMID: 41436280, PMCID: PMC13041547, DOI: 10.1101/gad.353167.125.
Peer-Reviewed Original Research
Nuclear mechanics as a determinant of nuclear pore complex plasticity
Lusk C, Morgan K, King M. Nuclear mechanics as a determinant of nuclear pore complex plasticity. Nature Cell Biology 2025, 27: 1622-1631. PMID: 40973737, DOI: 10.1038/s41556-025-01768-w.
Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus Statements
Sense, plug, and seal: proteins as both rapid responders and constitutive barriers supporting organelle compartmentalization.
King M, Lusk C, Ader N. Sense, plug, and seal: proteins as both rapid responders and constitutive barriers supporting organelle compartmentalization. Molecular Biology Of The Cell 2025, 36: pe6. PMID: 40601416, PMCID: PMC12367315, DOI: 10.1091/mbc.e23-08-0307.
Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus Statements
MeSH Keywords
Visualizing nuclear pore complex plasticity with pan-expansion microscopy
Morgan K, Carley E, Coyne A, Rothstein J, Lusk C, King M. Visualizing nuclear pore complex plasticity with pan-expansion microscopy. Journal Of Cell Biology 2025, 224: e202409120. PMID: 40504117, PMCID: PMC12162248, DOI: 10.1083/jcb.202409120.
Peer-Reviewed Original Research
MeSH Keywords
Coarse-grained chromatin dynamics by tracking multiple similarly labeled gene loci
Mader A, Rodriguez A, Yuan T, Surovtsev I, King M, Mochrie S. Coarse-grained chromatin dynamics by tracking multiple similarly labeled gene loci. Biophysical Journal 2025, 124: 2120-2132. PMID: 40369871, PMCID: PMC12256843, DOI: 10.1016/j.bpj.2025.05.008.
Peer-Reviewed Original Research
A quantitative ultrastructural timeline of nuclear autophagy reveals a role for dynamin-like protein 1 at the nuclear envelope
Mannino P, Perun A, Surovtsev I, Ader N, Shao L, Rodriguez E, Melia T, King M, Lusk C. A quantitative ultrastructural timeline of nuclear autophagy reveals a role for dynamin-like protein 1 at the nuclear envelope. Nature Cell Biology 2025, 27: 464-476. PMID: 39920277, PMCID: PMC11908896, DOI: 10.1038/s41556-025-01612-1.
Peer-Reviewed Original Research
MeSH Keywords
Nup107 contributes to the maternal-to-zygotic transition by preventing the premature nuclear export of pri-miR427
Kostiuk V, Kabir R, Levangie K, Empke S, Morgan K, Owens N, Lusk C, Khokha M. Nup107 contributes to the maternal-to-zygotic transition by preventing the premature nuclear export of pri-miR427. Development 2025, 152: dev202865. PMID: 39791357, PMCID: PMC11829755, DOI: 10.1242/dev.202865.
Peer-Reviewed Original Research
MeSH Keywords

2024

Cohesin distribution alone predicts chromatin organization in yeast via conserved-current loop extrusion
Yuan T, Yan H, Li K, Surovtsev I, King M, Mochrie S. Cohesin distribution alone predicts chromatin organization in yeast via conserved-current loop extrusion. Genome Biology 2024, 25: 293. PMID: 39543681, PMCID: PMC11566905, DOI: 10.1186/s13059-024-03432-2.
Peer-Reviewed Original Research
MeSH Keywords
Channel width modulates the permeability of DNA origami–based nuclear pore mimics
Feng Q, Saladin M, Wu C, Cao E, Zheng W, Zhang A, Bhardwaj P, Li X, Shen Q, Kapinos L, Kozai T, Mariappan M, Lusk C, Xiong Y, Lim R, Lin C. Channel width modulates the permeability of DNA origami–based nuclear pore mimics. Science Advances 2024, 10: eadq8773. PMID: 39536094, PMCID: PMC11559598, DOI: 10.1126/sciadv.adq8773.
Peer-Reviewed Original Research
MeSH Keywords
A-tisket, a-tasket, what a beautiful nuclear basket
Lusk C, King M. A-tisket, a-tasket, what a beautiful nuclear basket. Cell 2024, 187: 5225-5227. PMID: 39303690, DOI: 10.1016/j.cell.2024.08.030.
Peer-Reviewed Original Research
MeSH Keywords
Identifying topologically associating domains using differential kernels
Maisuradze L, King M, Surovtsev I, Mochrie S, Shattuck M, O’Hern C. Identifying topologically associating domains using differential kernels. PLOS Computational Biology 2024, 20: e1012221. PMID: 39008525, PMCID: PMC11249266, DOI: 10.1371/journal.pcbi.1012221.
Peer-Reviewed Original Research
MeSH Keywords
The condensation of HP1α/Swi6 imparts nuclear stiffness
Williams J, Surovtsev I, Schreiner S, Chen Z, Raiymbek G, Nguyen H, Hu Y, Biteen J, Mochrie S, Ragunathan K, King M. The condensation of HP1α/Swi6 imparts nuclear stiffness. Cell Reports 2024, 43: 114373. PMID: 38900638, PMCID: PMC11348953, DOI: 10.1016/j.celrep.2024.114373.
Peer-Reviewed Original Research
The multidimensional roles of intermediate filaments - bridging genetic diversity with form, functions, and targets
Lusk C, Eriksson J. The multidimensional roles of intermediate filaments - bridging genetic diversity with form, functions, and targets. Current Opinion In Cell Biology 2024, 88: 102354. PMID: 38604107, DOI: 10.1016/j.ceb.2024.102354.
Commentaries, Editorials and Letters
Effect of loops on the mean-square displacement of Rouse-model chromatin
Yuan T, Yan H, Bailey M, Williams J, Surovtsev I, King M, Mochrie S. Effect of loops on the mean-square displacement of Rouse-model chromatin. Physical Review E 2024, 109: 044502. PMID: 38755928, DOI: 10.1103/physreve.109.044502.
Peer-Reviewed Original Research
MeSH Keywords

