2017
Lipid transport by TMEM24 at ER–plasma membrane contacts regulates pulsatile insulin secretion
Lees JA, Messa M, Sun EW, Wheeler H, Torta F, Wenk MR, De Camilli P, Reinisch KM. Lipid transport by TMEM24 at ER–plasma membrane contacts regulates pulsatile insulin secretion. Science 2017, 355 PMID: 28209843, PMCID: PMC5414417, DOI: 10.1126/science.aah6171.Peer-Reviewed Original ResearchConceptsER–plasma membrane contactsLipid transportLipid-binding modulesMembrane contactPhosphoinositide signalingMembrane proteinsPrecursor phosphatidylinositolProtein 24Reversible localizationEndoplasmic reticulumTMEM24Β-cellsPhosphatidylinositolInsulin secretionCalcium oscillationsCytosolic calciumDephosphorylationType II diabetesPhosphorylationSignalingProteinReticulumSecretionII diabetesTransport
1979
Dopamine inhibits adenylate cyclase in human prolactin-secreting pituitary adenomas
DE CAMILLI P, MACCONI D, SPADA A. Dopamine inhibits adenylate cyclase in human prolactin-secreting pituitary adenomas. Nature 1979, 278: 252-254. PMID: 423973, DOI: 10.1038/278252a0.Peer-Reviewed Original ResearchConceptsDA receptorsPRL secretionProlactin-secreting pituitary adenomasAdenylate cyclaseBasal adenylate cyclaseSame pharmacological propertiesClasses of receptorsDopamine inhibitsDopaminergic agonistsProlactin secretionPituitary adenomasNormal anteriorPRL adenomasPharmacological propertiesReceptorsSecretionCyclic AMPAdenomasCyclaseAgonistsAnteriorPRL
1978
1538 DOPAMINE SENSITIVE ADENYLATE-CYCLASE IN GH AND PRL HUMAN PITUITARY ADENOMAS: ITS POSSIBLE ROLE ON HORMONE SECRETION
De Camilli P, Spada A, Giovannelli M, Meldolesi J, Faglia G. 1538 DOPAMINE SENSITIVE ADENYLATE-CYCLASE IN GH AND PRL HUMAN PITUITARY ADENOMAS: ITS POSSIBLE ROLE ON HORMONE SECRETION. 1978, 596. DOI: 10.1016/b978-0-08-023768-8.51549-8.Peer-Reviewed Original Research