Publications

Transforming Hypertension Diagnosis and Management in The Era of Artificial Intelligence: A 2023 National Heart, Lung, and Blood Institute (NHLBI) Workshop Report.Shimbo D, Shah RU, Abdalla M, Agarwal R, Ahmad FS, Anaya G, Attia ZI, Bull S, Chang AR, Commodore-Mensah Y, Ferdinand K, Kawamoto K, Khera R, Leopold J, Luo J, Makhni S, Mortazavi BJ, Oh YS, Savage LC, Spatz ES, Stergiou G, Turakhia MP, Whelton PK, Yancy CW, Iturriaga E. Hypertension. 2025 Jan; 2024 Jul 16. PMID: 39011653.
An Ensemble Deep Learning Algorithm for Structural Heart Disease Screening Using Electrocardiographic Images: PRESENT SHD.Dhingra LS, Aminorroaya A, Sangha V, Pedroso AF, Shankar SV, Coppi A, Foppa M, Brant LC, Barreto SM, Ribeiro ALP, Krumholz HM, Oikonomou EK, Khera R. medRxiv. 2024 Dec 27; 2024 Dec 27. PMID: 39417095.
Tracking the pre-clinical progression of transthyretin amyloid cardiomyopathy using artificial intelligence-enabled electrocardiography and echocardiography.Oikonomou EK, Sangha V, Vasisht Shankar S, Coppi A, Krumholz HM, Nasir K, Miller EJ, Gallegos-Kattan C, Al-Mallah MH, Al-Kindi S, Khera R. medRxiv. 2024 Dec 24; 2024 Dec 24. PMID: 39252891.
Artificial Intelligence Enabled Prediction of Heart Failure Risk from Single-lead Electrocardiograms.Dhingra LS, Aminorroaya A, Pedroso AF, Khunte A, Sangha V, McIntyre D, Chow CK, Asselbergs FW, Brant LC, Barreto SM, Ribeiro ALP, Krumholz HM, Oikonomou EK, Khera R. medRxiv. 2024 Dec 21; 2024 Dec 21. PMID: 38854022.
Artificial Intelligence Applications for Electrocardiography to Define New Digital Biomarkers of Cardiovascular Risk.Sangha V, Khera R. Circ Cardiovasc Qual Outcomes. 2024 Dec; 2024 Nov 14. PMID: 39540286.
A Multicenter Evaluation of the Impact of Therapies on Deep Learning-Based Electrocardiographic Hypertrophic Cardiomyopathy Markers.Dhingra LS, Sangha V, Aminorroaya A, Bryde R, Gaballa A, Ali AH, Mehra N, Krumholz HM, Sen S, Kramer CM, Martinez MW, Desai MY, Oikonomou EK, Khera R. Am J Cardiol. 2024 Nov 23; 2024 Nov 23. PMID: 39581517.
Cardiac magnetic resonance markers of pre-clinical hypertrophic and dilated cardiomyopathy in genetic variant carriers.Croon PM, van Vugt M, Allaart CP, Ruijsink B, Elliott PM, Asselbergs FW, Khera R, Bezzina CR, Winter M, Schmidt AF. medRxiv. 2024 Nov 18; 2024 Nov 18. PMID: 39606349.
Expanding artificial intelligence to understudied populations: congenital heart disease as the next frontier.Oikonomou EK, Khera R. Eur Heart J. 2024 Nov 11; 2024 Nov 11. PMID: 39523016.
Impact of the COVID-19 pandemic on hospital-based heart failure care in New South Wales, Australia: a linked data cohort study.McIntyre D, Quintans D, Kazi S, Min H, He WQ, Marschner S, Khera R, Nassar N, Chow CK. BMC Health Serv Res. 2024 Nov 8; 2024 Nov 8. PMID: 39516863.
Natural Language Processing of Clinical Documentation to Assess Functional Status in Patients With Heart Failure.Adejumo P, Thangaraj PM, Dhingra LS, Aminorroaya A, Zhou X, Brandt C, Xu H, Krumholz HM, Khera R. JAMA Netw Open. 2024 Nov 4; 2024 Nov 4. PMID: 39509128.
Validating International Classification of Diseases Code 10th Revision algorithms for accurate identification of pulmonary embolism.Bikdeli B, Khairani CD, Bejjani A, Lo YC, Mahajan S, Caraballo C, Jimenez JV, Krishnathasan D, Zarghami M, Rashedi S, Jimenez D, Barco S, Secemsky EA, Klok FA, Hunsaker AR, Aghayev A, Muriel A, Hussain MA, Appah-Sampong A, Lu Y, Lin Z, Mojibian H, Aneja S, Khera R, Konstantinides S, Goldhaber SZ, Wang L, Zhou L, Monreal M, Piazza G, Krumholz HM. J Thromb Haemost. 2024 Nov 4; 2024 Nov 4. PMID: 39505153.