2023

It is time to reconsider the culture of volunteerism in undergraduate research
King M. It is time to reconsider the culture of volunteerism in undergraduate research. Journal Of Cell Science 2023, 136 PMID: 38158844, DOI: 10.1242/jcs.261865.
Peer-Reviewed Original Research
Dynamic regulation of LINC complex composition and function across tissues and contexts
King M. Dynamic regulation of LINC complex composition and function across tissues and contexts. FEBS Letters 2023, 597: 2823-2832. PMID: 37846646, DOI: 10.1002/1873-3468.14757.
Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus Statements
MeSH Keywords
An ESCRT grommet cooperates with a diffusion barrier to maintain nuclear integrity
Ader N, Chen L, Surovtsev I, Chadwick W, Rodriguez E, King M, Lusk C. An ESCRT grommet cooperates with a diffusion barrier to maintain nuclear integrity. Nature Cell Biology 2023, 25: 1465-1477. PMID: 37783794, PMCID: PMC11365527, DOI: 10.1038/s41556-023-01235-4.
Peer-Reviewed Original Research
MeSH Keywords
Changing the guard—nuclear pore complex quality control
Veldsink A, Gallardo P, Lusk C, Veenhoff L. Changing the guard—nuclear pore complex quality control. FEBS Letters 2023, 597: 2739-2749. PMID: 37715940, DOI: 10.1002/1873-3468.14739.
Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus Statements
MeSH Keywords
Acetyl-methyllysine marks chromatin at active transcription start sites
Lu-Culligan W, Connor L, Xie Y, Ekundayo B, Rose B, Machyna M, Pintado-Urbanc A, Zimmer J, Vock I, Bhanu N, King M, Garcia B, Bleichert F, Simon M. Acetyl-methyllysine marks chromatin at active transcription start sites. Nature 2023, 622: 173-179. PMID: 37731000, PMCID: PMC10845139, DOI: 10.1038/s41586-023-06565-9.
Peer-Reviewed Original Research
MeSH Keywords
Elasticity of spheres with buckled surfaces
Tian Y, McCarthy M, King M, Mochrie S. Elasticity of spheres with buckled surfaces. Physical Review E 2023, 107: 065003. PMID: 37464712, DOI: 10.1103/physreve.107.065003.
Peer-Reviewed Original Research
Loops and the activity of loop extrusion factors constrain chromatin dynamics
Bailey M, Surovtsev I, Williams J, Yan H, Yuan T, Li K, Duseau K, Mochrie S, King M. Loops and the activity of loop extrusion factors constrain chromatin dynamics. Molecular Biology Of The Cell 2023, 34: ar78. PMID: 37126401, PMCID: PMC10398873, DOI: 10.1091/mbc.e23-04-0119.
Peer-Reviewed Original Research
MeSH Keywords
The capsid lattice engages a bipartite NUP153 motif to mediate nuclear entry of HIV-1 cores
Shen Q, Kumari S, Xu C, Jang S, Shi J, Burdick R, Levintov L, Xiong Q, Wu C, Devarkar S, Tian T, Tripler T, Hu Y, Yuan S, Temple J, Feng Q, Lusk C, Aiken C, Engelman A, Perilla J, Pathak V, Lin C, Xiong Y. The capsid lattice engages a bipartite NUP153 motif to mediate nuclear entry of HIV-1 cores. Proceedings Of The National Academy Of Sciences Of The United States Of America 2023, 120: e2202815120. PMID: 36943880, PMCID: PMC10068764, DOI: 10.1073/pnas.2202815120.
Peer-Reviewed Original Research
MeSH Keywords
Modeling HIV-1 nuclear entry with nucleoporin-gated DNA-origami channels
Shen Q, Feng Q, Wu C, Xiong Q, Tian T, Yuan S, Shi J, Bedwell G, Yang R, Aiken C, Engelman A, Lusk C, Lin C, Xiong Y. Modeling HIV-1 nuclear entry with nucleoporin-gated DNA-origami channels. Nature Structural & Molecular Biology 2023, 30: 425-435. PMID: 36807645, PMCID: PMC10121901, DOI: 10.1038/s41594-023-00925-9.
Peer-Reviewed Original Research
MeSH Keywords

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