Skip to Main Content

Some loci currently being studied for genetic variation

Projects
Alcohol metabolism and alcoholism

Examples of particular genes/gene regions under study

Selected publications  exploring theme

ADH@  alcohol dehydrogenase gene cluster on chr 4 Han et al., (2007)
ALDH2 aldehyde dehydrogenase 2 on chr 12 Oota et al., (2004)
TAS2R38 taste receptor, type 2, member 38 on chr 7 Duffy et al., (2004)
Human population origins and evolution

Examples of particular datasets and analyses

Selected publications  exploring theme

The pattern of human diversification Tishkoff & Kidd., (2004)
ADH Molecular Evolution Oota et al., (2007)
SNPs and haplotypes on populations Kidd et al., (2004)
STRPs on CEPH Diversity Panel Rosenberg et al., (2002)
ADH1B*47His geographic distribution Li et al., (2007)

Li et al., (2008)

Ancestry informative SNPs in East Asia Kim et al., (2005)
Signals of natural selection

Examples of particular datasets and analyses

Selected publications  exploring theme

Selection for ADH1B Han et al., (2007)
Linkage Disequilibrium

Examples of particular genes/gene regions under study

Selected publications  exploring theme

Haplotype frequencies at DRD2, HOXB, PAH Kidd et al., (2000)

Kidd et al., (2004)

Quantifying LD along a segment of DNA Sawyer et al., (2005)
LD and transferability of tagging SNPs Gu et al., (2007)
Neuropsychiatric disorders—candidate genes

Examples of particular genes/gene regions under study

Selected publications  exploring theme

17q25 near TBCD (Tourette syndrome) Paschou et al. (2004)

Speed et al. (2008)

COMT chr 22 (schizophrenia) Palmatier et al. (2004)

Mukherjee et al. (2008)

ADH chr 4 (alcoholism) Han et al., (2007)

Li et al., (2007)

Forensics

Examples of studies

Selected publications  exploring theme

Panels of SNPs for individual identification

Kidd et al. (2006)

Pakstis et al. (2007)

Software utilities:

HAPLOT

Gu et al. (2005)

Databases:

ALFRED

Rajeevan et al. (2005)

Methodology

Paschou et al. (2007)