Publications

• Physiologic mechanisms underlying polycystic kidney disease.Boletta A, Caplan MJ. Physiol Rev. 2025 Jul 1; 2025 Feb 12. PMID: 39938884.
• Identification of polycystin 2 missense mutants targeted for endoplasmic reticulum-associated degradation.Guerriero CJ, Carattino MD, Sharp KG, Kantz LJ, Gresko NP, Caplan MJ, Brodsky JL. Am J Physiol Cell Physiol. 2025 Feb 1; 2024 Dec 23. PMID: 39714991.
• Calcium signalling and transport in the kidney.Staruschenko A, Alexander RT, Caplan MJ, Ilatovskaya DV. Nat Rev Nephrol. 2024 Aug; 2024 Apr 19. PMID: 38641658.
• Editorial: Molecular mechanisms underlying polycystic kidney disease: from the smallest bricks to the big scenario.Di Mise A, Caplan MJ, Valenti G. Front Mol Biosci. 2024; 2024 May 21. PMID: 38836108.
• Does maternal vitamin D status influence placental weight or vascular and inflammatory pathology? Secondary analysis from the Kellogg Pregnancy Study.Mead MJ, McWhorter CA, Rodgers MD, Ebeling MD, Shary JR, Gregoski MJ, Hollis BW, Hewison M, Johnson D, Caplan MJ, Wagner CL. J Steroid Biochem Mol Biol. 2023 Oct; 2023 Jul 4. PMID: 37414103.
• Author Correction: Membrane potential drives the exit from pluripotency and cell fate commitment via calcium and mTOR.Sempou E, Kostiuk V, Zhu J, Cecilia Guerra M, Tyan L, Hwang W, Camacho-Aguilar E, Caplan MJ, Zenisek D, Warmflash A, Owens NDL, Khokha MK. Nat Commun. 2023 Jun 5; 2023 Jun 5. PMID: 37277326.
• The C-terminal tail of polycystin-1 suppresses cystic disease in a mitochondrial enzyme-dependent fashion.Onuchic L, Padovano V, Schena G, Rajendran V, Dong K, Shi X, Pandya R, Rai V, Gresko NP, Ahmed O, Lam TT, Wang W, Shen H, Somlo S, Caplan MJ. Nat Commun. 2023 Mar 30; 2023 Mar 30. PMID: 36997516.
• Membrane potential drives the exit from pluripotency and cell fate commitment via calcium and mTOR.Sempou E, Kostiuk V, Zhu J, Cecilia Guerra M, Tyan L, Hwang W, Camacho-Aguilar E, Caplan MJ, Zenisek D, Warmflash A, Owens NDL, Khokha MK. Nat Commun. 2022 Nov 5; 2022 Nov 5. PMID: 36335122.
• Polycystin-2 in the Endoplasmic Reticulum: Bending Ideas about the Role of the Cilium.Caplan MJ. J Am Soc Nephrol. 2022 Aug. PMID: 35906088.
• AMPK and Polycystic Kidney Disease Drug Development: An Interesting Off-Target Target.Caplan MJ. Front Med (Lausanne). 2022; 2022 Jan 31. PMID: 35174190.
• β3 adrenergic receptor as potential therapeutic target in ADPKD.Schena G, Carmosino M, Chiurlia S, Onuchic L, Mastropasqua M, Maiorano E, Schena FP, Caplan MJ. Physiol Rep. 2021 Oct. PMID: 34676684.
• Physiology and Physiology, 2021.J Caplan M. Physiology (Bethesda). 2021 Sep 1. PMID: 34346698.
• A cut above (and below): Protein cleavage in the regulation of polycystin trafficking and signaling.Padovano V, Mistry K, Merrick D, Gresko N, Caplan MJ. Cell Signal. 2020 Aug; 2020 Apr 10. PMID: 32283256.
• Chloride channels regulate differentiation and barrier functions of the mammalian airway.He M, Wu B, Ye W, Le DD, Sinclair AW, Padovano V, Chen Y, Li KX, Sit R, Tan M, Caplan MJ, Neff N, Jan YN, Darmanis S, Jan LY. Elife. 2020 Apr 14; 2020 Apr 14. PMID: 32286221.