National Patterns of Remote Patient Monitoring Service Availability at US Hospitals and their Readmission Performance for Cardiovascular Conditions.Pedroso AF, Lin Z, Ross JS, Khera R. medRxiv. 2024 Oct 16; 2024 Oct 16. PMID: 39484237.
Automated Identification of Heart Failure With Reduced Ejection Fraction Using Deep Learning-Based Natural Language Processing.Nargesi AA, Adejumo P, Dhingra LS, Rosand B, Hengartner A, Coppi A, Benigeri S, Sen S, Ahmad T, Nadkarni GN, Lin Z, Ahmad FS, Krumholz HM, Khera R. JACC Heart Fail. 2024 Oct 9; 2024 Oct 9. PMID: 39453355.
Development and Multinational Validation of an Ensemble Deep Learning Algorithm for Detecting and Predicting Structural Heart Disease Using Noisy Single-lead Electrocardiograms.Aminorroaya A, Dhingra LS, Pedroso Camargos A, Vasisht Shankar S, Coppi A, Khunte A, Foppa M, Brant LC, Barreto SM, Ribeiro ALP, Krumholz HM, Oikonomou EK, Khera R. medRxiv. 2024 Oct 8; 2024 Oct 8. PMID: 39417103.
Automated Transformation of Unstructured Cardiovascular Diagnostic Reports into Structured Datasets Using Sequentially Deployed Large Language Models.Shankar SV, Dhingra LS, Aminorroaya A, Adejumo P, Nadkarni GN, Xu H, Brandt C, Oikonomou EK, Pedroso AF, Khera R. medRxiv. 2024 Oct 8; 2024 Oct 8. PMID: 39417094.
Racial and Ethnic Disparities in Age-Specific All-Cause Mortality During the COVID-19 Pandemic.Faust JS, Renton B, Bongiovanni T, Chen AJ, Sheares KD, Du C, Essien UR, Fuentes-Afflick E, Haywood T, Khera R, King T, Li SX, Lin Z, Lu Y, Marshall ADA, Ndumele CD, Opara I, Loarte-Rodriguez T, Sawano M, Taparra K, Taylor HA, Watson KE, Yancy CW, Krumholz HM. JAMA Netw Open. 2024 Oct 1; 2024 Oct 1. PMID: 39392630.
Reviewer Experience Detecting and Judging Human Versus Artificial Intelligence Content: The Stroke Journal Essay Contest.Silva GS, Khera R, Schwamm LH. Stroke. 2024 Oct; 2024 Sep 3. PMID: 39224979.
Cardiovascular care with digital twin technology in the era of generative artificial intelligence.Thangaraj PM, Benson SH, Oikonomou EK, Asselbergs FW, Khera R. Eur Heart J. 2024 Sep 26; 2024 Sep 26. PMID: 39322420.
Retrieval-Augmented Generation for Extracting CHA(2)DS(2)-VASc Risk Factors from Unstructured Clinical Notes in Patients with Atrial Fibrillation.Adejumo P, Thangaraj P, Shankar SV, Dhingra LS, Aminorroaya A, Khera R. medRxiv. 2024 Sep 22; 2024 Sep 22. PMID: 39371151.
Artificial intelligence-enhanced patient evaluation: bridging art and science.Oikonomou EK, Khera R. Eur Heart J. 2024 Sep 14. PMID: 38976371.
A Novel Digital Twin Strategy to Examine the Implications of Randomized Clinical Trials for Real-World Populations.Thangaraj PM, Shankar SV, Huang S, Nadkarni GN, Mortazavi BJ, Oikonomou EK, Khera R. medRxiv. 2024 Sep 6; 2024 Sep 6. PMID: 38585929.
Cause-Specific Mortality Rates Among the US Black Population.Arun AS, Caraballo C, Sawano M, Lu Y, Khera R, Yancy CW, Krumholz HM. JAMA Netw Open. 2024 Sep 3; 2024 Sep 3. PMID: 39348122.
Comparative Effectiveness of Second-Line Antihyperglycemic Agents for Cardiovascular Outcomes: A Multinational, Federated Analysis of LEGEND-T2DM.Khera R, Aminorroaya A, Dhingra LS, Thangaraj PM, Pedroso Camargos A, Bu F, Ding X, Nishimura A, Anand TV, Arshad F, Blacketer C, Chai Y, Chattopadhyay S, Cook M, Dorr DA, Duarte-Salles T, DuVall SL, Falconer T, French TE, Hanchrow EE, Kaur G, Lau WCY, Li J, Li K, Liu Y, Lu Y, Man KKC, Matheny ME, Mathioudakis N, McLeggon JA, McLemore MF, Minty E, Morales DR, Nagy P, Ostropolets A, Pistillo A, Phan TP, Pratt N, Reyes C, Richter L, Ross JS, Ruan E, Seager SL, Simon KR, Viernes B, Yang J, Yin C, You SC, Zhou JJ, Ryan PB, Schuemie MJ, Krumholz HM, Hripcsak G, Suchard MA. J Am Coll Cardiol. 2024 Sep 3. PMID: 39197980.
