1995
Basic Fibroblast Growth Factor Increases the Number of Excitatory Neurons Containing Glutamate in the Cerebral Cortex
Vaccarino F, Schwartz M, Hartigan D, Leckman J. Basic Fibroblast Growth Factor Increases the Number of Excitatory Neurons Containing Glutamate in the Cerebral Cortex. Cerebral Cortex 1995, 5: 64-78. PMID: 7719131, DOI: 10.1093/cercor/5.1.64.Peer-Reviewed Original ResearchConceptsBasic fibroblast growth factorNerve growth factorGlutamate-containing neuronsCerebral cortexFibroblast growth factorGrowth factorAspartate-containing neuronsDifferent neurotransmitter phenotypesNumber of GABARatio of glutamateStem cellsNeurotransmitter phenotypeExcitatory neuronsInhibitory neuronsRat telencephalonVentricular zoneBFGF mRNAGABANeuronsCortexGlutamateDiffusible factorsThreefold increaseCellsFactors
1987
Ganglioside inhibition of glutamate-mediated protein kinase C translocation in primary cultures of cerebellar neurons.
Vaccarino F, Guidotti A, Costa E. Ganglioside inhibition of glutamate-mediated protein kinase C translocation in primary cultures of cerebellar neurons. Proceedings Of The National Academy Of Sciences Of The United States Of America 1987, 84: 8707-8711. PMID: 2825205, PMCID: PMC299615, DOI: 10.1073/pnas.84.23.8707.Peer-Reviewed Original ResearchConceptsGranule cellsProtein kinase C translocationExcitatory amino acid neurotransmitter receptorsAmino acid neurotransmitter receptorsPrimary culturesGlutamate-mediated Ca2Cerebellar granule cellsHigh affinity recognition sitesPKC translocationNeurotransmitter receptorsRemoval of Ca2Cerebellar neuronsActivation of PKCC translocationNeuronal membranesGanglioside inhibitionRedistribution of PKCIncubation mediumGlutamateCa2PKCActivation