• Mechanisms involved in AMPK-mediated deposition of tight junction components to the plasma membrane.Wu J, Rowart P, Jouret F, Gassaway BM, Rajendran V, Rinehart J, Caplan MJ. Am J Physiol Cell Physiol. 2020 Mar 1; 2020 Jan 8. PMID: 31913699.
• Holding open the door reveals a new view of polycystin channel function.Caplan MJ. EMBO Rep. 2019 Nov 5; 2019 Sep 26. PMID: 31556469.
• Everything You Always Wanted to Know about β(3)-AR * (* But Were Afraid to Ask).Schena G, Caplan MJ. Cells. 2019 Apr 16; 2019 Apr 16. PMID: 30995798.
• Polycystin-1 regulates bone development through an interaction with the transcriptional coactivator TAZ.Merrick D, Mistry K, Wu J, Gresko N, Baggs JE, Hogenesch JB, Sun Z, Caplan MJ. Hum Mol Genet. 2019 Jan 1. PMID: 30215740.
• The Polycystin Complex Reveals Its Complexity.Padovano V, Caplan MJ. Biochemistry. 2018 Dec 26; 2018 Dec 12. PMID: 30540438.
• Newly synthesized polycystin-1 takes different trafficking pathways to the apical and ciliary membranes.Gilder AL, Chapin HC, Padovano V, Hueschen CL, Rajendran V, Caplan MJ. Traffic. 2018 Dec; 2018 Sep 24. PMID: 30125442.
• Metabolism and mitochondria in polycystic kidney disease research and therapy.Padovano V, Podrini C, Boletta A, Caplan MJ. Nat Rev Nephrol. 2018 Nov. PMID: 30120380.
• Implications of AMPK in the Formation of Epithelial Tight Junctions.Rowart P, Wu J, Caplan MJ, Jouret F. Int J Mol Sci. 2018 Jul 13; 2018 Jul 13. PMID: 30011834.
• The secretory pathway at 50: a golden anniversary for some momentous grains of silver.Matlin KS, Caplan MJ. Mol Biol Cell. 2017 Jan 15. PMID: 28082520.
• The polycystins are modulated by cellular oxygen-sensing pathways and regulate mitochondrial function.Padovano V, Kuo IY, Stavola LK, Aerni HR, Flaherty BJ, Chapin HC, Ma M, Somlo S, Boletta A, Ehrlich BE, Rinehart J, Caplan MJ. Mol Biol Cell. 2017 Jan 15; 2016 Nov 23. PMID: 27881662.
• Newly synthesized and recycling pools of the apical protein gp135 do not occupy the same compartments.Stoops EH, Hull M, Caplan MJ. Traffic. 2016 Dec; 2016 Nov 1. PMID: 27649479.
• Artificial bacterial biomimetic nanoparticles synergize pathogen-associated molecular patterns for vaccine efficacy.Siefert AL, Caplan MJ, Fahmy TM. Biomaterials. 2016 Aug; 2016 Apr 1. PMID: 27162077.
• Investigation of peanut oral immunotherapy with CpG/peanut nanoparticles in a murine model of peanut allergy.Srivastava KD, Siefert A, Fahmy TM, Caplan MJ, Li XM, Sampson HA. J Allergy Clin Immunol. 2016 Aug; 2016 Apr 26. PMID: 27130858.
• A Practical Forensic Approach to Fatal Pediatric Endocrinopathies.Caplan MJ. Acad Forensic Pathol. 2016 Jun; 2016 Jun 1. PMID: 31239897.
• The tail of polycystin-1 pays the kidney a complement.Caplan MJ. Am J Physiol Renal Physiol. 2016 Jun 1; 2016 Mar 23. PMID: 27009337.
• 2016 Robert W. Berliner Award for Excellence in Renal Physiology.Caplan MJ. Am J Physiol Renal Physiol. 2016 Apr 15; 2016 Mar 9. PMID: 26962101.