Artificial Intelligence-Enhanced Risk Stratification of Cancer Therapeutics-Related Cardiac Dysfunction Using Electrocardiographic Images.Oikonomou EK, Sangha V, Dhingra LS, Aminorroaya A, Coppi A, Krumholz HM, Baldassarre LA, Khera R. Circ Cardiovasc Qual Outcomes. 2024 Sep 2; 2024 Sep 2. PMID: 39221857.
Correlation between hospital rates of survival to discharge and long-term survival for in-hospital cardiac arrest: Insights from Get With The Guidelines®-Resuscitation registry.Khera R, Aminorroaya A, Kennedy KF, Chan PS. Resuscitation. 2024 Sep; 2024 Jul 18. PMID: 39029583.
Local large language models for privacy-preserving accelerated review of historic echocardiogram reports.Vaid A, Duong SQ, Lampert J, Kovatch P, Freeman R, Argulian E, Croft L, Lerakis S, Goldman M, Khera R, Nadkarni GN. J Am Med Inform Assoc. 2024 Sep 1. PMID: 38687616.
Multimodal fusion learning for long QT syndrome pathogenic genotypes in a racially diverse population.Jiang J, Thi Vy HM, Charney A, Kovatch P, Reddy V, Jayaraman P, Do R, Khera R, Chugh S, Bhatt DL, Vaid A, Lampert J, Nadkarni GN. NPJ Digit Med. 2024 Aug 24; 2024 Aug 24. PMID: 39181999.
AI-enabled diagnosis from an electrocardiogram image: the next frontier of innovation in a century-old technology.Khera R. Heart. 2024 Aug 14; 2024 Aug 14. PMID: 39048290.
Excess Cardiovascular Mortality Among Black Americans 2000-2022.Arun AS, Sawano M, Lu Y, Warner F, Caraballo C, Khera R, Echols MR, Yancy CW, Krumholz HM. J Am Coll Cardiol. 2024 Aug 6; 2024 Jun 18. PMID: 38901531.
Video-Based Kinematic Analysis of Movement Quality in a Phase 3 Clinical Trial of Troriluzole in Adults with Spinocerebellar Ataxia: A Post Hoc Analysis.L'Italien GJ, Oikonomou EK, Khera R, Potashman MH, Beiner MW, Maclaine GDH, Schmahmann JD, Perlman S, Coric V. Neurol Ther. 2024 Aug; 2024 May 30. PMID: 38814532.
Internal Tremors and Vibrations in Long COVID: A Cross-Sectional Study.Zhou T, Sawano M, Arun AS, Caraballo C, Michelsen T, McAlpine LS, Bhattacharjee B, Lu Y, Khera R, Huang C, Warner F, Herrin J, Iwasaki A, Krumholz HM. Am J Med. 2024 Jul 26; 2024 Jul 26. PMID: 39069199.
Designing medical artificial intelligence systems for global use: focus on interoperability, scalability, and accessibility.Oikonomou EK, Khera R. Hellenic J Cardiol. 2024 Jul 16; 2024 Jul 16. PMID: 39025234.
Efficient deep learning-based automated diagnosis from echocardiography with contrastive self-supervised learning.Holste G, Oikonomou EK, Mortazavi BJ, Wang Z, Khera R. Commun Med (Lond). 2024 Jul 6; 2024 Jul 6. PMID: 38971887.
Transforming Cardiovascular Care With Artificial Intelligence: From Discovery to Practice: JACC State-of-the-Art Review.Khera R, Oikonomou EK, Nadkarni GN, Morley JR, Wiens J, Butte AJ, Topol EJ. J Am Coll Cardiol. 2024 Jul 2. PMID: 38925729.
Real-World Experience and Outcomes With Percutaneous Coronary Intervention for Protected Versus Unprotected Left Main Coronary Artery Disease: Insights from the Veteran Affairs Clinical Assessment Reporting and Tracking Program.Gonzalez PE, Hebbe A, Hussain Y, Khera R, Banerjee S, Plomondon ME, Waldo SW, Pfau SE, Curtis JP, Shah SM. Am J Cardiol. 2024 Jul 1; 2024 Apr 26. PMID: 38677666.
Leveraging the Full Potential of Wearable Devices in Cardiomyopathies.Oikonomou EK, Khera R. J Card Fail. 2024 Jul; 2024 Mar 5. PMID: 38452997.
Artificial intelligence-guided detection of under-recognized cardiomyopathies on point-of-care cardiac ultrasound: a multi-center study.Oikonomou EK, Vaid A, Holste G, Coppi A, McNamara RL, Baloescu C, Krumholz HM, Wang Z, Apakama DJ, Nadkarni GN, Khera R. medRxiv. 2024 Jun 29; 2024 Jun 29. PMID: 38559021.
