2020
An in vivo atlas of host–pathogen transcriptomes during Streptococcus pneumoniae colonization and disease
D’Mello A, Riegler AN, Martínez E, Beno SM, Ricketts TD, Foxman EF, Orihuela CJ, Tettelin H. An in vivo atlas of host–pathogen transcriptomes during Streptococcus pneumoniae colonization and disease. Proceedings Of The National Academy Of Sciences Of The United States Of America 2020, 117: 33507-33518. PMID: 33318198, PMCID: PMC7777036, DOI: 10.1073/pnas.2010428117.Peer-Reviewed Original ResearchConceptsStreptococcus pneumoniae colonizationHost gene expression profilesHost defense pathwaysOrgan damagePneumoniae colonizationProinflammatory responseInvasive diseaseAnatomical sitesTherapeutic targetInterferon responseDisease statesDiseaseGene expression profilesLungOrgan-specific mannerVivoPneumoniaPathogenesisKidneyBloodResponse
1999
Integrating Conflicting Chemotactic Signals
Foxman E, Kunkel E, Butcher E. Integrating Conflicting Chemotactic Signals. Journal Of Cell Biology 1999, 147: 577-588. PMID: 10545501, PMCID: PMC2151176, DOI: 10.1083/jcb.147.3.577.Peer-Reviewed Original Research
1997
Chemoattractant receptor cross talk as a regulatory mechanism in leukocyte adhesion and migration
Campbell J, Foxman E, Butcher E. Chemoattractant receptor cross talk as a regulatory mechanism in leukocyte adhesion and migration. European Journal Of Immunology 1997, 27: 2571-2578. PMID: 9368612, DOI: 10.1002/eji.1830271016.Peer-Reviewed Original ResearchMeSH KeywordsAntigens, CDCell AdhesionChemotaxis, LeukocyteDrug InteractionsHumansInterleukin-8N-Formylmethionine Leucyl-PhenylalanineNeutrophilsReceptors, Formyl PeptideReceptors, ImmunologicReceptors, InterleukinReceptors, Interleukin-8AReceptors, PeptideSignal TransductionTransfectionVascular Cell Adhesion Molecule-1ConceptsIL-8Leukocyte adhesionIL-8 receptor AChemoattractant receptorsComplex cytokine milieuInterleukin-8 receptorFormyl peptide receptorMultiple chemoattractant receptorsChemotactic responseFMLP-stimulated adhesionReceptor cross talkCytokine milieuChemokine receptorsLymphoid cellsLeukocyte migrationReceptor AFormyl peptidePeptide receptorHuman neutrophilsMultiple receptorsReceptorsMigratory responseChemoattractant responsesInvasive bacteriaAsymmetric inhibition