• Dual pulse-chase microscopy reveals early divergence in the biosynthetic trafficking of the Na,K-ATPase and E-cadherin.Farr GA, Hull M, Stoops EH, Bateson R, Caplan MJ. Mol Biol Cell. 2015 Dec 1; 2015 Sep 30. PMID: 26424804.
• Akt Substrate of 160 kD Regulates Na+,K+-ATPase Trafficking in Response to Energy Depletion and Renal Ischemia.Alves DS, Thulin G, Loffing J, Kashgarian M, Caplan MJ. J Am Soc Nephrol. 2015 Nov; 2015 Mar 18. PMID: 25788531.
• The periciliary ring in polarized epithelial cells is a hot spot for delivery of the apical protein gp135.Stoops EH, Hull M, Olesen C, Mistry K, Harder JL, Rivera-Molina F, Toomre D, Caplan MJ. J Cell Biol. 2015 Oct 26. PMID: 26504168.
• Chemical and Physical Sensors in the Regulation of Renal Function.Pluznick JL, Caplan MJ. Clin J Am Soc Nephrol. 2015 Sep 4; 2014 Oct 3. PMID: 25280495.
• Polycystin-1 Is a Cardiomyocyte Mechanosensor That Governs L-Type Ca2+ Channel Protein Stability.Pedrozo Z, Criollo A, Battiprolu PK, Morales CR, Contreras-Ferrat A, Fernández C, Jiang N, Luo X, Caplan MJ, Somlo S, Rothermel BA, Gillette TG, Lavandero S, Hill JA. Circulation. 2015 Jun 16; 2015 Apr 17. PMID: 25888683.
• Knockdown of ezrin causes intrahepatic cholestasis by the dysregulation of bile fluidity in the bile duct epithelium in mice.Hatano R, Akiyama K, Tamura A, Hosogi S, Marunaka Y, Caplan MJ, Ueno Y, Tsukita S, Asano S. Hepatology. 2015 May; 2015 Mar 23. PMID: 25311759.
• Developmental lung malformations in children: recent advances in imaging techniques, classification system, and imaging findings.Thacker PG, Schooler GR, Caplan MJ, Lee EY. J Thorac Imaging. 2015 Jan. PMID: 25525781.
• Trafficking to the apical and basolateral membranes in polarized epithelial cells.Stoops EH, Caplan MJ. J Am Soc Nephrol. 2014 Jul; 2014 Mar 20. PMID: 24652803.
• A growing lesion on the cheek.Rawl JW, Caplan MJ, Lentsch EJ. JAMA Otolaryngol Head Neck Surg. 2014 Apr. PMID: 24557595.
• Polycystin-1 cleavage and the regulation of transcriptional pathways.Merrick D, Bertuccio CA, Chapin HC, Lal M, Chauvet V, Caplan MJ. Pediatr Nephrol. 2014 Apr; 2013 Jul 4. PMID: 23824180.
• SNAP-tag to monitor trafficking of membrane proteins in polarized epithelial cells.Stoops EH, Farr GA, Hull M, Caplan MJ. Methods Mol Biol. 2014. PMID: 24947381.
• Activation of the Ca²+-sensing receptor induces deposition of tight junction components to the epithelial cell plasma membrane.Jouret F, Wu J, Hull M, Rajendran V, Mayr B, Schöfl C, Geibel J, Caplan MJ. J Cell Sci. 2013 Nov 15; 2013 Sep 6. PMID: 24013548.
• Antigen-specific, antibody-coated, exosome-like nanovesicles deliver suppressor T-cell microRNA-150 to effector T cells to inhibit contact sensitivity.Bryniarski K, Ptak W, Jayakumar A, Püllmann K, Caplan MJ, Chairoungdua A, Lu J, Adams BD, Sikora E, Nazimek K, Marquez S, Kleinstein SH, Sangwung P, Iwakiri Y, Delgato E, Redegeld F, Blokhuis BR, Wojcikowski J, Daniel AW, Groot Kormelink T, Askenase PW. J Allergy Clin Immunol. 2013 Jul; 2013 May 31. PMID: 23727037.