Artificial Intelligence for Cardiovascular Care-Part 1: Advances: JACC Review Topic of the Week.Elias P, Jain SS, Poterucha T, Randazzo M, Lopez Jimenez F, Khera R, Perez M, Ouyang D, Pirruccello J, Salerno M, Einstein AJ, Avram R, Tison GH, Nadkarni G, Natarajan V, Pierson E, Beecy A, Kumaraiah D, Haggerty C, Avari Silva JN, Maddox TM. J Am Coll Cardiol. 2024 Jun 18; 2024 Apr 7. PMID: 38593946.
Artificial Intelligence in Cardiovascular Care-Part 2: Applications: JACC Review Topic of the Week.Jain SS, Elias P, Poterucha T, Randazzo M, Lopez Jimenez F, Khera R, Perez M, Ouyang D, Pirruccello J, Salerno M, Einstein AJ, Avram R, Tison GH, Nadkarni G, Natarajan V, Pierson E, Beecy A, Kumaraiah D, Haggerty C, Avari Silva JN, Maddox TM. J Am Coll Cardiol. 2024 Jun 18; 2024 Apr 7. PMID: 38593945.
Characteristics of High-Performing Hospitals in Cardiogenic Shock Following Acute Myocardial Infarction.Saha A, Li S, de Lemos JA, Pandey A, Bhatt DL, Fonarow GC, Nallamothu BK, Wang TY, Navar AM, Peterson E, Matsouaka RA, Bavry AA, Das SR, Grodin JL, Khera R, Drazner MH, Kumbhani DJ. Am J Cardiol. 2024 Jun 15; 2024 Apr 5. PMID: 38583700.
Performance of contemporary cardiovascular risk stratification scores in Brazil: an evaluation in the ELSA-Brasil study.Pedroso Camargos A, Barreto S, Brant L, Ribeiro ALP, Dhingra LS, Aminorroaya A, Bittencourt M, Figueiredo RC, Khera R. Open Heart. 2024 Jun 11; 2024 Jun 11. PMID: 38862252.
Study Protocol for the Artificial Intelligence-Driven Evaluation of Structural Heart Diseases Using Wearable Electrocardiogram (ID-SHD).Aminorroaya A, Dhingra LS, Camargos AP, Shankar SV, Khunte A, Sangha V, Sen S, McNamara RL, Haynes N, Oikonomou EK, Khera R. medRxiv. 2024 Jun 3; 2024 Jun 3. PMID: 38562867.
Data Interoperability for Ambulatory Monitoring of Cardiovascular Disease: A Scientific Statement From the American Heart Association.Armoundas AA, Ahmad FS, Bennett DA, Chung MK, Davis LL, Dunn J, Narayan SM, Slotwiner DJ, Wiley KK Jr, Khera R. Circ Genom Precis Med. 2024 Jun; 2024 May 23. PMID: 38779844.
A Multimodal Video-Based AI Biomarker for Aortic Stenosis Development and Progression.Oikonomou EK, Holste G, Yuan N, Coppi A, McNamara RL, Haynes NA, Vora AN, Velazquez EJ, Li F, Menon V, Kapadia SR, Gill TM, Nadkarni GN, Krumholz HM, Wang Z, Ouyang D, Khera R. JAMA Cardiol. 2024 Jun 1. PMID: 38581644.
Computational Phenomapping of Randomized Clinical Trials to Enable Assessment of their Real-world Representativeness and Personalized Inference.Thangaraj PM, Oikonomou EK, Dhingra LS, Aminorroaya A, Jayaram R, Suchard MA, Khera R. medRxiv. 2024 May 16; 2024 May 16. PMID: 38798457.
The PAX LC Trial: A Decentralized, Phase 2, Randomized, Double-Blind Study of Nirmatrelvir/Ritonavir Compared with Placebo/Ritonavir for Long COVID.Krumholz HM, Sawano M, Bhattacharjee B, Caraballo C, Khera R, Li SX, Herrin J, Coppi A, Holub J, Henriquez Y, Johnson MA, Goddard TB, Rocco E, Hummel AC, Al Mouslmani M, Putrino DF, Carr KD, Carvajal-Gonzalez S, Charnas L, De Jesus M, Ziegler FW 3rd, Iwasaki A. Am J Med. 2024 May 10; 2024 May 10. PMID: 38735354.
Artificial intelligence-enhanced exposomics: novel insights into cardiovascular health.Khera R. Eur Heart J. 2024 May 7. PMID: 38544282.
Development and multinational validation of an algorithmic strategy for high Lp(a) screening.Aminorroaya A, Dhingra LS, Oikonomou EK, Saadatagah S, Thangaraj P, Vasisht Shankar S, Spatz ES, Khera R. Nat Cardiovasc Res. 2024 May; 2024 May 9. PMID: 39195936.
