2022
Histopathology of Colectomy Specimens Predicts Endoscopic Pouch Phenotype in Patients with Ulcerative Colitis
Akiyama S, Ollech J, Traboulsi C, Rai V, Glick L, Yi Y, Runde J, Olivas A, Weber C, Cohen R, Olortegui K, Hurst R, Umanskiy K, Shogan B, Rubin M, Dalal S, Sakuraba A, Pekow J, Chang E, Hart J, Hyman N, Rubin D. Histopathology of Colectomy Specimens Predicts Endoscopic Pouch Phenotype in Patients with Ulcerative Colitis. Digestive Diseases And Sciences 2022, 67: 4020-4031. PMID: 35288827, PMCID: PMC10966959, DOI: 10.1007/s10620-022-07405-y.Peer-Reviewed Original ResearchConceptsIleal pouch-anal anastomosisUlcerative colitisColectomy specimensTerminal ileal involvementCrohn's diseaseIleal involvementPouch fistulaFocal inflammationDeep inflammationLimb involvementPouch-anal anastomosisLogistic regression analysisIleostomy takedownPouch bodyPouch lossEndoscopic appearancePathology reviewMultivariable analysisHistologic featuresPoor prognosisPathological dataEndoscopic phenotypesHigh riskPatientsInflammation
2020
Management of Patients With Crohn’s Disease and Ulcerative Colitis During the Coronavirus Disease-2019 Pandemic: Results of an International Meeting
Rubin D, Abreu M, Rai V, Siegel C, Disease I, Ahuja V, Allez M, Ananthakrishnan A, Bernstein C, Braun J, Chowers Y, Colombel J, Danese S, D'Haens G, D'Hoore A, Dignass A, Dotan I, Dubinsky M, Ekbom A, Fleshner P, Gassull M, Gearry R, Ghosh S, Griffiths A, Halfvarson J, Hanauer S, Harpaz N, Hart A, Kamm M, Kaplan G, Koutroubakis I, Lakatos P, Levine A, Lewis J, Lindsay J, Loftus E, Louis E, Lukas M, Magro F, Mahadevan U, Mantzaris G, McGovern D, Moum B, Munkholm P, Neurath M, Ng S, O'Morain C, Panaccione R, Panes J, Peyrin-Biroulet L, Prantera C, Ran Z, Reinisch W, Remzi F, Sachar D, Sandborn W, Sartor R, Schölmerich J, Schreiber S, Siegmund B, Silverberg M, Söderholm J, Stange E, Steinwurz F, Turner D, Vatn M, Vermeire S, Brenner E, Christensen B, D'Amico F, Griffiths C, Higgins P, Kappelman M, Lees C, Regueiro M, Rosh J, Ungaro R. Management of Patients With Crohn’s Disease and Ulcerative Colitis During the Coronavirus Disease-2019 Pandemic: Results of an International Meeting. Gastroenterology 2020, 159: 6-13.e6. PMID: 32272113, PMCID: PMC7194599, DOI: 10.1053/j.gastro.2020.04.002.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsEffectiveness of Ustekinumab Dose Escalation in Patients With Crohn’s Disease
Ollech J, Normatov I, Peleg N, Wang J, Patel S, Rai V, Yi Y, Singer J, Dalal S, Sakuraba A, Cohen R, Rubin D, Pekow J. Effectiveness of Ustekinumab Dose Escalation in Patients With Crohn’s Disease. Clinical Gastroenterology And Hepatology 2020, 19: 104-110. PMID: 32109634, PMCID: PMC8665415, DOI: 10.1016/j.cgh.2020.02.035.Peer-Reviewed Original ResearchConceptsC-reactive proteinCrohn's diseaseFecal calprotectinInterval shorteningDisease activityStandard doseDose intervalMedian levelsLevels of CRPHarvey-Bradshaw Index scoreUstekinumab dose escalationSubset of patientsEndoscopic remissionClinical remissionEndoscopic evidenceDose escalationSingle centerRetrospective studyPatientsCalprotectinIndex scoreAbstractTextNormal levelsDiseaseWeeks