• An inversin convergence. Focus on "Inversin modulates the cortical actin network during mitosis".Caplan MJ. Am J Physiol Cell Physiol. 2013 Jul 1; 2013 May 15. PMID: 23677797.
• A rapidly expanding orbital lesion.Magrath GN, Cheeseman EW, Eiseman AS, Caplan MJ. J Pediatr. 2013 Jul; 2013 Feb 28. PMID: 23453771.
• Epithelial morphogenesis of MDCK cells in three-dimensional collagen culture is modulated by interleukin-8.Wells EK, Yarborough O 3rd, Lifton RP, Cantley LG, Caplan MJ. Am J Physiol Cell Physiol. 2013 May 15; 2013 Mar 13. PMID: 23485708.
• Olfactory receptor responding to gut microbiota-derived signals plays a role in renin secretion and blood pressure regulation.Pluznick JL, Protzko RJ, Gevorgyan H, Peterlin Z, Sipos A, Han J, Brunet I, Wan LX, Rey F, Wang T, Firestein SJ, Yanagisawa M, Gordon JI, Eichmann A, Peti-Peterdi J, Caplan MJ. Proc Natl Acad Sci U S A. 2013 Mar 12; 2013 Feb 11. PMID: 23401498.
• Polycystin-1C terminus cleavage and its relation with polycystin-2, two proteins involved in polycystic kidney disease.Bertuccio CA, Caplan MJ. Medicina (B Aires). 2013. PMID: 23570767.
• VIP17/MAL expression modulates epithelial cyst formation and ciliogenesis.Takiar V, Mistry K, Carmosino M, Schaeren-Wiemers N, Caplan MJ. Am J Physiol Cell Physiol. 2012 Oct 15; 2012 Aug 15. PMID: 22895261.
• Novel sensory signaling systems in the kidney.Pluznick JL, Caplan MJ. Curr Opin Nephrol Hypertens. 2012 Jul. PMID: 22569342.
• Disseminated neuroendocrine carcinoma in a pediatric patient: a rare case and diagnostic challenge.Post GR, Lewis JA, Hudspeth MP, Caplan MJ, Lazarchick J. J Pediatr Hematol Oncol. 2012 Apr. PMID: 22134610.
• The γ-secretase cleavage product of polycystin-1 regulates TCF and CHOP-mediated transcriptional activation through a p300-dependent mechanism.Merrick D, Chapin H, Baggs JE, Yu Z, Somlo S, Sun Z, Hogenesch JB, Caplan MJ. Dev Cell. 2012 Jan 17; 2011 Dec 15. PMID: 22178500.
• Preactivation of AMPK by metformin may ameliorate the epithelial cell damage caused by renal ischemia.Seo-Mayer PW, Thulin G, Zhang L, Alves DS, Ardito T, Kashgarian M, Caplan MJ. Am J Physiol Renal Physiol. 2011 Dec; 2011 Aug 17. PMID: 21849490.
• Macrophages promote cyst growth in polycystic kidney disease.Karihaloo A, Koraishy F, Huen SC, Lee Y, Merrick D, Caplan MJ, Somlo S, Cantley LG. J Am Soc Nephrol. 2011 Oct; 2011 Sep 15. PMID: 21921140.
• Polycystic kidney disease: pathogenesis and potential therapies.Takiar V, Caplan MJ. Biochim Biophys Acta. 2011 Oct; 2010 Dec 10. PMID: 21146605.
• Polycystin-2 and phosphodiesterase 4C are components of a ciliary A-kinase anchoring protein complex that is disrupted in cystic kidney diseases.Choi YH, Suzuki A, Hajarnis S, Ma Z, Chapin HC, Caplan MJ, Pontoglio M, Somlo S, Igarashi P. Proc Natl Acad Sci U S A. 2011 Jun 28; 2011 Jun 13. PMID: 21670265.