Real-world evaluation of an algorithmic machine-learning-guided testing approach in stable chest pain: a multinational, multicohort study.Oikonomou EK, Aminorroaya A, Dhingra LS, Partridge C, Velazquez EJ, Desai NR, Krumholz HM, Miller EJ, Khera R. Eur Heart J Digit Health. 2024 May; 2024 Apr 8. PMID: 38774380.
Validation of the European SCORE2 models in a Canadian primary care cohort.Sud M, Sivaswamy A, Austin PC, Abdel-Qadir H, Anderson TJ, Khera R, Naimark DMJ, Lee DS, Roifman I, Thanassoulis G, Tu K, Wijeysundera HC, Ko DT. Eur J Prev Cardiol. 2024 Apr 18. PMID: 37946603.
Scalable Risk Stratification for Heart Failure Using Artificial Intelligence applied to 12-lead Electrocardiographic Images: A Multinational Study.Dhingra LS, Aminorroaya A, Sangha V, Camargos AP, Asselbergs FW, Brant LC, Barreto SM, Ribeiro ALP, Krumholz HM, Oikonomou EK, Khera R. medRxiv. 2024 Apr 3; 2024 Apr 3. PMID: 38633808.
Biometric contrastive learning for data-efficient deep learning from electrocardiographic images.Sangha V, Khunte A, Holste G, Mortazavi BJ, Wang Z, Oikonomou EK, Khera R. J Am Med Inform Assoc. 2024 Apr 3. PMID: 38269618.
Reporting Use of AI in Research and Scholarly Publication-JAMA Network Guidance.Flanagin A, Pirracchio R, Khera R, Berkwits M, Hswen Y, Bibbins-Domingo K. JAMA. 2024 Apr 2. PMID: 38451540.
A Deep Learning Approach for Automated Extraction of Functional Status and New York Heart Association Class for Heart Failure Patients During Clinical Encounters.Adejumo P, Thangaraj P, Dhingra LS, Aminorroaya A, Zhou X, Brandt C, Xu H, Krumholz HM, Khera R. medRxiv. 2024 Apr 1; 2024 Apr 1. PMID: 38633789.
Artificial intelligence-enhanced risk stratification of cancer therapeutics-related cardiac dysfunction using electrocardiographic images.Oikonomou EK, Sangha V, Dhingra LS, Aminorroaya A, Coppi A, Krumholz HM, Baldassarre LA, Khera R. medRxiv. 2024 Mar 19; 2024 Mar 19. PMID: 38562897.
A Multicenter Evaluation of the Impact of Therapies on Deep Learning-based Electrocardiographic Hypertrophic Cardiomyopathy Markers.Dhingra LS, Sangha V, Aminorroaya A, Bryde R, Gaballa A, Ali AH, Mehra N, Krumholz HM, Sen S, Kramer CM, Martinez MW, Desai MY, Oikonomou EK, Khera R. medRxiv. 2024 Mar 3; 2024 Mar 3. PMID: 38293023.
Summertime for Cardiovascular AI.Khera R, Wiens J. Circ Cardiovasc Qual Outcomes. 2024 Mar; 2024 Mar 19. PMID: 38502717.
A Multimodality Video-Based AI Biomarker For Aortic Stenosis Development And Progression.Oikonomou EK, Holste G, Yuan N, Coppi A, McNamara RL, Haynes N, Vora AN, Velazquez EJ, Li F, Menon V, Kapadia SR, Gill TM, Nadkarni GN, Krumholz HM, Wang Z, Ouyang D, Khera R. medRxiv. 2024 Feb 29; 2024 Feb 29. PMID: 37808685.
Automated Diagnostic Reports from Images of Electrocardiograms at the Point-of-Care.Khunte A, Sangha V, Oikonomou EK, Dhingra LS, Aminorroaya A, Coppi A, Shankar SV, Mortazavi BJ, Bhatt DL, Krumholz HM, Nadkarni GN, Vaid A, Khera R. medRxiv. 2024 Feb 18; 2024 Feb 18. PMID: 38405776.
Comparative Effectiveness of Second-line Antihyperglycemic Agents for Cardiovascular Outcomes: A Large-scale, Multinational, Federated Analysis of the LEGEND-T2DM Study.Khera R, Aminorroaya A, Dhingra LS, Thangaraj PM, Camargos AP, Bu F, Ding X, Nishimura A, Anand TV, Arshad F, Blacketer C, Chai Y, Chattopadhyay S, Cook M, Dorr DA, Duarte-Salles T, DuVall SL, Falconer T, French TE, Hanchrow EE, Kaur G, Lau WC, Li J, Li K, Liu Y, Lu Y, Man KK, Matheny ME, Mathioudakis N, McLeggon JA, McLemore MF, Minty E, Morales DR, Nagy P, Ostropolets A, Pistillo A, Phan TP, Pratt N, Reyes C, Richter L, Ross J, Ruan E, Seager SL, Simon KR, Viernes B, Yang J, Yin C, You SC, Zhou JJ, Ryan PB, Schuemie MJ, Krumholz HM, Hripcsak G, Suchard MA. medRxiv. 2024 Feb 8; 2024 Feb 8. PMID: 38370787.
