2010
Fgfr2 Is Required for the Development of the Medial Prefrontal Cortex and Its Connections with Limbic Circuits
Stevens HE, Smith KM, Maragnoli ME, Fagel D, Borok E, Shanabrough M, Horvath TL, Vaccarino FM. Fgfr2 Is Required for the Development of the Medial Prefrontal Cortex and Its Connections with Limbic Circuits. Journal Of Neuroscience 2010, 30: 5590-5602. PMID: 20410112, PMCID: PMC2868832, DOI: 10.1523/jneurosci.5837-09.2010.Peer-Reviewed Original ResearchConceptsMedial prefrontal cortexCerebral cortexFibroblast growth factor receptorCKO miceExcitatory neuronsPrefrontal cortexCortical neuron developmentEntire cerebral cortexRadial glial cellsSpecific fibroblast growth factor receptorsGrowth factor receptorGABAergic neuronsLimbic circuitsCortical neuronsGlial cellsSubcortical stationsBed nucleusCortical developmentLimbic systemStria terminalisSynaptic terminalsSecondary decreaseNeuronal precursorsVentricular zoneNeuron development
2006
Annotation: Tourette syndrome: a relentless drumbeat – driven by misguided brain oscillations
Leckman JF, Vaccarino FM, Kalanithi PS, Rothenberger A. Annotation: Tourette syndrome: a relentless drumbeat – driven by misguided brain oscillations. Journal Of Child Psychology And Psychiatry 2006, 47: 537-550. PMID: 16712630, DOI: 10.1111/j.1469-7610.2006.01620.x.Peer-Reviewed Original ResearchConceptsTourette syndromeNormal central nervous system functionCentral nervous system functionNeural oscillationsAberrant neural oscillationsSuccessful behavioral treatmentNervous system functionMotor actionsSurgical interventionThalamocortical rhythmsElectrophysiological effectsElectrophysiological findingsSensorimotor gatingSensory urgeSynaptic plasticityTic suppressionAmeliorative effectBehavioral treatmentMotor responsePrefrontal cortexAberrant oscillationsCoherent network activityEffective modulatorPrefrontal regionsRecent evidence