• AMP-activated protein kinase (AMPK) activation and glycogen synthase kinase-3β (GSK-3β) inhibition induce Ca2+-independent deposition of tight junction components at the plasma membrane.Zhang L, Jouret F, Rinehart J, Sfakianos J, Mellman I, Lifton RP, Young LH, Caplan MJ. J Biol Chem. 2011 May 13; 2011 Mar 7. PMID: 21383016.
• Activating AMP-activated protein kinase (AMPK) slows renal cystogenesis.Takiar V, Nishio S, Seo-Mayer P, King JD Jr, Li H, Zhang L, Karihaloo A, Hallows KR, Somlo S, Caplan MJ. Proc Natl Acad Sci U S A. 2011 Feb 8; 2011 Jan 24. PMID: 21262823.
• Protein phosphatase 2A interacts with the Na,K-ATPase and modulates its trafficking by inhibition of its association with arrestin.Kimura T, Han W, Pagel P, Nairn AC, Caplan MJ. PLoS One. 2011; 2011 Dec 29. PMID: 22242112.
• Renal cystic disease proteins play critical roles in the organization of the olfactory epithelium.Pluznick JL, Rodriguez-Gil DJ, Hull M, Mistry K, Gattone V, Johnson CA, Weatherbee S, Greer CA, Caplan MJ. PLoS One. 2011; 2011 May 13. PMID: 21614130.
• Polycystin-1 surface localization is stimulated by polycystin-2 and cleavage at the G protein-coupled receptor proteolytic site.Chapin HC, Rajendran V, Caplan MJ. Mol Biol Cell. 2010 Dec; 2010 Oct 27. PMID: 20980620.
• AS160 associates with the Na+,K+-ATPase and mediates the adenosine monophosphate-stimulated protein kinase-dependent regulation of sodium pump surface expression.Alves DS, Farr GA, Seo-Mayer P, Caplan MJ. Mol Biol Cell. 2010 Dec; 2010 Oct 13. PMID: 20943949.
• The cell biology of polycystic kidney disease.Chapin HC, Caplan MJ. J Cell Biol. 2010 Nov 15. PMID: 21079243.
• MAL/VIP17, a new player in the regulation of NKCC2 in the kidney.Carmosino M, Rizzo F, Procino G, Basco D, Valenti G, Forbush B, Schaeren-Wiemers N, Caplan MJ, Svelto M. Mol Biol Cell. 2010 Nov 15; 2010 Sep 22. PMID: 20861303.
• Association with {beta}-COP regulates the trafficking of the newly synthesized Na,K-ATPase.Morton MJ, Farr GA, Hull M, Capendeguy O, Horisberger JD, Caplan MJ. J Biol Chem. 2010 Oct 29; 2010 Aug 26. PMID: 20801885.
• Exosome release of β-catenin: a novel mechanism that antagonizes Wnt signaling.Chairoungdua A, Smith DL, Pochard P, Hull M, Caplan MJ. J Cell Biol. 2010 Sep 20; 2010 Sep 13. PMID: 20837771.
• TLR9-targeted biodegradable nanoparticles as immunization vectors protect against West Nile encephalitis.Demento SL, Bonafé N, Cui W, Kaech SM, Caplan MJ, Fikrig E, Ledizet M, Fahmy TM. J Immunol. 2010 Sep 1; 2010 Jul 26. PMID: 20660705.
• Lymphocytes accelerate epithelial tight junction assembly: role of AMP-activated protein kinase (AMPK).Tang XX, Chen H, Yu S, Zhang L, Caplan MJ, Chan HC. PLoS One. 2010 Aug 23; 2010 Aug 23. PMID: 20808811.
• Telling kidneys to cease and decyst.Takiar V, Caplan MJ. Nat Med. 2010 Jul. PMID: 20613749.
• Ligand-modified gene carriers increased uptake in target cells but reduced DNA release and transfection efficiency.Cu Y, LeMoëllic C, Caplan MJ, Saltzman WM. Nanomedicine. 2010 Apr; 2009 Oct 2. PMID: 19800989.