Quantitative Prediction of Right Ventricular Size and Function From the ECG.Duong SQ, Vaid A, My VTH, Butler LR, Lampert J, Pass RH, Charney AW, Narula J, Khera R, Sakhuja A, Greenspan H, Gelb BD, Do R, Nadkarni GN. J Am Heart Assoc. 2024 Jan 2; 2023 Dec 29. PMID: 38156471.
Eligibility for Cardiovascular Risk Reduction Therapy in the United States Based on SELECT Trial Criteria: Insights From the National Health and Nutrition Examination Survey.Lu Y, Liu Y, Jastreboff AM, Khera R, Ndumele CD, Rodriguez F, Watson KE, Krumholz HM. Circ Cardiovasc Qual Outcomes. 2024 Jan; 2023 Nov 11. PMID: 37950677.
Identification of Hypertrophic Cardiomyopathy on Electrocardiographic Images with Deep Learning.Sangha V, Dhingra LS, Oikonomou E, Aminorroaya A, Sikand NV, Sen S, Krumholz HM, Khera R. medRxiv. 2023 Dec 28; 2023 Dec 28. PMID: 38234746.
Automation Bias and Assistive AI: Risk of Harm From AI-Driven Clinical Decision Support.Khera R, Simon MA, Ross JS. JAMA. 2023 Dec 19. PMID: 38112824.
RCT-Twin-GAN Generates Digital Twins of Randomized Control Trials Adapted to Real-world Patients to Enhance their Inference and Application.Thangaraj PM, Shankar SV, Oikonomou EK, Khera R. medRxiv. 2023 Dec 15; 2023 Dec 15. PMID: 38106089.
Patterns of Digoxin Prescribing for Medicare Beneficiaries in the United States 2013-2019.See C, Wheelock KM, Caraballo C, Khera R, Annapureddy A, Mahajan S, Lu Y, Krumholz HM, Murugiah K. Am J Med Open. 2023 Dec; 2023 Jun 24. PMID: 38213879.
An explainable machine learning-based phenomapping strategy for adaptive predictive enrichment in randomized clinical trials.Oikonomou EK, Thangaraj PM, Bhatt DL, Ross JS, Young LH, Krumholz HM, Suchard MA, Khera R. NPJ Digit Med. 2023 Nov 25; 2023 Nov 25. PMID: 38001154.
Accelerating chest pain evaluation with machine learning.Thangaraj PM, Khera R. Eur Heart J Acute Cardiovasc Care. 2023 Nov 16. PMID: 37793075.
Severe aortic stenosis detection by deep learning applied to echocardiography.Holste G, Oikonomou EK, Mortazavi BJ, Coppi A, Faridi KF, Miller EJ, Forrest JK, McNamara RL, Ohno-Machado L, Yuan N, Gupta A, Ouyang D, Krumholz HM, Wang Z, Khera R. Eur Heart J. 2023 Nov 14. PMID: 37611002.
An explainable machine learning-based phenomapping strategy for adaptive predictive enrichment in randomized controlled trials.Oikonomou EK, Thangaraj PM, Bhatt DL, Ross JS, Young LH, Krumholz HM, Suchard MA, Khera R. medRxiv. 2023 Nov 1; 2023 Nov 1. PMID: 37961715.
Lifting the Veil on Advanced Heart Failure.Sandhu AT, Khera R. JACC Heart Fail. 2023 Nov; 2023 Sep 20. PMID: 37737760.
Outcomes of Percutaneous Coronary Intervention for Protected versus Unprotected Left Main Coronary Artery Disease: Insights from the VA CART Program.Gonzalez PE, Hebbe A, Hussain Y, Khera R, Banerjee S, Plomondon ME, Waldo SW, Pfau SE, Curtis JP, Shah SM. medRxiv. 2023 Oct 28; 2023 Oct 28. PMID: 37961093.
Multinational patterns of second line antihyperglycaemic drug initiation across cardiovascular risk groups: federated pharmacoepidemiological evaluation in LEGEND-T2DM.Khera R, Dhingra LS, Aminorroaya A, Li K, Zhou JJ, Arshad F, Blacketer C, Bowring MG, Bu F, Cook M, Dorr DA, Duarte-Salles T, DuVall SL, Falconer T, French TE, Hanchrow EE, Horban S, Lau WC, Li J, Liu Y, Lu Y, Man KK, Matheny ME, Mathioudakis N, McLemore MF, Minty E, Morales DR, Nagy P, Nishimura A, Ostropolets A, Pistillo A, Posada JD, Pratt N, Reyes C, Ross JS, Seager S, Shah N, Simon K, Wan EY, Yang J, Yin C, You SC, Schuemie MJ, Ryan PB, Hripcsak G, Krumholz H, Suchard MA. BMJ Med. 2023; 2023 Oct 6. PMID: 37829182.
