2022
Compression stockings for treating vasovagal syncope (COMFORTS-II) trial: Rationale and design of a triple-blind, multi-center, randomized controlled trial
Tavolinejad H, Poopak A, Sadeghian S, Bozorgi A, Oraii A, Mollazadeh R, Emkanjoo Z, Kiarsi M, Shahabi J, Jalali A, Alaeddini F, Ariannejad H, Yadangi S, Oraii S, Kheirkhah J, Assadianrad M, Aminorroaya A, Tajdini M. Compression stockings for treating vasovagal syncope (COMFORTS-II) trial: Rationale and design of a triple-blind, multi-center, randomized controlled trial. American Heart Journal 2022, 249: 57-65. PMID: 35405100, DOI: 10.1016/j.ahj.2022.04.002.Peer-Reviewed Original ResearchConceptsElastic compression stockingsRandomized controlled trialsVasovagal syncopeProportion of participantsCompression stockingsTriple-blindLifestyle modification recommendationsVenous returnCo-primary outcomesPatient-reported adverse effectsTreat vasovagal syncopeVasovagal syncope recurrencesDiary sheetsSecondary outcomesStudy armsReduced venous returnSyncope recurrenceTrial backgroundSyncopal episodesFollow-upClinical trialsParticipantsMulti-centerOnline randomizationRecurrence
2020
Comparison of trinitroglycerin and adenosine as provocative agents for head-up tilt test in patients with unexplained syncope: a semi-crossover randomized clinical trial with prospective follow-up
Tajdini M, Aminorroaya A, Rahimi B, Mortazavi S, Vasheghani Farahani A, Sadeghian S, Easapour Moghadam M, Soltani D, Bozorgi A. Comparison of trinitroglycerin and adenosine as provocative agents for head-up tilt test in patients with unexplained syncope: a semi-crossover randomized clinical trial with prospective follow-up. Journal Of Interventional Cardiac Electrophysiology 2020, 60: 31-39. PMID: 31907833, DOI: 10.1007/s10840-019-00652-6.Peer-Reviewed Original ResearchConceptsTransient loss of consciousnessFollow-upUnexplained syncopeProvocative agentsTilt testDiagnostic evaluationPositive response to HUTTHead-up tilt testResponse to HUTTSuspected vasovagal syncopeRandomized clinical trialsDiagnosis of unexplained syncopeStatistically significant differenceDiagnostic yieldLoss of consciousnessRandomized patientsEvaluating patientsVasovagal syncopeVasovagal responseClinical trialsIntravenous ADPatientsSyncopeTrinitroglycerinRe-admission