• Partial correction of cystic fibrosis defects with PLGA nanoparticles encapsulating curcumin.Cartiera MS, Ferreira EC, Caputo C, Egan ME, Caplan MJ, Saltzman WM. Mol Pharm. 2010 Feb 1. PMID: 19886674.
• Polycystin-1 C-terminal cleavage is modulated by polycystin-2 expression.Bertuccio CA, Chapin HC, Cai Y, Mistry K, Chauvet V, Somlo S, Caplan MJ. J Biol Chem. 2009 Jul 31; 2009 Jun 2. PMID: 19491093.
• Membrane proteins follow multiple pathways to the basolateral cell surface in polarized epithelial cells.Farr GA, Hull M, Mellman I, Caplan MJ. J Cell Biol. 2009 Jul 27; 2009 Jul 20. PMID: 19620635.
• Inflammasome-activating nanoparticles as modular systems for optimizing vaccine efficacy.Demento SL, Eisenbarth SC, Foellmer HG, Platt C, Caplan MJ, Mark Saltzman W, Mellman I, Ledizet M, Fikrig E, Flavell RA, Fahmy TM. Vaccine. 2009 May 18; 2009 Apr 3. PMID: 19428913.
• The uptake and intracellular fate of PLGA nanoparticles in epithelial cells.Cartiera MS, Johnson KM, Rajendran V, Caplan MJ, Saltzman WM. Biomaterials. 2009 May; 2009 Feb 20. PMID: 19232712.
• Functional expression of the olfactory signaling system in the kidney.Pluznick JL, Zou DJ, Zhang X, Yan Q, Rodriguez-Gil DJ, Eisner C, Wells E, Greer CA, Wang T, Firestein S, Schnermann J, Caplan MJ. Proc Natl Acad Sci U S A. 2009 Feb 10; 2009 Jan 27. PMID: 19174512.
• Detecting the surface localization and cytoplasmic cleavage of membrane-bound proteins.Chapin HC, Rajendran V, Capasso A, Caplan MJ. Methods Cell Biol. 2009; 2009 Dec 23. PMID: 20362093.
• Dystroglycan and AMP kinase: polarity's protectors when the power goes out.Zhang L, Seo-Mayer P, Caplan MJ. Dev Cell. 2009 Jan. PMID: 19154710.
• The cytoplasmic tail dileucine motif LL572 determines the glycosylation pattern of membrane-type 1 matrix metalloproteinase.Ludwig T, Theissen SM, Morton MJ, Caplan MJ. J Biol Chem. 2008 Dec 19; 2008 Oct 27. PMID: 18955496.
• Polycystin-1 C-terminal tail associates with beta-catenin and inhibits canonical Wnt signaling.Lal M, Song X, Pluznick JL, Di Giovanni V, Merrick DM, Rosenblum ND, Chauvet V, Gottardi CJ, Pei Y, Caplan MJ. Hum Mol Genet. 2008 Oct 15; 2008 Jul 16. PMID: 18632682.
• A case of orbital Rosai-Dorfman disease responding to radiotherapy.Cooper SL, Chavis PS, Fortney JA, Watkins JM, Caplan MJ, Jenrette JM 3rd. J Pediatr Hematol Oncol. 2008 Oct. PMID: 19011471.
• Epithelial junctions and polarity: complexes and kinases.Caplan MJ, Seo-Mayer P, Zhang L. Curr Opin Nephrol Hypertens. 2008 Sep. PMID: 18695392.
• Design opportunities for actively targeted nanoparticle vaccines.Fahmy TM, Demento SL, Caplan MJ, Mellman I, Saltzman WM. Nanomedicine (Lond). 2008 Jun. PMID: 18510429.
• Protein trafficking in polarized cells.Duffield A, Caplan MJ, Muth TR. Int Rev Cell Mol Biol. 2008. PMID: 19081536.
• Arrestins and spinophilin competitively regulate Na+,K+-ATPase trafficking through association with a large cytoplasmic loop of the Na+,K+-ATPase.Kimura T, Allen PB, Nairn AC, Caplan MJ. Mol Biol Cell. 2007 Nov; 2007 Sep 5. PMID: 17804821.