CarDS-Plus ECG Platform: Development and Feasibility Evaluation of a Multiplatform Artificial Intelligence Toolkit for Portable and Wearable Device Electrocardiograms.Shankar SV, Oikonomou EK, Khera R. medRxiv. 2023 Oct 3; 2023 Oct 3. PMID: 37873174.
Machine learning in precision diabetes care and cardiovascular risk prediction.Oikonomou EK, Khera R. Cardiovasc Diabetol. 2023 Sep 25; 2023 Sep 25. PMID: 37749579.
Development and Multinational Validation of a Novel Algorithmic Strategy for High Lp(a) Screening.Aminorroaya A, Dhingra LS, Oikonomou EK, Saadatagah S, Thangaraj P, Shankar SV, Spatz ES, Khera R. medRxiv. 2023 Sep 19; 2023 Sep 19. PMID: 37790355.
Cardiovascular Care Innovation through Data-Driven Discoveries in the Electronic Health Record.Dhingra LS, Shen M, Mangla A, Khera R. Am J Cardiol. 2023 Sep 15; 2023 Jul 25. PMID: 37499593.
Biometric Contrastive Learning for Data-Efficient Deep Learning from Electrocardiographic Images.Sangha V, Khunte A, Holste G, Mortazavi BJ, Wang Z, Oikonomou EK, Khera R. medRxiv. 2023 Sep 14; 2023 Sep 14. PMID: 37745527.
Automated Identification of Heart Failure with Reduced Ejection Fraction using Deep Learning-based Natural Language Processing.Nargesi AA, Adejumo P, Dhingra L, Rosand B, Hengartner A, Coppi A, Benigeri S, Sen S, Ahmad T, Nadkarni GN, Lin Z, Ahmad FS, Krumholz HM, Khera R. medRxiv. 2023 Sep 11; 2023 Sep 11. PMID: 37745445.
AI in Medicine-JAMA's Focus on Clinical Outcomes, Patient-Centered Care, Quality, and Equity.Khera R, Butte AJ, Berkwits M, Hswen Y, Flanagin A, Park H, Curfman G, Bibbins-Domingo K. JAMA. 2023 Sep 5. PMID: 37566406.
Use of Smart Devices to Track Cardiovascular Health Goals in the United States.Aminorroaya A, Dhingra LS, Nargesi AA, Oikonomou EK, Krumholz HM, Khera R. JACC Adv. 2023 Sep; 2023 Aug 8. PMID: 38094515.
Detection of Left Ventricular Systolic Dysfunction From Electrocardiographic Images.Sangha V, Nargesi AA, Dhingra LS, Khunte A, Mortazavi BJ, Ribeiro AH, Banina E, Adeola O, Garg N, Brandt CA, Miller EJ, Ribeiro ALP, Velazquez EJ, Giatti L, Barreto SM, Foppa M, Yuan N, Ouyang D, Krumholz HM, Khera R. Circulation. 2023 Aug 29; 2023 Jul 25. PMID: 37489538.
Internal tremors and vibrations in long COVID: a cross-sectional study.Zhou T, Sawano M, Arun AS, Caraballo C, Michelsen T, McAlpine L, Bhattacharjee B, Lu Y, Khera R, Huang C, Warner F, Iwasaki A, Krumholz HM. medRxiv. 2023 Aug 28; 2023 Aug 28. PMID: 37693623.
Physician responses to apple watch-detected irregular rhythm alerts.Demkowicz PC, Dhruva SS, Spatz ES, Beatty AL, Ross JS, Khera R. Am Heart J. 2023 Aug; 2023 Apr 20. PMID: 37084933.
Hospital Adherence to the Federal Price Transparency Mandate: Results from a Nationally Representative Sample.Loccoh EC, Khera R, van Meijgaard J, Marsh T, Warraich HJ. J Gen Intern Med. 2023 Aug; 2023 Jan 17. PMID: 36650327.
Detection of left ventricular systolic dysfunction from single-lead electrocardiography adapted for portable and wearable devices.Khunte A, Sangha V, Oikonomou EK, Dhingra LS, Aminorroaya A, Mortazavi BJ, Coppi A, Brandt CA, Krumholz HM, Khera R. NPJ Digit Med. 2023 Jul 11; 2023 Jul 11. PMID: 37433874.
Clinical Risk Prediction Models with Meta-Learning Prototypes of Patient Heterogeneity.Zhang L, Khera R, Mortazavi BJ. Annu Int Conf IEEE Eng Med Biol Soc. 2023 Jul. PMID: 38083199.
