Publications

2023

Single-cell analysis reveals inflammatory interactions driving macular degeneration.Kuchroo M, DiStasio M, Song E, Calapkulu E, Zhang L, Ige M, Sheth AH, Majdoubi A, Menon M, Tong A, Godavarthi A, Xing Y, Gigante S, Steach H, Huang J, Huguet G, Narain J, You K, Mourgkos G, Dhodapkar RM, Hirn MJ, Rieck B, Wolf G, Krishnaswamy S, Hafler BP. Nat Commun. 2023 May 5; 2023 May 5. PMID: 37147305.
Innate immune biology in age-related macular degeneration.Ascunce K, Dhodapkar RM, Huang D, Hafler BP. Front Cell Dev Biol. 2023; 2023 Feb 28. PMID: 36926522.
Inflammation of the retinal pigment epithelium drives early-onset photoreceptor degeneration in Mertk-associated retinitis pigmentosa.Mercau ME, Akalu YT, Mazzoni F, Gyimesi G, Alberto EJ, Kong Y, Hafler BP, Finnemann SC, Rothlin CV, Ghosh S. Sci Adv. 2023 Jan 20; 2023 Jan 20. PMID: 36662852.

Glial-mediated neuroinflammatory mechanisms in age-related macular degeneration.Dhodapkar RM, Martell D, Hafler BP. Semin Immunopathol. 2022 Sep; 2022 May 5. PMID: 35513496.
Utilization of Crowdfunding for Cataract and LASIK Procedures.Patil SA, Luu A, Vail DG, Watane A, Levine R, Hafler B, Parikh R. Semin Ophthalmol. 2022 Jul 4; 2022 Mar 30. PMID: 35353643.

Altered photoreceptor metabolism in mouse causes late stage age-related macular degeneration-like pathologies.Cheng SY, Cipi J, Ma S, Hafler BP, Kanadia RN, Brush RS, Agbaga MP, Punzo C. Proc Natl Acad Sci U S A. 2020 Jun 9; 2020 May 20. PMID: 32434914.

Single-cell transcriptomic atlas of the human retina identifies cell types associated with age-related macular degeneration.Menon M, Mohammadi S, Davila-Velderrain J, Goods BA, Cadwell TD, Xing Y, Stemmer-Rachamimov A, Shalek AK, Love JC, Kellis M, Hafler BP. Nat Commun. 2019 Oct 25; 2019 Oct 25. PMID: 31653841.
Author Correction: Single-cell transcriptomic analysis of Alzheimer's disease.Mathys H, Davila-Velderrain J, Peng Z, Gao F, Mohammadi S, Young JZ, Menon M, He L, Abdurrob F, Jiang X, Martorell AJ, Ransohoff RM, Hafler BP, Bennett DA, Kellis M, Tsai LH. Nature. 2019 Jul. PMID: 31209304.
Single-cell transcriptomic analysis of Alzheimer's disease.Mathys H, Davila-Velderrain J, Peng Z, Gao F, Mohammadi S, Young JZ, Menon M, He L, Abdurrob F, Jiang X, Martorell AJ, Ransohoff RM, Hafler BP, Bennett DA, Kellis M, Tsai LH. Nature. 2019 Jun; 2019 May 1. PMID: 31042697.

Course of Ocular Function in PRPF31 Retinitis Pigmentosa.Hafler BP, Comander J, Weigel DiFranco C, Place EM, Pierce EA. Semin Ophthalmol. 2016. PMID: 26959129.

Progressive retinal degeneration and accumulation of autofluorescent lipopigments in Progranulin deficient mice.Hafler BP, Klein ZA, Jimmy Zhou Z, Strittmatter SM. Brain Res. 2014 Nov 7; 2014 Sep 16. PMID: 25234724.
Angiophagy prevents early embolus washout but recanalizes microvessels through embolus extravasation.Grutzendler J, Murikinati S, Hiner B, Ji L, Lam CK, Yoo T, Gupta S, Hafler BP, Adelman RA, Yuan P, Rodriguez G. Sci Transl Med. 2014 Mar 5. PMID: 24598589.

Transcription factor Olig2 defines subpopulations of retinal progenitor cells biased toward specific cell fates.Hafler BP, Surzenko N, Beier KT, Punzo C, Trimarchi JM, Kong JH, Cepko CL. Proc Natl Acad Sci U S A. 2012 May 15; 2012 Apr 27. PMID: 22543161.

Jerky/Earthbound facilitates cell-specific Wnt/Wingless signalling by modulating β-catenin-TCF activity.Benchabane H, Xin N, Tian A, Hafler BP, Nguyen K, Ahmed A, Ahmed Y. EMBO J. 2011 Apr 20; 2011 Mar 11. PMID: 21399610.

Expression and function of Nkx6.3 in vertebrate hindbrain.Hafler BP, Choi MY, Shivdasani RA, Rowitch DH. Brain Res. 2008 Jul 30; 2008 May 6. PMID: 18586225.

Evidence for motoneuron lineage-specific regulation of Olig2 in the vertebrate neural tube.Sun T, Hafler BP, Kaing S, Kitada M, Ligon KL, Widlund HR, Yuk DI, Stiles CD, Rowitch DH. Dev Biol. 2006 Apr 1; 2006 Feb 8. PMID: 16469306.