• MAL decreases the internalization of the aquaporin-2 water channel.Kamsteeg EJ, Duffield AS, Konings IB, Spencer J, Pagel P, Deen PM, Caplan MJ. Proc Natl Acad Sci U S A. 2007 Oct 16; 2007 Oct 10. PMID: 17940053.
• Transport protein sorting in polarized epithelial cells.Zhang L, Caplan MJ. Sheng Li Xue Bao. 2007 Aug 25. PMID: 17700970.
• The future of the pump.Caplan MJ. J Clin Gastroenterol. 2007 Jul. PMID: 17575526.
• Tetraspan proteins: regulators of renal structure and function.Caplan MJ, Kamsteeg EJ, Duffield A. Curr Opin Nephrol Hypertens. 2007 Jul. PMID: 17565278.
• Pathology quiz case 1. Infantile myofibromatosis.Turner J, Skinner M, Caplan MJ, Gillespie MB. Arch Otolaryngol Head Neck Surg. 2007 Jun. PMID: 17576917.
• Acute deaths in nonpregnant adults due to invasive streptococcal infections.Batalis NI, Caplan MJ, Schandl CA. Am J Forensic Med Pathol. 2007 Mar. PMID: 17325468.
• AMP-activated protein kinase regulates the assembly of epithelial tight junctions.Zhang L, Li J, Young LH, Caplan MJ. Proc Natl Acad Sci U S A. 2006 Nov 14; 2006 Nov 6. PMID: 17088526.
• CFTR is required for PKA-regulated ATP sensitivity of Kir1.1 potassium channels in mouse kidney.Lu M, Leng Q, Egan ME, Caplan MJ, Boulpaep EL, Giebisch GH, Hebert SC. J Clin Invest. 2006 Mar; 2006 Feb 9. PMID: 16470247.
• Polycystin-2 regulates proliferation and branching morphogenesis in kidney epithelial cells.Grimm DH, Karihaloo A, Cai Y, Somlo S, Cantley LG, Caplan MJ. J Biol Chem. 2006 Jan 6; 2005 Nov 8. PMID: 16278216.
• An extracellular loop of the human non-gastric H,K-ATPase alpha-subunit is involved in apical plasma membrane polarization.Lerner M, Lemke D, Bertram H, Schillers H, Oberleithner H, Caplan MJ, Reinhardt J. Cell Physiol Biochem. 2006; 2006 Aug 15. PMID: 16914892.
• The C-terminal tail of the polycystin-1 protein interacts with the Na,K-ATPase alpha-subunit.Zatti A, Chauvet V, Rajendran V, Kimura T, Pagel P, Caplan MJ. Mol Biol Cell. 2005 Nov; 2005 Aug 17. PMID: 16107561.
• Mechanical stimuli induce cleavage and nuclear translocation of the polycystin-1 C terminus.Chauvet V, Tian X, Husson H, Grimm DH, Wang T, Hiesberger T, Igarashi P, Bennett AM, Ibraghimov-Beskrovnaya O, Somlo S, Caplan MJ. J Clin Invest. 2004 Nov. PMID: 15545994.
• Gastric parietal cell acid secretion in mice can be regulated independently of H/K ATPase endocytosis.Nguyen NV, Gleeson PA, Courtois-Coutry N, Caplan MJ, Van Driel IR. Gastroenterology. 2004 Jul. PMID: 15236181.
• Sorting of H,K-ATPase beta-subunit in MDCK and LLC-PK cells is independent of mu 1B adaptin expression.Duffield A, Fölsch H, Mellman I, Caplan MJ. Traffic. 2004 Jun. PMID: 15117319.
• Curcumin, a major constituent of turmeric, corrects cystic fibrosis defects.Egan ME, Pearson M, Weiner SA, Rajendran V, Rubin D, Glöckner-Pagel J, Canny S, Du K, Lukacs GL, Caplan MJ. Science. 2004 Apr 23. PMID: 15105504.