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Irma Dominguez Vigil, MSc, PhD

Postdoctoral Associate

Contact Information

Irma Dominguez Vigil, MSc, PhD

Lab Location

Mailing Address

  • Therapeutic Radiology

    15 York Street, Hunter Building (HRT)

    New Haven, Connecticut 06510

    United States

Biography

Irma Dominguez-Vigil earned her undergraduate degree in Pharmaceutical Biology and Chemistry at the School of Chemistry, from the Universidad Autonoma de Nuevo Leon (UANL) in Mexico (2013). She then obtained her Master’s degree in Pharmacy under the supervision of Dr. Benito Mata-Cardenas and Dr. Maria Camacho-Corona at the School of Chemistry, UANL (2015). Later, she earned a PhD degree in Molecular Biology and Genetic Engineering at the School of Medicine, UANL (2020), under the mentorship of Dr. Hugo A. Barrera-Saldana, where she explored genetic biomarkers using noninvasive techniques, such as liquid biopsies, as diagnostic tools for the early detection of gynecological cancers. During her doctoral studies, she obtained an International Academic Exchange Award (CONACyT) to Collaborate at Nuvance Health in Danbury, CT (2018-2020), where she worked with Patient Derived Cell Lines isolated from endometrial, ovarian, and sarcoma tumors as preclinical models for drug sensitivity. Presently, Dr. Dominguez-Vigil has been working on the effects of the small molecule CFI-400945 as an enhancer of radiation therapy in Non-small cell lung cancer (NSCLC) and exploring the interaction of STING with the response to DNA damaging therapy in Head and neck squamous cell carcinoma (HNSCC.

Education & Training

  • PhD
    Universidad Autonoma de Nuevo Leon, Molecular Biology and Genetic Engineering (2020)
  • MSc
    Universidad Autonoma de Nuevo Leon, Pharmacy (2015)
  • BSc
    Universidad Autonoma de Nuevo Leon, Pharmaceutical Biology and Chemistry (2013)

Activities

  • PLK4 Inhibition as a Strategy to Enhance the Non-Small Cell Lung Cancer Radiation Response
    New Haven, CT, United States 2022
    Radiobiology and Genome Integrity-Research Program
  • Endometrial adenocarcinoma: relationship between tumor volume and its clinical-pathological characteristics
    Monterrey, N.L., Mexico 2018
    XLV Congress of the National Academy of Medicine
  • Epidemiology of Endometrial Cancer in a cohort of patients from the North East and Central Mexico
    Cancún, Q.R., Mexico 2017
    XXII Latin American Conference of Gynecology & Obstetrics
  • Isolation and Characterization of Tr-DNA from the urine of patients with Gynecological Diseases
    Edinburg, TX, United States 2017
    Inaugural Research Symposium- The University of Texas Rio Grande Valley
  • Monoterpenes as anti-Giardia agents: Activity of Citral, Geraniol and (-) Carvone
    Monterrey, N.L., Mexico 2015
    XXVIII National Congress of Research in Medicine
  • Antiprotozoan activity of Poliomintha Gray
    Monterrey, N.L., Mexico 2015
    III International Congress of Chemistry and Green Engineering
  • In vitro anti-giadia activity of the hexane extract of Foeniculum vulgare and its main components
    Monterrey, N.L., Mexico 2015
    III International Congress of Chemistry and Green Engineering
  • Anti-Giardia activity of the hexane extract of Citrus aurantifolia (Cristm) Swingle and some of its components
    Monterrey, N.L., Mexico 2014
    National Symposium of Pharmaceutical Sciences and Biomedicine
  • Quantification of lead in popular candies of the metropolitan area of Monterrey, Nuevo Leon
    Monterrey, N.L., Mexico 2011
    International Congress of Pharmaceutical Biology and Chemists

Honors & Recognition

AwardAwarding OrganizationDate
Academic Exchange Travel AwardCONACyT2018
Doctoral dissertation fellowshipCONACyT2015
Master dissertation fellowshipCONACyT2013

Professional Service

OrganizationRoleDate
Pharmaceutical BiologyReviewer2024 - Present
Yale Postgraduate Association- 3rd Annual SymposiumScientific Judge, 3rd Annual Symposium, Yale Postgraduate Association2023 - Present
Yale Postdoctoral Association-Yale Buddy ProgramMentor2023 - Present
Biopreservation and BiobankingReviewer2020 - Present
Journal of Cancer Metastasis and TreatmentReviewer2020 - Present
Cancer MedicineReviewer2020 - Present

Departments & Organizations