Variation in hospital use of cardiac resynchronization therapy-defibrillator among eligible patients and association with clinical outcomes.Chui PW, Lan Z, Freeman JV, Enriquez AD, Khera R, Akar JG, Masoudi FA, Ong EL, Curtis JP. Heart Rhythm. 2023 Jul; 2023 Mar 22. PMID: 36963741.
Lifetime healthcare expenses across demographic and cardiovascular risk groups: The application of a novel modeling strategy in a large multiethnic cohort study.Khera R, Kondamudi N, Liu M, Ayers C, Spatz ES, Rao S, Essien UR, Powell-Wiley TM, Nasir K, Das SR, Capers Q, Pandey A. Am J Prev Cardiol. 2023 Jun; 2023 Mar 23. PMID: 37397263.
Use of Wearable Devices in Individuals With or at Risk for Cardiovascular Disease in the US, 2019 to 2020.Dhingra LS, Aminorroaya A, Oikonomou EK, Nargesi AA, Wilson FP, Krumholz HM, Khera R. JAMA Netw Open. 2023 Jun 1; 2023 Jun 1. PMID: 37285157.
Persistence on Novel Cardioprotective Antihyperglycemic Therapies in the United States.Nargesi AA, Clark C, Aminorroaya A, Chen L, Liu M, Reddy A, Amodeo S, Oikonomou EK, Suchard MA, McGuire DK, Lin Z, Inzucchi S, Khera R. Am J Cardiol. 2023 Jun 1; 2023 Apr 1. PMID: 37012183.
Developing Validated Tools to Identify Pulmonary Embolism in Electronic Databases: Rationale and Design of the PE-EHR+ Study.Bikdeli B, Lo YC, Khairani CD, Bejjani A, Jimenez D, Barco S, Mahajan S, Caraballo C, Secemsky EA, Klok FA, Hunsaker AR, Aghayev A, Muriel A, Wang Y, Hussain MA, Appah-Sampong A, Lu Y, Lin Z, Aneja S, Khera R, Goldhaber SZ, Zhou L, Monreal M, Krumholz HM, Piazza G. Thromb Haemost. 2023 Jun; 2023 Feb 21. PMID: 36809777.
Sex Difference in Outcomes of Acute Myocardial Infarction in Young Patients.Sawano M, Lu Y, Caraballo C, Mahajan S, Dreyer R, Lichtman JH, D'Onofrio G, Spatz E, Khera R, Onuma O, Murugiah K, Spertus JA, Krumholz HM. J Am Coll Cardiol. 2023 May 9. PMID: 37137590.
Quantitative prediction of right ventricular and size and function from the electrocardiogram.Duong SQ, Vaid A, Vy HMT, Butler LR, Lampert J, Pass RH, Charney AW, Narula J, Khera R, Greenspan H, Gelb BD, Do R, Nadkarni G. medRxiv. 2023 Apr 26; 2023 Apr 26. PMID: 37162979.
Nonexercise machine learning models for maximal oxygen uptake prediction in national population surveys.Liu Y, Herrin J, Huang C, Khera R, Dhingra LS, Dong W, Mortazavi BJ, Krumholz HM, Lu Y. J Am Med Inform Assoc. 2023 Apr 19. PMID: 36905605.
Quantifying Blood Pressure Visit-to-Visit Variability in the Real-World Setting: A Retrospective Cohort Study.Lu Y, Linderman GC, Mahajan S, Liu Y, Huang C, Khera R, Mortazavi BJ, Spatz ES, Krumholz HM. Circ Cardiovasc Qual Outcomes. 2023 Apr; 2023 Mar 8. PMID: 36883456.
Timing of Blood Draws Among Patients Hospitalized in a Large Academic Medical Center.Caraballo C, Mahajan S, Murugiah K, Mortazavi BJ, Lu Y, Khera R, Krumholz HM. JAMA. 2023 Jan 17. PMID: 36648476.
Time in therapeutic range for targeted temperature management and outcomes following out-of-hospital cardiac arrest.Wheelock KM, Chan PS, Chen L, de Lemos JA, Miller PE, Nallamothu BK, Girotra S, Khera R. Resuscitation. 2023 Jan; 2022 Nov 25. PMID: 36442596.
Unfavorable social determinants of health are associated with higher burden of financial toxicity among patients with atherosclerotic cardiovascular disease in the US: findings from the National Health Interview Survey.Valero-Elizondo J, Javed Z, Khera R, Tano ME, Dudum R, Acquah I, Hyder AA, Andrieni J, Sharma G, Blaha MJ, Virani SS, Blankstein R, Cainzos-Achirica M, Nasir K. Arch Public Health. 2022 Dec 6; 2022 Dec 6. PMID: 36474300.
Variation in coronary angiography use in Out-of-Hospital cardiac arrest.Agusala V, Dale P, Khera R, Brown SP, Idris AH, Link MS, Mody P. Resuscitation. 2022 Dec; 2022 Nov 1. PMID: 36332772.